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991.
Nathaniel W. Jenkins James M. Parrish Benjamin C. Mayo Nadia M. Hrynewycz Thomas S. Brundage Franchesca A. Mogilevsky Joon S. Yoo Kern Singh 《European spine journal》2020,29(6):1304-1310
To evaluate specific demographic and perioperative variables associated with higher inpatient pain scores following minimally invasive transforaminal lumbar interbody fusion (MIS TLIF). Patients who underwent a single-level, primary MIS TLIF were retrospectively reviewed. Perioperative outcomes were collected, and postoperative inpatient VAS pain scores were measured. Both bivariate and stepwise multivariate Poisson regressions with robust error variance were used to assess risk factors for average inpatient pain score ≥ 5.0. A final backward stepwise regression model was created using age, gender, smoking status, diabetes status, insurance status, BMI, comorbidity burden, pedicle screw laterality, operative time, and estimated blood loss. A total of 255 patients undergoing primary, single-level MIS TLIF were included. Age less than 50 years, workers’ compensation insurance, preoperative VAS pain score ≥ 7, and operative duration ≥ 110 min were associated with greater postoperative pain. However, other variables such as gender, BMI, smoking status, comorbidity burden, diabetes status, and pedicle screw laterality were not associated with increased postoperative pain. The results of this study suggest that younger age, workers’ compensation, elevated preoperative pain scores, and longer operative times are independently associated with greater inpatient pain following TLIF. Surgeons can use this information to better assess which patients may require additional pain control following TLIF. Patient expectations of postoperative outcomes in regard to pain and recovery may also be better managed.
These slides can be retrieved under Electronic Supplementary Material. (paragraph). Then process the ppt slide as graphical image. 相似文献
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Martin Tammemagi Alex J. Ritchie Sukhinder Atkar-Khattra Brendan Dougherty Calvin Sanghera John R. Mayo Ren Yuan Daria Manos Annette M. McWilliams Heidi Schmidt Michel Gingras Sergio Pasian Lori Stewart Scott Tsai Jean M. Seely Paul Burrowes Rick Bhatia Ehsan A. Haider Stephen Lam 《Journal of thoracic oncology》2019,14(2):203-211
Objective
In lung cancer screening practice low-dose computed tomography, diameter, and volumetric measurement have been used in the management of screen-detected lung nodules. The aim of this study was to compare the performance of nodule malignancy risk prediction tools using diameter or volume and between computer-aided detection (CAD) and radiologist measurements.Methods
Multivariable logistic regression models were prepared by using data from two multicenter lung cancer screening trials. For model development and validation, baseline low-dose computed tomography scans from the Pan-Canadian Early Detection of Lung Cancer Study and a subset of National Lung Screening Trial (NLST) scans with lung nodules 3 mm or more in mean diameter were analyzed by using the CIRRUS Lung Screening Workstation (Radboud University Medical Center, Nijmegen, the Netherlands). In the NLST sample, nodules with cancer had been matched on the basis of size to nodules without cancer.Results
Both CAD-based mean diameter and volume models showed excellent discrimination and calibration, with similar areas under the receiver operating characteristic curves of 0.947. The two CAD models had predictive performance similar to that of the radiologist-based model. In the NLST validation data, the CAD mean diameter and volume models also demonstrated excellent discrimination: areas under the curve of 0.810 and 0.821, respectively. These performance statistics are similar to those of the Pan-Canadian Early Detection of Lung Cancer Study malignancy probability model with use of these data and radiologist-measured maximum diameter.Conclusion
Either CAD-based nodule diameter or volume can be used to assist in predicting a nodule's malignancy risk. 相似文献993.
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Paul H. Mayo 《Intensive care medicine》2013,39(10):1849-1850
998.
Warner JM Pelowa DB Gal D Rai G Mayo M Currie BJ Govan B Skerratt LF Hirst RG 《Epidemiology and infection》2008,136(7):965-971
The distribution of Burkholderia pseudomallei was determined in soil collected from a rural district in Papua New Guinea (PNG) where melioidosis had recently been described, predominately affecting children. In 274 samples, 2.6% tested culture-positive for B. pseudomallei. Pulsed-field gel electrophoresis using SpeI digests and rapid polymorphic DNA PCR with five primers demonstrated a single clone amongst clinical isolates and isolates cultured from the environment that was commonly used by children from whom the clinical isolates were derived. We concluded that individuals in this region most probably acquired the organism through close contact with the environment at these sites. Burkholderia thailandensis, a closely related Burkholderia sp. was isolated from 5.5% of samples tested, an observation similar to that of melioidosis-endemic areas in Thailand. This is the first report of an environmental reservoir for melioidosis in PNG and confirms the Balimo district in PNG as melioidosis endemic. 相似文献
999.
FAAH Gene Variation Moderates Stress Response and Symptom Severity in Patients with Posttraumatic Stress Disorder and Comorbid Alcohol Dependence
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