血清脂质结合唾液酸测定对肺部病变的诊断价值

本文介绍正常人113名,肺部恶性病变49例及肺部良性病变33例的血清LSA测定结果,正常人血清LSA含量平均值为0.1243±0.0358g/L。特异性97.40％,男女间无差异,48例肺癌血清LSA平均值0.2698±0.0915g/L,敏感性85.40％;33例良性病变LSA平均值0.1712±0.0767g/L,特异性78.79％。肺癌患者血清LSA较良性病变明显升高,故测定血清LSA对鉴别良恶性病变有一定价值。     

涎腺恶性肿瘤的回顾性研究

本文对52例涎腺恶性肿瘤进行了回顾性研究。52例中发生于腮腺者27例(51.9％);病理类型以腺样囊性癌和粘液表皮样癌最多见;随访2～8年,死亡19例,病死率最高者为腺癌(5/8)和鳞癌(3/5)。作者对腺样囊性癌的病理分型提出了不同看法。     

大鼠实验性脾虚证胰岛A、B和D细胞的免疫组织化学研究

用免疫组织化学ＰＡＰ法显示实验性脾虚组和正常对照组大鼠胰岛Ｂ细胞（胰岛素细胞）、Ａ细胞（胰高血糖素细胞）和Ｄ细胞（生长抑素细胞）．结果显示，实验组胰岛素分泌升高（Ｐ＜０．０１），胰高血糖素和生长抑素分泌下降（Ｐ＜０．０５）。实验结果提示大鼠胰岛Ａ、Ｂ和Ｄ细胞分泌活动的变化与脾虚证的症候可能有密切关系。     

Contact Nd:YAG laser and CO2 laser for cylindrical excision of the cervix. A comparative study.

An excess of blood loss and persistence of intraepithelial neoplasia after cervical conization occur with some frequency. Contact Nd:YAG laser conical excision of the uterine cervix is a new technique designed to remedy those problems. In this study, 36 women with histologically confirmed cervical intraepithelial neoplasia were treated with cylindrical excision of the uterine cervix with a contact Nd:YAG laser. The results were compared with those in 30 women who had similar lesions and were treated with the CO2 laser. Use of the Nd:YAG laser resulted in less intraoperative blood loss (mean +/- SD, 3.12 +/- 0.28 vs. 30.3 +/- 2.12 mL for the CO2 laser, P less than .01) and less postoperative blood loss. The volume of early bleeding was 6.23 +/- 1.21 vs. 20.13 +/- 2.24 mL for the CO2 laser (P less than .01), and that of late bleeding was 5.22 +/- 2.21 vs. 31.24 +/- 0.05 mL for the CO2 laser (P less than .01). The operative time was similarly less for the contact Nd:YAG laser (6.2 +/- 2.2 vs. 20.2 +/- 1.2 minutes for the CO2 laser, P less than .01). The dimensions of the excised specimens were similar. These findings suggest that the contact Nd:YAG laser offers distinct advantages over the CO2 laser in performing cylindrical excision of the cervix.     

Gene expression of human sperm component related to A4 amyloid precursor protein.

Monoclonal antibodies were raised against a specific human sperm protein and designated as the YWK-II mAb. The partial cDNA encoding the protein was isolated from a rat testis lambda gt11 expression library and the amino acid sequence of the protein was deduced. The cytoplasmic-transmembrane domains of the deduced protein had high homology with the A4 amyloid precursor protein of Alzheimer's disease. To evaluate the stage of spermatogenesis when the gene was expressed, single-stranded 35S-labeled RNA probes were prepared from the cDNA. By an in situ hybridization technique the mRNA for the antigen was detected in germ cells at all stages of spermatogenesis. The finding that the gene is expressed in spermatogonia suggests possible involvement in the initiation of germ cell differentiation or in the detachment of spermatogonia from the basement membrane.     

短波紫外线照射对小儿肺炎及中性粒细胞吞噬功能和IL－2的影响

用短波紫外线照射患儿腰背部皮肤辅助治疗小儿肺炎，提示紫外线治疗组与对照组相比，显著缩短患儿发热。咳嗽及肺部湿罗音消失时间（Ｐ＜０．０１）。用化学发光法测定中性粒细胞吞噬功能，治疗组患儿血液内中性粗细胞吞噬功能显著提高（Ｐ＜０．０５）。同时测定治疗组患儿血中ＩＬ－２低于对照组（Ｐ＜０．０５），并对上述结果机理进行了探讨。     

氟中毒和氟砷中毒对胃粘膜的影响

作者通过内窥镜对新疆奎屯地区氟中毒患者３５名，氟砷中毒患者３２名，对照组２５名的胃粘膜进行观察，旨在了解氟元素和砷元素对胃粘膜的影响，在３个组中慢性胃炎的炎症程度与炎症活动性有显著性差异。２个中毒组间无显著性差异。结果表明在高氟区和高氟砷区患者的胃粘膜层病理改变主要是任性氟中毒引起，单纯性砷中毒并无协同作用。     

大肝癌手术切除探讨（附16例分析）

报告16例大肝癌手术切除治疗效果，癌块直径>7cm。其中巨块型12例，癌块>10cm9例；癌块>14cm3例，均经病理证实。Ⅱ期切除3例，均经肝固有动脉结扎加插管注药化疗，肿块缩小后再手术，术后生存1年4例，2年3例，3年4例，4年1例，全组中位生存期24.1个月，并对大肝癌的手术适应证及术式选择等进行了探讨。