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81.
Early Transthoracic Echocardiography after Cardiac Surgery Predicts Postoperative Atrial Fibrillation
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Juan Lacalzada M.D. Ph.D. Juan José Jiménez M.D. Ph.D. José Luis Iribarren M.D. Alejandro de la Rosa M.D. Marta Martín‐Cabeza M.D. María Manuela Izquierdo M.D. Belén Marí‐López M.D. Martín Jesús García‐González M.D. Ph.D. Pablo Jorge‐Pérez M.D. Antonio Barragán M.D. Ph.D. Ignacio Laynez M.D. Ph.D. 《Echocardiography (Mount Kisco, N.Y.)》2016,33(9):1300-1308
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83.
Augusto Sola Sergio G. Golombek María Teresa Montes Bueno Lourdes Lemus‐Varela Claudia Zuluaga Fernando Domínguez Hernando Baquero Alejandro E. Young Sarmiento Diego Natta Jose M. Rodriguez Perez Richard Deulofeut Ana Quiroga Gabriel Lara Flores Mónica Morgues Alfredo García‐Alix Pérez Bart Van Overmeire Frank van Bel 《Acta paediatrica (Oslo, Norway : 1992)》2014,103(10):1009-1018
84.
Alejandro Sousa Brant A. Inman Idelfonso Piñeiro Victor Monserrat Alberto Pérez Vincente Aparici 《International journal of hyperthermia》2014,30(3):166-170
Purpose: Ths paper reports a pilot/feasibility trial of neoadjuvant hyperthermic intravesical chemotherapy (HIVEC) prior to transurethral resection of bladder tumour (TURBT) for non-muscle invasive bladder cancer (NMIBC). Materials and methods: A pilot/feasibility clinical trial was performed and 15 patients with intermediate to high-risk NMIBC received HIVEC prior to TURBT. HIVEC consisting of eight weekly instillations of intravesical MMC (80?mg in 50?mL) delivered with the novel Combat BRS® system at a temperature of 43?°C for 60?min. Treatment-related adverse effects were measured and patients were followed for 2 years for disease recurrence. Results: A total of 119 HIVEC treatments occurred. Grade 1 adverse events consisted of irritative bladder symptoms (33%), bladder spasms (27%), pain (27%), haematuria (20%) and urinary tract infection (UTI; 14%). Grade 2 adverse events were bladder calcification (7%) and reduced bladder capacity (7%). No grade 3 or higher toxicity was observed. At TURBT, eight patients (53%) were complete responders (pT0) while seven (47%) were partial responders. With a median follow-up of 29 months, the 3-year cumulative incidence of recurrence was 15%. Conclusions: The Combat BRS® system achieved target bladder temperatures and delivered HIVEC with a favourable side-effect profile. Our pilot trial also provides preliminary evidence of treatment efficacy. 相似文献
85.
Depeursinge A Vargas A Gaillard F Platon A Geissbuhler A Poletti PA Müller H 《International journal of computer assisted radiology and surgery》2012,7(1):97-110
Purpose
Clinical workflows and user interfaces of image-based computer-aided diagnosis (CAD) for interstitial lung diseases in high-resolution computed tomography are introduced and discussed. 相似文献86.
87.
Type‐specific persistence and clearance rates of HPV genotypes in the oral and oropharyngeal mucosa in an HIV/AIDS cohort
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88.
Laura R. Chen M. Mitsu Suyemoto Albarra H. Sarsour H. Alejandro Cordova Edgar O. Oviedo-Rondón H. John Barnes 《Avian pathology》2018,47(2):152-160
Osteochondrosis (OCD) results from a disturbance of endochondral ossification in articular cartilage and is an important cause of lameness in several animal species, including chickens. OCD lesions in the free thoracic vertebra (FTV) of chickens are essential to the pathogenesis of pathogenic Enterococcus cecorum. The goal of this study was to determine the prevalence of OCD in the FTV among three modern broiler chicken crosses (strains A/A, A/B, and C/C) and Athens Canadian Random Bred (ACRB) chickens, which served as the control group. The effect of sex, age, strain, body weight, and incubation temperature profile on OCD severity for each group was determined. At 2, 4, 6, and 8 weeks of age, the FTV of 10 male and 10 female birds from each strain exposed to either optimal or low-early, high-late incubation temperature profiles were collected and scored histologically for OCD lesion severity. OCD spectrum lesions were detected in >70% of all strain/sex combinations, including the ACRB controls. No association was observed between mean OCD score and broiler strain, incubation temperature profile, sex, age, or body weight. These findings indicate that OCD of the FTV is common in broiler chickens with similar prevalence observed in broilers with modern genetics and the ACRB broilers which represent 1950s broiler genetics. As the parameters examined did not have a statistical correlation with OCD, additional work is needed to understand factors that contribute to development of OCD in chickens. 相似文献
89.
José M. de la Torre Hernández Salvatore Brugaletta Joan A. Gómez Hospital José A. Baz Armando Pérez de Prado Ramón López Palop Belen Cid Tamara García Camarero Alejandro Diego Hipólito Gutiérrez José A. Fernández Diaz Juan Sanchis Fernando Alfonso Roberto Blanco Javier Botas Javier Navarro Cuartero José Moreu Francisco Bosa Antonio J. Domínguez 《Revista espa?ola de cardiología》2019,72(12):1005-1011
Background and objectivesPatients older than 75 years with ST-segment elevation myocardial infarction undergoing primary angioplasty in cardiogenic shock have high mortality. Identification of preprocedural predictors of short- and long-term mortality could be useful to guide decision-making and further interventions.MethodsWe analyzed a nationwide registry of primary angioplasty in the elderly (ESTROFA MI + 75) comprising 3576 patients. The characteristics and outcomes of the subgroup of patients in cardiogenic shock were analyzed to identify associated factors and prognostic predictors in order to derive a baseline risk prediction score for 1-year mortality. The score was validated in an independent cohort.ResultsA total of 332 patients were included. Baseline independent predictors of mortality were anterior myocardial infarction (HR 2.8, 95%CI, 1.4-6.0; P = .005), ejection fraction < 40% (HR 2.3, 95%CI, 1.14-4.50; P = .018), and time from symptom onset to angioplasty > 6 hours (HR 3.2, 95%CI, 1.6-7.5; P = .001). A score was designed that included these predictive factors (score “6-ANT-40”). Survival at 1 year was 54.5% for patients with score 0, 32.3% for score 1, 27.4% for score 2 and 17% for score 3 (P = .004, c-statistic 0.70). The score was validated in an independent cohort of 124 patients, showing 1-year survival rates of 64.5%, 40.0%, 28.9%, and 22.2%, respectively (P = .008, c-statistic 0.68).ConclusionsA preprocedural score based on 3 simple clinical variables (anterior location, ejection fraction < 40%, and delay time > 6 hours) may be used to estimate survival after primary angioplasty in elderly patients with cardiogenic shock and to guide preinterventional decision-making. 相似文献
90.