全文获取类型
收费全文 | 94246篇 |
免费 | 4663篇 |
国内免费 | 330篇 |
专业分类
耳鼻咽喉 | 1165篇 |
儿科学 | 2728篇 |
妇产科学 | 2210篇 |
基础医学 | 12999篇 |
口腔科学 | 1796篇 |
临床医学 | 7539篇 |
内科学 | 23011篇 |
皮肤病学 | 2040篇 |
神经病学 | 8465篇 |
特种医学 | 3091篇 |
外国民族医学 | 32篇 |
外科学 | 11689篇 |
综合类 | 407篇 |
一般理论 | 23篇 |
预防医学 | 8327篇 |
眼科学 | 1588篇 |
药学 | 6257篇 |
中国医学 | 257篇 |
肿瘤学 | 5615篇 |
出版年
2023年 | 559篇 |
2022年 | 1007篇 |
2021年 | 2304篇 |
2020年 | 1211篇 |
2019年 | 2030篇 |
2018年 | 4173篇 |
2017年 | 2625篇 |
2016年 | 1990篇 |
2015年 | 2141篇 |
2014年 | 2799篇 |
2013年 | 3993篇 |
2012年 | 6113篇 |
2011年 | 6184篇 |
2010年 | 3342篇 |
2009年 | 2901篇 |
2008年 | 5304篇 |
2007年 | 5417篇 |
2006年 | 5123篇 |
2005年 | 5194篇 |
2004年 | 4898篇 |
2003年 | 4599篇 |
2002年 | 4375篇 |
2001年 | 2329篇 |
2000年 | 2455篇 |
1999年 | 2009篇 |
1998年 | 680篇 |
1997年 | 464篇 |
1996年 | 451篇 |
1995年 | 394篇 |
1994年 | 337篇 |
1993年 | 313篇 |
1992年 | 1060篇 |
1991年 | 903篇 |
1990年 | 896篇 |
1989年 | 815篇 |
1988年 | 718篇 |
1987年 | 742篇 |
1986年 | 646篇 |
1985年 | 598篇 |
1984年 | 433篇 |
1983年 | 348篇 |
1982年 | 214篇 |
1979年 | 313篇 |
1978年 | 229篇 |
1977年 | 210篇 |
1974年 | 241篇 |
1973年 | 245篇 |
1972年 | 239篇 |
1971年 | 236篇 |
1969年 | 210篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
41.
Elizabeth?Sutton Julian?Bion Cassie?Aldridge Amunpreet?Boyal Janet?Willars Carolyn?TarrantEmail authorView authors OrcID profile 《BMC health services research》2018,18(1):1015
Background
The increased mortality risk associated with weekend admission to hospital (the ‘weekend effect’) has been reported across many health systems. More recently research has focused on causal mechanisms. Variations in the organisation and delivery of in-hospital care between weekends and weekdays have been identified, but this is not always to the detriment of weekend admissions, and the impact on mortality is uncertain. The insights of frontline staff and patients have been neglected. This article reports a qualitative study of patients and clinicians, to explore their views on quality and safety of care at weekends.Methods
We conducted focus groups and interviews with clinicians and patients with experience of acute medical care, recruited from three UK hospital Trusts. We analysed the data using a thematic analysis approach, aided by the use of NVivo, to explore quality and safety of care at weekends.Results
We held four focus groups and completed six in-depth interviews, with 19 clinicians and 12 patients. Four threats to quality and safety were identified as being more prominent at weekends, relating to i) the rescue and stabilisation of sick patients; ii) monitoring and responding to deterioration; iii) timely accurate management of the therapeutic pathway; iv) errors of omission and commission.Conclusions
At weekends patients and staff are well aware of suboptimal staffing numbers, skill mix and access to resources at weekends, and identify that emergency admissions are prioritised over those already hospitalised. The consequences in terms of quality and safety and patient experience of care are undesirable. Our findings suggest the value of focusing on care processes and systems resilience over the weekends, and how these can be better supported, even in the limited resource environment that exists in many hospitals at weekends.42.
Marc Martí-Pastor Angels Pont Mónica Ávila Olatz Garin Gemma Vilagut Carlos G. Forero Yolanda Pardo Ricard Tresserras Antonia Medina-Bustos Oriol Garcia-Codina Juan Cabasés Luis Rajmil Jordi Alonso Montse Ferrer 《Population health metrics》2018,16(1):14
Background
The EQ-5D has been frequently used in national health surveys. This study is a head-to-head comparison to assess how expanding the number of levels from three (EQ-5D-3L) to five in the new EQ-5D-5L version has improved its distribution, discriminatory power, and validity in the general population.Methods
A representative sample (N?=?7554) from the Catalan Health Interview Survey 2011–2012, aged ≥18, answered both EQ-5D versions, and we evaluated the response redistribution and inconsistencies between them. To assess validity of this redistribution, we calculated the mean of the Visual Analogue Scale (VAS), which measures perceived health. The discriminatory power was examined with Shannon Indices, calculated for each dimension separately. Spanish preference value sets were applied to obtain utility indices, examining their distribution with statistics of central tendency and dispersion. We estimated the proportion of individuals reporting the best health state in EQ-5D-5L and EQ-5D-3L within groups of specific chronic conditions and their VAS mean.Results
A very small reduction in the percentage of individuals with the best health state was observed, from 61.8% in EQ-5D-3L to 60.8% in EQ-5D-5L. In contrast, a large proportion of individuals reporting extreme problems in the 3 L version moved to severe problems (level 4) in the 5 L version, particularly for pain/discomfort (75.5%) and anxiety/depression (66.4%). The average proportion of inconsistencies was 0.9%. The pattern of the perceived health VAS mean confirmed the hypothesis established a priori, supporting the validity of the observed redistribution. Shannon index showed that absolute informativity was higher in the 5 L version for all dimensions. The means (SD) of the Spanish EQ-5D-3L and EQ-5D-5L indices were 0.87 (0.25) and 0.89 (0.22). The proportion of individuals with the best health state within each specific chronic condition was very similar, regardless of the EQ-5D version (≤?30% in half of the 28 chronic conditions).Conclusion
Although the proportion of individuals with the best possible health state is still very high, our findings support that the increase of levels provided by the EQ-5D-5L contributed to the validity and discriminatory power of this new version to measure health in general population, as in the national health surveys.43.
44.
45.
Jean-Claude Desport Anaïs Labrunie Pierre-Marie Preux Erell Pencreach Olivier Ziegler 《Nutrition Clinique et Métabolisme》2018,32(1):41-48
Objective and method
The French Obesity Plan enabled the creation of 37 Specialized Obesity Centers (CSOs) in 2012 to ensure a dual mission, the multidisciplinary management of severe or complex obesity and the organization of care channels in the regions. This report takes stock of the first three years of operation of the CSOs, based on the data collected by the National Observatory of CSOs (oNCSO), set up by the General Directorate of Hospitalization and Care.Results
The overall results were positive for access to paraclinical examinations, although all CSOs did not have a biphotonic absorptiometer (DEXA) or calorimetry. The CSOs were initially developing links with the 12 sectors of care studied by the oNCSO, with some weaknesses including psychiatry. The survey did not make it possible to take stock of the real numbers of the actual workforce of the CSOs, given the large number of outliers. All responding CSOs reported having obese-oriented therapeutic education programs for the medical, surgical, and pediatric sectors. The activities of CSOs in medicine, surgery, gynecology and obstetrics were heterogeneous. In 2014, about 25–30% of all bariatric surgery procedures were performed in the CSOs in France. On average, CSOs received about 2500 severely obese adult patients in day care or in-patient care for the medical sector. The results suggested a certain fragility of the pathways of obstetric gynecology and the pediatric pathways.Conclusion
This declarative survey, despite many limitations, shows however that CSOs have taken an important place in the French care system. 相似文献46.
Simon Larose Geneviève Boisclair-Châteauvert David J. De Wit David DuBois Gizem Erdem Ellen L. Lipman 《The journal of primary prevention》2018,39(3):205-228
This study examines three potential contributions (i.e., additive only, hierarchical compensatory, and hierarchical conditional) of mentor support to youth academic adjustment, taking into account interactions with support from mothers and teachers. We derived data from a larger study of the Big Brothers Big Sisters (BBBS) of Canada community mentoring program. The sample included 427 youth (average age 9.8 years; 64% girls, 56% White) who received one-to-one community-based mentoring for at least three months. We assessed perceptions of support from mothers and teachers before the match and assessed perceptions of support from mentors five times throughout the mentoring experience. Hierarchical linear regression analyses showed that mentor support predicted positive changes in youth academic adjustment (i.e., school attitude, academic self-efficacy, assistance seeking, and problem solving) mainly when mentees already reported high support from their mother. This finding clearly supports the conditional model and invites researchers to question the assumption that mentoring constitutes a corrective experience for young people (i.e., the compensatory model). BBBS agencies are strongly encouraged to involve parents in the mentoring process and to view them as experts, assets, and allies in their effort to meet the youth’s needs. 相似文献
47.
Sousa LM Nagamine HM Chaves TC Grossi DB Regalo SC Oliveira AS 《Brazilian Oral Research》2008,22(1):61-66
This study aimed to measure the active mandibular range of motion (ROM) (mouth opening: MO; right and left lateral movements: RL and LL; protrusion: P) in Brazilian children of both genders and of various ages, weights, and heights, and to establish correlations among such variables. Study subjects (n = 303) were healthy boys and girls, with ages ranging between 6 and 14 years, who were regular students of a public school in the state of S?o Paulo. Analysis of variance and intra-class correlation coefficients were considered significant for p < 0.05. Weak significant correlations were observed between mandibular ROM and age, height, and weight. No statistically significant differences (p > 0.05) were observed regarding mandibular ROM between gender groups. Mean mandibular ROM values showed significant increases (p < 0.05) in relation to age, height, and weight, except for RL (p > 0.05), in the studied age range. Significantly smaller (p < 0.05) mean mandibular ROM values were observed for the intervals of 6 and 7 years of age, 1.15-1.35 m, and 17.30-26.50 kg, in relation to the other ranges. Nonetheless, no differences were observed among mean mandibular ROM values in the ranges 8 to 12-14 years, 1.36-1.75 m, and 47-85 kg. Thus, it is suggested that weight, height, and age variables be considered when obtaining mandibular ROM values, particularly in children aged 6 to 7 years, measuring 1.15-1.35 m, and weighing between 17.3-46.5 kg. 相似文献
48.
Dimensional error in selective laser sintering and 3D-printing of models for craniomaxillary anatomy reconstruction 总被引:2,自引:0,他引:2
49.
García Calderín M Torres Lagares D Calles Vázquez C Usón Gargallo J Gutiérrez Pérez JL 《Medicina oral, patología oral y cirugía bucal》2007,12(4):E311-E316
The use of the microscope as a tool for practising Medicine, especially in surgical specialisations, has been established for decades. The microscope was first used in OdontologyDentistry back to the 1970s and 1980s, and was introduced more widely (although it was still far from being in general use) during 1990s. The purpose of this article is to describe the main applications of the microscope in OdontologyDentistry today, as well as providing odontologists and stomatologists, whether specialists or in general practice, with information about microscopic OdontologyDentistry for better patient care. This work also gives particular importance to matters needed to achieve the necessary manual dexterity to work in a magnified operating field using a surgical microscope (SM). 相似文献
50.
Vallejos-Sánchez AA Medina-Solís CE Casanova-Rosado JF Maupomé G Minaya-Sánchez M Pérez-Olivares S 《Journal of dentistry》2006,34(9):709-715
OBJECTIVE: To evaluate the likelihood of caries increment in schoolchildren, based on their prior caries experience. MATERIAL AND METHODS: We undertook a longitudinal study in 452 six-to-nine year olds between 1999 and 2001 in Mexico, with dental exams conducted by two standardized examiners (kappa>0.85). The dependent variable was the DMFT increment, dichotomized as without increment, and at least one unit of increment. Independent variables estimated caries experience at baseline. Data were analyzed using non-parametric tests and generalized linear models (log-binomial) to calculate relative risk (RR) adjusted for age and sex. RESULTS: The percentage of caries-free children diminished by 20.5% from 1999 to 2001. DMFT index increased two-fold, from 0.25+/-0.70 in 1999 to 0.77+/-1.30 in 2001 (p<0.001). The overall risk for this sample was 24%. The DMFT increment was higher (p<0.001) in children with DMFT>0 and dmft>0 in 1999 (RR=1.89, 95% CI=1.37-2.62; RR=2.71, 95% CI=1.94-3.76, respectively). The likelihood for DMFT increment from the 1999 levels was: (1) 2.78 times higher (95% CI=2.06-3.76) if schoolchildren had caries in any of the first permanent molars and (2) 1.62 times higher (95% CI=1.20-2.19) if schoolchildren were affected by high severity caries at baseline. CONCLUSIONS: Both caries prevalence and mean DMFT had significant increments in 18 months. Dental caries in the primary (dmft) and permanent (DMFT) dentitions at baseline are goods indicators of subsequent caries development in this group of children in a medium income country. This relationship became stronger when the occurrence of caries in the first permanent molars was included. 相似文献