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121.
A systematic review of health service interventions to improve linkage with or retention in HIV care
The importance of early linkage to and continuing retention in HIV care is increasingly recognised, particularly in light of the implications poor linkage and retention rates have for the effectiveness of HIV treatment as prevention strategies. The purpose of this systematic review was to examine the effectiveness of healthcare interventions in improving patient linkage to or retention in HIV care. We systematically searched PubMed (MEDLINE and PubMed-only citations) and EMBASE databases for articles reporting the original results of randomised controlled trials, and used a standard data collection form to extract information on study characteristics and outcome data. Five articles met the inclusion criteria, of which two articles focused on linkage to care and three on retention in care. The methodological quality, both of internal and external validity, of most of the trials was suboptimal. Wide variation in the interventions and outcome measures meant synthesis of the results using meta-analysis was not appropriate. This review shows evidence that interventions based on supporting patient self-management improves linkage to, and possibly retention in, care. Interventions aimed at delivery service design may also be effective, although evidence in this review was limited. It is vital that interventions are developed to improve patient engagement in HIV care. The dearth of research identified by this review highlights the need for well-designed trials of interventions in this area in the future. 相似文献
122.
123.
Ramusino Matteo Cotta Garibotto Valentina Bacchin Ruggero Altomare Daniele Dodich Alessandra Assal Frederic Mendes Aline Costa Alfredo Tinazzi Michele Morbelli Silvia D. Bauckneht Matteo Picco Agnese Dottorini Massimo E. Tranfaglia Cristina Farotti Lucia Salvadori Nicola Moretti Davide Savelli Giordano Tarallo Anna Nobili Flavio Parapini Maura Cavaliere Carlo Salvatore Elena Salvatore Marco Boccardi Marina Frisoni Giovanni B 《European journal of nuclear medicine and molecular imaging》2020,47(2):270-280
European Journal of Nuclear Medicine and Molecular Imaging - To compare the incremental diagnostic value of amyloid-PET and CSF (Aβ42, tau, and phospho-tau) in AD diagnosis in patients with... 相似文献
124.
Colaço Camila Schoueri Alves Stefany Sousa Nolli Luciana Marangni Pinheiro Willie Oliveira de Oliveira Danilo Gustavo Rodrigues Santos Beatriz Werneck Lopes Pic-Taylor Aline Mortari Márcia Renata Caldas Eloisa Dutra 《Metabolic brain disease》2020,35(5):739-751
Metabolic Brain Disease - Ayahuasca is a hallucinogenic beverage that affects the serotonergic system and have therapeutic potential for many diseases and disorders, including depression and drug... 相似文献
125.
Michele de Freitas Neves Silva Gabriela Novelli Oliveira Aline Maino Pergola-Marconato Rafael Silva Marconato Eliete Boaventura Bargas Izilda Esmenia Muglia Araujo 《Revista latino-americana de enfermagem》2014,22(2):218-225
Objective
to develop, validate the contents and verify the reliability of a risk classification protocol for an Emergency Unit.Method
the content validation was developed in a University Hospital in a country town located in the state of Sao Paulo and was carried out in two stages: the first with the individual assessment of specialists and the second with the meeting between the researchers and the specialists. The use of the protocol followed a specific guide. Concerning reliability, the concordance or equivalent method among observers was used.Results
the protocol developed showed to have content validity and, after the suggested changes were made, there were excellent results concerning reliability.Conclusion
the assistance flow chart was shown to be easy to use, and facilitate the search for the complaint in each assistance priority. 相似文献126.
AIDS in adults 50 years of age and over: characteristics,trends and
spatial distribution of the risk
Jordana de Almeida Nogueira Ant?nia Oliveira Silva Laísa Ribeiro de Sá Sandra Aparecida de Almeida Aline Aparecida Monroe Tereza Cristina Scatena Villa 《Revista latino-americana de enfermagem》2014,22(3):355-363
Objective
to analyze the sociodemographic characteristics, epidemic trend and spatial distribution of the risk of AIDS in adults 50 years of age and over.Method
population-based, ecological study, that used secondary data from the Notifiable Disease Information System (Sinan/AIDS) of Paraíba state from the period January 2000 to December 2010.Results
during the study period, 307 cases of AIDS were reported among people 50 years of age or over. There was a predominance of males (205/66, 8%), mixed race, and low education levels. The municipalities with populations above 100 thousand inhabitants reported 58.5% of the cases. There was a progressive increase in cases among women; an increasing trend in the incidence (positive linear correlation); and an advance in the geographical spread of the disease, with expansion to the coastal region and to the interior of the state, reaching municipalities with populations below 30 thousand inhabitants. In some locations the risk of disease was 100 times greater than the relative risk for the state.Conclusion
aging, with the feminization and interiorization of the epidemic in adults 50 years of age and over, confirms the need for the induction of affirmative policies targeted toward this age group. 相似文献127.
Anderson Rech MS Regis Radaelli MS Adriano M. De Assis PhD João R. Fernandes MS Aline Longoni PhD Magdolna M. Vozari‐Hampe PhD Ronei S. Pinto PhD Cristiane Matté PhD 《Muscle & nerve》2014,50(1):79-86
Introduction: In this study we examined oxidative stress and skeletal muscle damage resulting from acute strength, aerobic, or concurrent exercise in rats. Methods: The animals were divided into control (C), strength (SE), aerobic (AE), and combined (CE) exercise groups. They were euthanized at 3 different time‐points (6, 24, and 48 h) after acute exercise. Results: SE exercise rats had increased dichlorofluorescein oxidation at 6 h post‐exercise and decreased superoxide dismutase activity at all time‐points. Glutathione peroxidase activity and sulfhydryl levels were increased in the AE group at 48 h post‐exercise. Serum lactate dehydrogenase activity was increased in the SE and CE groups at 24 h and in the AE group at 48 h. Echo intensity was elevated at 24 h for all groups. Conclusions: Forty‐eight hours was sufficient for complete recovery from oxidative stress and muscle damage in the SE and CE groups, but not in the AE group. Muscle Nerve 50 : 79–86, 2014 相似文献
128.
Igor F. B. Masson Bruna D. A. de Oliveira Aline Fernanda Perez Machado Thiago Saikali Farcic Ivaldo Esteves Júnior Cristiano Schiavinato Baldan 《Indian Journal of Plastic Surgery》2014,47(1):70-76
Background:
Physiotherapy in the plastic surgery post-operative (PO) is essential to provide means for an adequate and fast recovery as it restores function through the use of physiotherapeutic procedures.Aim:
The aim of the following study is to verify the effects of the association between the manual lymphatic drainage and the therapeutic ultrasound on pain, oedema and the tissue fibrosis in liposuction and lipoabdominoplasty PO.Design:
This is a clinical trial prospective.Materials and Methods:
Eighteen women aged between 18 and 60 years participated in this study, in the late PO period following lipoabdominoplasty or liposuction in the abdomen, flanks and lower trunk, which showed tissue fibrosis of the flanks and abdomen regions. They were divided into two groups: Liposuction group and lipoabdominoplasty group. A total of twelve sessions of therapeutic ultrasound followed by the manual lymphatic drainage were performed. The patients were assessed with regard to pain, oedema and tissue fibrosis in different moments: Initial assessment, during assessment and final assessment through the application of the protocol of evaluation of cysts fibrosis levels.Statistical Analysis:
The test of equality for two proportions and the confidence interval test for mean to evaluate the distribution of variables. The significance level adopted for statistical tests was 5% (P < 0.05).Results:
There was a statistically significant reduction of pain, swelling and tissue fibrosis in both groups.Conclusion:
the association between manual lymphatic drainage and the therapeutic ultrasound reduced the swelling and the tissue fibrosis and made pain disappear in liposuction and lipoabdominoplasty PO period.KEY WORDS: Oedema, lipectomy, lymphatic system, plastic, surgery, ultrasound therapy 相似文献129.
130.
Adrian B Levine Jason Peng David Farnell Mitchell Nursey Yiping Wang Julia R Naso Hezhen Ren Hossein Farahani Colin Chen Derek Chiu Aline Talhouk Brandon Sheffield Maziar Riazy Philip P Ip Carlos Parra-Herran Anne Mills Naveena Singh Basile Tessier-Cloutier Taylor Salisbury Jonathan Lee Tim Salcudean Steven JM Jones David G Huntsman C Blake Gilks Stephen Yip Ali Bashashati 《The Journal of pathology》2020,252(2):178-188
Deep learning-based computer vision methods have recently made remarkable breakthroughs in the analysis and classification of cancer pathology images. However, there has been relatively little investigation of the utility of deep neural networks to synthesize medical images. In this study, we evaluated the efficacy of generative adversarial networks to synthesize high-resolution pathology images of 10 histological types of cancer, including five cancer types from The Cancer Genome Atlas and the five major histological subtypes of ovarian carcinoma. The quality of these images was assessed using a comprehensive survey of board-certified pathologists (n = 9) and pathology trainees (n = 6). Our results show that the real and synthetic images are classified by histotype with comparable accuracies and the synthetic images are visually indistinguishable from real images. Furthermore, we trained deep convolutional neural networks to diagnose the different cancer types and determined that the synthetic images perform as well as additional real images when used to supplement a small training set. These findings have important applications in proficiency testing of medical practitioners and quality assurance in clinical laboratories. Furthermore, training of computer-aided diagnostic systems can benefit from synthetic images where labeled datasets are limited (e.g. rare cancers). We have created a publicly available website where clinicians and researchers can attempt questions from the image survey ( http://gan.aimlab.ca/ ). © 2020 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd. 相似文献