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61.
Mohammed Dantani Adamu Caleb Mpyet Nasiru Muhammad Murtala Muhammad Umar Habila Muazu Francisca Olamiju 《Ophthalmic epidemiology》2016,23(6):63-69
ABSTRACTPurpose: To determine the prevalence of trachoma in each of the 25 local government areas (LGAs) of Niger State, Nigeria.Methods: A population-based cross-sectional survey was conducted in each Niger State LGA between March and April 2014, as part of the Global Trachoma Mapping Project (GTMP). GTMP protocols were used in planning and conduct of the surveys. Using probability proportional to size, 25 clusters were selected; in each of these clusters, 25 households were enrolled for the survey. All residents aged 1 year and older were examined by GTMP-certified graders for trachomatous inflammation – follicular (TF) and trichiasis using the World Health Organization simplified grading scheme. Additionally, we collected data on household water and sanitation facilities.Results: Only one LGA (Kontagora) had TF prevalence in 1–9-year-olds above 10%; one other LGA (Rafi) had TF prevalence between 5.0 and 9.9%. Six LGAs need trichiasis surgical services provided to achieve a prevalence of <1 case of trichiasis per 1000 total population. The proportion of households with access to improved water sources ranged from 23 to 100%, while household-level access to improved latrines ranged from 8 to 100% across the LGAs.Conclusion: The prevalence of trachoma is relatively low in most of Niger State. There is a need for community-based trichiasis surgical services in a small number of LGAs. The trachoma elimination program could engage water and sanitation agencies to augment access to improved water and sanitation facilities, for human rights reasons. Kontagora and Rafi need community-based interventions to reduce the prevalence of active trachoma. 相似文献
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64.
Mariam Abdullahi Adamu Melanie Nicole Weck Dietrich Rothenbacher Hermann Brenner 《International journal of cancer. Journal international du cancer》2011,128(7):1652-1658
Chronic atrophic gastritis (CAG) is a well‐established precursor of intestinal gastric cancer. However, data on incidence of CAG are rare, especially from population‐based studies. The aim of this analysis was to estimate the incidence of CAG in a large population‐based study among older adults from Germany and to identify major risk factors associated with its development. In the baseline and 5‐year follow‐up examinations of the ESTHER study, serological measurements of pepsinogen (PG) I and II and Helicobacter pylori antibodies were performed in 5,229 women and men, aged 50–74 years at baseline. Information on additional potential risk factors was obtained by questionnaire. CAG was defined by PGI < 70 ng/mL and PGI/PGII < 3. In total, there were 58 (1.1%) incident CAG cases. CAG incidence increased with increasing age from 0.5% in age group 50–54 years to 2.1% in age group 70–74 years. Seropositivity with H. pylori was strongly associated with CAG incidence, with adjusted odds ratios of 5.0 [95% confidence interval (CI): 1.6–15.8] and 11.3 (95% CI: 4.2–30.0) for participants with cytotoxin associated gene A (cagA) negative and cagA positive H. pylori infection at both baseline and follow‐up compared to those without H. pylori infection, respectively. Gender, education, smoking, alcohol consumption and family history of gastric cancer were not significantly associated with CAG incidence. Incidence of CAG is rather low in the German population. Older age and infection with H. pylori are key risk factors for the development of CAG. 相似文献
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Low education and lack of spousal relationship are associated with dementia in older adults with diabetes mellitus in Nigeria 下载免费PDF全文
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68.
Bartels I; Schlosser M; Bartz UG; Pauer HU 《Human reproduction (Oxford, England)》1998,13(12):3345-3346
One important aspect in the debate on the genetic risks associated with
intracytoplasmic sperm injection (ICSI) is the possible increased rate of
chromosomal abnormalities in resulting pregnancies. ICSI was performed in a
27 year old man with asthenoteratozoospermia and his 25 year old wife.
There was a spontaneous miscarriage at 9 weeks of gestation. Cytogenetic
investigation revealed trisomy 21. Analysis of two polymorphic
microsatellite markers showed that the additional chromosome was paternal.
This is in contrast to the fact that the vast majority of trisomic concepti
are maternal in origin. Identifying the parent of origin in trisomic
conceptions achieved by ICSI may reveal whether ICSI is associated with an
increased risk of paternally derived aneuploidy.
相似文献
69.
Pregnancy outcome and anti-Ro/SSA in autoimmune diseases: a retrospective cohort study 总被引:1,自引:0,他引:1
Mavragani CP; Dafni UG; Tzioufas AG; Moutsopoulos HM 《Rheumatology (Oxford, England)》1998,37(7):740-745
OBJECTIVE: In the present retrospective cohort study, the association of
anti-Ro/SSA antibody with pregnancy loss and adverse pregnancy outcome in
women with autoimmune diseases was investigated. MATERIALS AND METHODS:
Obstetric histories of 154 anti-Ro/SSA-positive women with autoimmune
diseases [78 systemic lupus erythematosus (SLE) and 76 non- SLE] were
analysed and compared to a control group of 142 anti-Ro/SSA- negative women
(71 SLE and 71 non-SLE) matched for disease diagnosis and age at the time
of anti-Ro/SSA diagnosis. Obstetric history was also obtained and analysed
from a group of healthy women, frequency matched to anti-Ro/SSA-positive
women on age at study entry. RESULTS: The rate of pregnancy loss and
adverse pregnancy outcome did not differ significantly between
anti-Ro/SSA-positive women, anti-Ro/SSA-negative women and healthy
controls. Anti-Ro/SSA-positive SLE women reported a significantly higher
rate (18.0%) of therapeutic abortions compared to anti-Ro/SSA-negative
women (5.6%, P=0.0244) and healthy controls (4.6%, P=0.0013). Anti-Ro/SSA
non-SLE-positive women reported a significantly higher rate (23.7%) of
recurrent pregnancy loss in comparison to anti- Ro/SSA-negative women
(7.04%, P=0.0063) and healthy controls (6.4%, P=0.0004). CONCLUSIONS:
Although anti-Ro/SSA antibody does not adversely affect pregnancy outcome
in SLE patients, it appears to be associated with recurrent pregnancy loss
in non-SLE patients.
相似文献
70.
Yilikal Adamu Colin Macleod Liknaw Adamu Wirtu Fikru Beyene Kidu Aida Abashawl 《Ophthalmic epidemiology》2016,23(6):70-76
ABSTRACTPurpose: Trachoma is a major cause of blindness in Ethiopia, and targeted for elimination as a public health problem by the year 2020. Prevalence data are needed to plan interventions. We set out to estimate the prevalence of trachoma in each evaluation unit of grouped districts (“woredas”) in Benishangul Gumuz region, Ethiopia.Methods: We conducted seven cross-sectional community-based surveys, covering 20 woredas, between December 2013 and January 2014, as part of the Global Trachoma Mapping Project (GTMP). The standardized GTMP training package and methodologies were used.Results: A total of 5828 households and 21,919 individuals were enumerated in the surveys. 19,583 people (89.3%) were present when survey teams visited. A total of 19,530 (99.7%) consented to examination, 11,063 (56.6%) of whom were female. The region-wide age- and sex-adjusted trichiasis prevalence in adults aged ≥15 years was 1.3%. Two evaluation units covering four woredas (Pawe, Mandura, Bulen and Dibate) with a combined rural population of 166,959 require implementation of the A, F and E components of the SAFE strategy (surgery, antibiotics, facial cleanliness and environmental improvement) for at least three years before re-survey, and intervention planning should begin for these woredas as soon as possible.Conclusion: Both active trachoma and trichiasis are public health problems in Benishangul Gumuz, which needs implementation of the full SAFE strategy. 相似文献