全文获取类型
收费全文 | 147562篇 |
免费 | 6178篇 |
国内免费 | 428篇 |
专业分类
耳鼻咽喉 | 2259篇 |
儿科学 | 4562篇 |
妇产科学 | 3075篇 |
基础医学 | 19569篇 |
口腔科学 | 4918篇 |
临床医学 | 9193篇 |
内科学 | 36731篇 |
皮肤病学 | 4258篇 |
神经病学 | 11922篇 |
特种医学 | 3812篇 |
外国民族医学 | 2篇 |
外科学 | 19129篇 |
综合类 | 738篇 |
一般理论 | 45篇 |
预防医学 | 13264篇 |
眼科学 | 3079篇 |
药学 | 9890篇 |
中国医学 | 658篇 |
肿瘤学 | 7064篇 |
出版年
2023年 | 958篇 |
2022年 | 902篇 |
2021年 | 3236篇 |
2020年 | 1660篇 |
2019年 | 3385篇 |
2018年 | 5631篇 |
2017年 | 3359篇 |
2016年 | 3202篇 |
2015年 | 3585篇 |
2014年 | 4217篇 |
2013年 | 6149篇 |
2012年 | 10724篇 |
2011年 | 11326篇 |
2010年 | 5823篇 |
2009年 | 4219篇 |
2008年 | 9134篇 |
2007年 | 9672篇 |
2006年 | 8994篇 |
2005年 | 8834篇 |
2004年 | 7834篇 |
2003年 | 7315篇 |
2002年 | 6937篇 |
2001年 | 3945篇 |
2000年 | 4541篇 |
1999年 | 3445篇 |
1998年 | 674篇 |
1997年 | 463篇 |
1996年 | 446篇 |
1995年 | 385篇 |
1994年 | 293篇 |
1993年 | 276篇 |
1992年 | 1329篇 |
1991年 | 1105篇 |
1990年 | 1005篇 |
1989年 | 819篇 |
1988年 | 697篇 |
1987年 | 657篇 |
1986年 | 678篇 |
1985年 | 567篇 |
1984年 | 445篇 |
1983年 | 345篇 |
1979年 | 361篇 |
1975年 | 287篇 |
1974年 | 326篇 |
1973年 | 375篇 |
1972年 | 315篇 |
1971年 | 327篇 |
1970年 | 307篇 |
1969年 | 302篇 |
1968年 | 276篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
961.
María Gutiérrez Fernández David Carrasco de Andrés Luis Miguel Salmerón Febres Lucas González Herrera Silvia Jiménez Brobeil 《Cirugía espa?ola》2021,99(1):55-61
IntroductionTo analyse the influence of socioeconomic status on the clinical profile of patients undergoing non-traumatic lower-limb amputation.MethodsRetrospective study of 697 lower-limb amputee patients in an Angiology and Vascular Surgery Department during a 5-year period. Patients were classified according to their socioeconomic status (low, medium and high). We analysed demographic (age and gender) and clinical variables (cause of amputation, comorbidity, cardiovascular risk factors and amputation level).ResultsMean age was 70.5 ± 11.9 years, and the median was 72 years. The low socioeconomic status group presented a higher frequency of amputations in men. Cardiovascular risks factors were more frequent in this socioeconomic group, and the difference was statistically significant for diabetes (85.8% low, 69.3% medium, 65% high; P<.01) and obesity (31.4% low, 22.6% medium, 12.5% high, P<.01). Diabetic retinopathy was the only comorbidity with a significant association with low socioeconomic status (21.1% low, 15.3% medium, 12.5% high, P<.03). Regarding the cause for amputation, there was no difference in terms of socioeconomic status. The low socioeconomic level showed a higher frequency of major amputation, which was a significant difference (63.6% low, 41.2% medium, 55% high, P<.04) and a higher predisposition for this amputation level.ConclusionsThe low socioeconomic status has been shown to determine an unfavourable vascular risk profile in lower-limb non-traumatic amputees and a higher predisposition of a major amputation. This socioeconomic level demonstrates a negative influence on these patients’ diabetes, obesity and diabetic retinopathy. 相似文献
962.
963.
Alba Manuel-Vázquez José Ramón Oliver-Guillén Raquel Latorre-Fragua Ana Palomares Cano Mario Serradilla Martín José Manuel Ramia 《Cirugía espa?ola》2021,99(2):124-131
IntroductionThe number of citations is considered as an indirect indicator of the merit of an article, journal or researcher, although it is not an infallible method to determine scientific quality. Our goal is to determine the characteristics of the articles most cited about pancreas and laparoscopy.MethodsWe performed a search of all articles published in any journal about pancreas and laparoscopy until September 2019 and selected the 100 most cited papers. We recorded number of citations, journal, year of publication, quartil, impact factor, institution, country, authors type of paper, type of surgery, topic and area.ResultsThe top 100 citations account 10,970 citations in total. The journal with the most articles is Surgical Endoscopy and 2007 is the year with the highest number of articles in the top 100 citations. The percentage of publications from America and Europe are similar.Case series is the most frequently paper, outcomes/morbidity is the most frequently discussed topic, and distal pancreatectomy is the most frequently type of surgery.ConclusionsThis bibliometric study on pancreas and laparoscopy is conditioned by the time factor, since laparoscopy has arrived later at pancreatic surgery, probably due to the morbidity and mortality associated with pancreatic surgery and the need for a high specialization in this field. The literature is recent and scarce. More and better-quality studies are needed in this field. 相似文献
964.
965.
966.
M. Dolores del Toro López Javier Arias Díaz José M. Balibrea Natividad Benito Andrés Canut Blasco Erika Esteve Juan Pablo Horcajada Juan Diego Ruiz Mesa Alba Manuel Vázquez Cristóbal Muñoz Casares Jose Luis del Pozo Miquel Pujol Melchor Riera Jaime Jimeno Inés Rubio Pérez Jaime Ruiz-Tovar Polo Alejandro Serrablo Alex Soriano Josep M. Badia 《Cirugía espa?ola》2021,99(1):11-26
Antibiotic prophylaxis in surgery is one of the most effective measures for preventing surgical site infection, although its use is frequently inadequate and may even increase the risk of infection, toxicities and antimicrobial resistance. As a result of advances in surgical techniques and the emergence of multidrug-resistant organisms, the current guidelines for prophylaxis need to be revised.The Sociedad Española de Enfermedades Infecciosas (Spanish Society of Infectious Diseases and Clinical Microbiology) (SEIMC) together with the Asociación Española de Cirujanos (Spanish Association of Surgeons) (AEC) have revised and updated the recommendations for antibiotic prophylaxis in surgery to adapt them to any type of surgical intervention and to current epidemiology. This document gathers together the recommendations on antimicrobial prophylaxis in the various procedures, with doses, duration, prophylaxis in special patient groups, and in epidemiological settings of multidrug resistance to facilitate standardized management and the safe, effective and rational use of antibiotics in elective surgery. 相似文献
967.
Bakarne Ugarte-Sierra Aitor Landaluce-Olavarria Isaac Cabrera-Serna Xavier Viñas-Trullen Carlo Brugiotti José Manuel Ramírez-Rodríguez Antonio Arroyo 《Cirugía espa?ola》2021,99(4):258-266
Enhanced Recovery After Surgery (ERAS) constitutes the application of a series of perioperative measures based on the evidence, in order to achieve a better recovery of the patient and a decrease of the complications and the mortality. These ERAS programs initially proved their advantages in the field of colorectal surgery being progressively adopted by other surgical areas within the general surgery and other surgical specialties. The main excluding factor for the application of such programs has been the urgent clinical presentation, which has caused that despite the large volume of existing literature on ERAS in elective surgery, there are few studies that have investigated the effectiveness of these programs in surgical patients in emergencies. The aim of this article is to show ERAS measures currently available according to the existing evidence for emergency surgery. 相似文献
968.
Cristina García-Amador Vladimir Arteaga Peralta Roberto de la Plaza Llamas Miguel Torralba Anibal Medina Velasco José Manuel Ramia 《Cirugía espa?ola》2021,99(4):282-288
BackgroundTo analyze whether clinical and analytical parameters differ according to histopathology in cases of acute appendicitis (AA).MethodsThis is a retrospective, observational study including patients (>14 years of age) admitted for suspicion of AA from 1 April 2014 to 31 July 2016. Histopathology was divided into complicated (including perforated and gangrenous AA) and uncomplicated appendicitis (phlegmonous). Sex, age, temperature of patients on admission to the Emergency Department, symptom duration, preoperative white blood cell (WBC) count, neutrophil percentage, mean platelet volume (MPV), platelet distribution width (PDW), C-reactive protein (CRP) and hospital stay were compared in the two groups.ResultsThree hundred and thirty-five patients were analyzed, and 284 were included. Appendicitis was uncomplicated in 194 (68.3%) and complicated in 90 (31.7%). Age, symptom duration, neutrophil percentage, CRP and hospital stay were higher in the complicated AA group (P < .05). The mean differences between uncomplicated and complicated AA were: age 13.2 years (95% CI: 8.2-18.2), symptom duration 14.1 hours (95% CI: 6.3-21.9), neutrophil percentage 5.0% (95% CI: 3.2-6.8), CRP 73.6 mg/l (95% CI: 50.0-97.2) and hospital stay 2.2 days (95% CI: 1.4-3.0), with p<0.05 for all these variables. A model based on the preoperative parameters (age, symptom duration, neutrophil percentage and CRP) was calculated to predict the likelihood of complicated AA. The receiver operating characteristic (ROC) of the model had an area under the curve of 0.80 (95% CI 0.75-0.85).ConclusionThis model is able to diagnose complicated AA without the need for imaging techniques, although it must be validated with prospective analysis. 相似文献
969.
970.
Carlos Jiménez Romero Laura Alonso Murillo Paula Rioja Conde Alberto Marcacuzco Quinto Óscar Caso Maestro Anisa Nutu Isabel Pérez Moreiras Iago Justo Alonso 《Cirugía espa?ola》2021,99(6):440-449
IntroductionThere is controversy regarding the ideal pancreaticojejunostomy technique after pancreaticoduodenectomy. Many authors consider the external Wirsung stenting technique to be associated with a low incidence of fistula, morbidity and mortality. We analyse our experience with this technique.Patients and methodsA retrospective analysis of the morbidity and mortality of a series of 80 consecutive patients who had been treated surgically over a 6.5-year period for pancreatic head or periampullary tumors, performing pancreaticoduodenectomy and pancreaticojejunostomy with external Wirsung duct stenting.ResultsMean patient age was 68.3 ± 9 years, and the resectability rate was 78%. The texture of the pancreas was soft in 51.2% of patients and hard in 48.8%. Pylorus-preserving resection was performed in 43.8%. Adenocarcinoma was the most frequent tumor (68.8%), and R0 was confirmed in 70% of patients. Biochemical fistula was observed in 11.2%, pancreatic fistula grade B in 12.5% and C in 2.5%, whereas the abdominal reoperation rate was 10%. Median postoperative hospital stay was 16 days, and postoperative and 90-day mortality was 2.5%. Delayed gastric emptying was observed in 36.3% of patients, de novo diabetes in 12.5%, and exocrine insufficiency in 3. Patient survival rates after 1, 3 and 5 years were 80.2, 53.6 and 19.2%, respectively.ConclusionsAlthough our low rates of postoperative complications and mortality using external Wirsung duct stenting coincides with other more numerous recent series, it is necessary to perform a comparative analysis with other techniques, including more cases, to choose the best reconstruction technique after pancreaticoduodenectomy. 相似文献