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31.
Noise pollution is an ever-increasing problem in modern technologicalsociety. It is well documented that repeated exposure to evenmoderate levels of noise can be injurious to health, but oftenunappreciated are the more pervasive physiological and psychologicaleffects. This review examines the questions of noise pollutionand its effects on mental health, and its relation to chronicsleep disorders and to cardiovascular problems. Although contradictionsabound in the literature, it seems clear that physiologicaland psychological adaptation to prolonged noise exposure doesnot occur. In view of these issues, the question of how thecommunity should respond to noise exposure is discussed. 相似文献
32.
Changes in local skin blood flow after prick-tests with histamine and allergen challenge were evaluated using laser doppler flowmetry. Two series of measurements were performed; each included 11 subjects with seasonal allergic rhinitis. In the first series vascular reactions were registered intermittently for a period of 6 hr. This was then repeated with additional registrations after 14 and 24 hr. Registrations were made in the skin close to where the test substances were applied which was in the area of the initial weal reaction. Pre-loaded skin-prick test needles were used for the histamine and allergen tests. Controls using 'blank' needles were also set on the same occasion. The control induced a transient increase in blood flow which had disappeared after 1 hr. After histamine challenge, the initial rapid increase in blood flow was followed by a slow return to baseline within 1 hr, and no further changes were noticed during the registration period. A different blood flow response was seen after the application of allergen. After an initial increase, the blood flow remained at this higher level for more than 6 hr. Thereafter a slow decrease towards baseline was seen within 24 hr. The pronounced difference between the histamine- and allergen-induced responses in the later part of the registrations after similar initial peak responses indicates that actions other than an initial burst of released histamine are responsible for the changes in dermal blood flow observed after allergen. Furthermore, our results suggest that an allergen challenge induces a continuous change in blood flow for up to 24 hr, rather than a biphasic response, in only some subjects which might be suspected from the visual reappearance of redness and induration of the skin which characterizes a dermal late-phase reaction. 相似文献
33.
DANIEL M. WALKER VALERIE A. YEAGER JOHN LAWRENCE ANN SCHECK MCALEARNEY 《The Milbank quarterly》2021,99(2):393
Policy Points
- Even though most hospitals have the technological ability to exchange data with public health agencies, the majority continue to experience challenges.
- Most challenges are attributable to the general resources of public health agencies, although workforce limitations, technology issues such as a lack of data standards, and policy uncertainty around reporting requirements also remain prominent issues.
- Ongoing funding to support the adoption of technology and strengthen the development of the health informatics workforce, combined with revising the promotion of the interoperability scoring approach, will likely help improve the exchange of electronic data between hospitals and public health agencies.
34.
Infantile seborrhoeic dermatitis and Pityrosporum ovale 总被引:1,自引:0,他引:1
Twenty children (mean age 9 weeks) with infantile seborrhoeic dermatitis (ISD) were investigated with cultures for bacteria, Pityrosporum ovale and other fungi, and 20 healthy children served as controls. P. ovale and Staphylococcus aureus were the dominant organisms. P. ovale was cultured in 18 of 20 infants with ISD as compared to 4 of 20 controls. S. aureus was cultured in 14 of 20 infants with ISD as compared to 1 of 20 controls. The role of S. aureus in ISD is not known, but it could be a secondary invader as is supposed in atopic dermatitis (AD). Even if P. ovale may be suspected as the aetiological agent of ISD further studies are needed to clarify the exact role of the organism in ISD. 相似文献
35.
Quinidine reduces biliary clearance of digoxin in man 总被引:3,自引:0,他引:3
B. ANGELIN ANNIE ARVIDSSON R. DAHLQVIST ANN HEDMAN KARIN SCHENCK-GUSTAFSSON 《European journal of clinical investigation》1987,17(3):262-265
Quinidine is known to reduce the renal clearance of digoxin, but this effect does not completely explain the influence of quinidine on the total clearance of digoxin. We therefore studied the effect of quinidine administration on biliary clearance of digoxin in five patients with atrial fibrillation. Biliary clearance of digoxin under steady state conditions before and during treatment with quinidine was investigated using a duodenal-marker-perfusion technique. Quinidine caused an average 42% (range 21-65%, P less than 0.02) reduction of the measured biliary clearance of digoxin. We conclude that the biliary effect adds to the previously demonstrated inhibitory effect of quinidine on the renal clearance of digoxin and helps to explain the decrease in total clearance of the drug. This is the first demonstration in man of a pharmacokinetic drug interaction at the level of biliary excretion. 相似文献
36.
LAWRENCE A. NAIR RUTH ANN GREENFIELD MICHAEL YARGER CARLETON NIBLEY J. MARCUS WHARTON 《Pacing and clinical electrophysiology : PACE》1997,20(10):2500-2503
During testing of a CPI model 1715 ICD, an apparent sensing abnormality was noted following shock delivery for VF. Close inspection of the recording prior to the defib-rillation attempt revealed that the surface leads spontaneously lost 848 ms of data while the event marker was unaffected. Computer simulations revealed that an inadequate buffer size for the ampHfied (surface ECC) data was the likely source of data loss. It is important to recognize tbat a discordance between surface leads and event marker may represent an abnormality in tlie data acquisition system and simulate an ICD or lead malfunction. 相似文献
37.
KAZUYOSHI SUENARI M.D. YU‐FENG HU M.D. HSUAN‐MING TSAO M.D. CHING‐TAI TAI M.D. CHERN‐EN CHIANG M.D. YENN‐JIANG LIN M.D. SHIH‐LIN CHANG M.D. LI‐WEI LO M.D. TUAN TA‐CHUAN M.D. PI‐CHANG LEE M.D. NGUYEN HUU TUNG M.D. SHIH‐YU HUANG M.D. TSU‐JUEY WU M.D. SHIH‐ANN CHEN M.D. 《Journal of cardiovascular electrophysiology》2010,21(10):1114-1119
Gender Differences in Patients With AVNRT. Introduction: The detailed electrophysiological characteristics of the gender differences associated with atrioventricular nodal reentrant tachycardia (AVNRT) have not been clarified. This study investigated the gender‐related electrophysiological differences in a large series of patients undergoing radiofrequency catheter ablation. Methods and Results: A total of 2,088 consecutive AVNRT patients (men/women 869/1,219) who underwent catheter ablation were enrolled in this study. We evaluated the gender differences in their electrophysiological characteristics. Women had a significantly younger age of onset, higher incidence of multiple jumps, shorter AH interval, atrial effective refractory period (ERP), anterograde fast pathway ERP, anterograde slow pathway ERP, and retrograde slow pathway ERP, and longer ventricular ERP than men. The incidence of baseline ventriculoatrial dissociation was lower in women than in men. Women needed less isoproterenol/atropine to induce AVNRT. No gender differences in the radiation exposure time, procedure time, complication rate, acute success rate, or second procedure rate were noted. Both typical and atypical AVNRT were more predominant in women. In the patients with atypical AVNRT, there was no significant gender difference in incidence of baseline ventriculoatrial dissociation; however, the retrograde slow pathway ERP was significantly shorter in women than in men. Women of premenopausal age (≤50 years old) had a significantly higher incidence of anterograde multiple jumps and a retrograde jump phenomenon, and a shorter anterograde slow pathway ERP and retrograde slow pathway ERP than those of women over 50 years old. Conclusion: Gender differences in the anterograde and retrograde AV nodal electrophysiology were noted in the patients with AVNRT. (J Cardiovasc Electrophysiol, Vol. 21, pp. 1114‐1119) 相似文献
38.
39.
PATRICK LOCKIE FRACO FRACS LAU KWOK LEONG BSc DAPE ANN LOUIS BSc 《Clinical & experimental ophthalmology》1986,14(1):49-53
A retrospective analysis of 80 cases of gonococcal ophthalmia revealed six (7.5%) to be due to penicillinase-producing Neisseria gonorrhoeae (PPNG), five neonatal cases and one adult. All six cases were finally cured, but best results were obtained with topical chloramphenicol and single-dose spectinomycin (40 mg/kg) given intramuscularly. All gonococcal isolates should be tested promptly for penicillinase production, and if this is present systemic treatment, modified to spectinomycin or penicillinase-stable cephalosporin, should be given as single-dose treatment. 相似文献
40.