复方戊二醛消毒剂性能实验

目的 :研究复方戊二醛性能。方法 :采用消毒药剂鉴定技术。结果 :消毒剂原液与菌悬液作用 3 0min ,对枯草杆菌黑色变种芽胞的杀灭率为 1 0 0 %。含戊二醛 1 5%的复方消毒剂于 57℃下放置 1 4d ,戊二醛浓度仅降至 1 4 7%。其原液对碳钢与铜基本无腐蚀 ,对铝有轻度腐蚀 ,对家兔皮肤无明显刺激作用。结论 :复方戊二醛消毒剂性能良好 ,可以应用于临床     

知信行结合专业心理辅导应用于宫腔镜检查术的价值

目的 探讨知信行结合专业心理辅导应用于宫腔镜检查术的价值.方法 选取2019年1月—2020年12月医院接受宫腔镜检查术的124例患者作为研究对象,按照组间基本特征具有可比性的原则分为对照组和观察组,每组62例.对照组围术期给予常规护理,观察组则在对照组基础上给予知信行结合专业心理辅导,对两组患者围术期舒适度、主观感受...     

恩度加化疗联合局部热疗治疗恶性腹腔积液临床观察

目的观察腹腔灌注重组人血管内皮抑制素注射液(恩度)加化疗联合局部热疗治疗恶性腹腔积液的近期疗效和安全性。方法经病理组织学或细胞学检查确诊的恶性腹腔积液患者53例(胃癌31例、结肠癌10例、直肠癌12例),分治疗组(A)25例和对照组(B)28例,A、B两组腹腔均灌注化疗联合局部热疗;A组腹腔加用恩度,比较两组临床近期疗效、生活质量及不良反应。结果 A组总有效率为76.0%,B组为57.1%,两组近期疗效差异有统计学意义(P<0.05)。A、B两组行为状态评分(KPS)改善率分别为72.0%和57.1%,两组比较差异有统计学意义(P<0.05);临床症状改善明显而治疗相关不良反应不明显。结论腹腔恩度加用化疗联合局部热疗治疗恶性腹腔积液近期疗效显著且安全,能提高患者的生活质量,值得临床上推广应用和进一步研究。     

1976—2009年上海市金山区居民期望寿命变迁分析

期望寿命是反映一国家或地区社会卫生发展状况和居民健康水平的综合指标。我们通过分析1976--2009年上海市金山区居民期望寿命的变化,揭示金山居民期望寿命变化规律及造成寿命损失主要疾病谱的变化情况,从而为了解30多年间金山居民健康状况发展变化情况,进而为卫生行政部门制定公共卫生政策提供背景资料和决策依据。     

妊娠同族免疫性肝病-新生儿血色病1例报告并文献复习

目的提高对妊娠同族免疫性肝病-新生儿血色病（GALD-NH）临床特点的认识。方法对广州市妇女儿童医疗中心诊断的1例GALD-NH患儿的临床表现及尸检病理诊断过程进行回顾性分析,文献复习总结该类患儿的临床特征。结果男,生后第2 d发病,肝功能和凝血功能异常,少尿,全身水肿（大量胸腔积液、腹水）,血小板减少为主要表现,积极对症治疗无效,生后43 d死亡。尸体解剖病理诊断为急性肝功能衰竭,肝外组织（胰腺、甲状腺）铁染色阳性,肝组织膜复合攻击物C5b-9免疫组化阳性,确诊GALD-NH。系统检索中国知网、维普、万方数据库、PubMed和Web of Science数据库,检索时间均从建库至2018年12月20日,12篇英文文献。报道的89例与本文病例合并后共90例NH,表现为胎儿水肿（17例）、羊水少（21例）、宫内发育迟缓（33例）,生后出现铁代谢异常（65例）、肝功能衰竭（62例）、凝血机制异常(58例);肝外铁沉着阳性(48例),肝组织C5b-9免疫组化阳性14例;铁螯合剂+抗氧化治疗36 例,单纯IVIG治疗4例,单纯换血治疗 9 例,IVIG+换血治疗20 例,肝移植13例;死亡 55 例,存活35 例,随访28例,均预后良好。结论GALD-NH罕见,生后早期发病,以铁代谢异常、肝功能衰竭和凝血机制异常为主要表现,肝外组织铁沉着及肝活检为确诊依据,早期换血+IVIG治疗为病因治疗,病死率高,存活者预后良好。     

准分子激光治疗白癜风的临床疗效与安全性研究

Objective To assess the efficacy and safety of 308 nm excimer laser in the treatment of different types of vitiligo at different stages. Methods A total of 128 patients with vitiligo, who had 317 depigmented patches, were recruited in this study and treated with 308 nm excimer laser once a week for at least 8 weeks. The degree of repigmentation was evaluated and adverse effects were recorded at the end of every treatment and last treatment. Results All patients received efficacy and safety evaluation. Of the 317 patches, 97.5% achieved repigmentation at different degrees, 71.8% got more than 25% repigmentation, and 50.8% got more than 75% repigmentation. The degree of repigmentation increased with the number of treatments. A better response was observed in the lesions on the face and neck than those on the mink and limbs, and in short-duration (<1 year) lesions than in long-duration (≥1 year) lesions. And the lesions on extremities and mueosa showed a poorer response compared with those at other sites. There was no statistical difference in clinical efficacy between active vitiligo and stable vitiligo, or between adults and children. Moreover, the treatment was well tolerated. Conclusion 308 nm excimer laser is effective in the treatment of vitiligo with rapid onset, favorable tolerability and few adverse effects.     

准分子激光治疗白癜风的临床疗效与安全性研究

Objective To assess the efficacy and safety of 308 nm excimer laser in the treatment of different types of vitiligo at different stages. Methods A total of 128 patients with vitiligo, who had 317 depigmented patches, were recruited in this study and treated with 308 nm excimer laser once a week for at least 8 weeks. The degree of repigmentation was evaluated and adverse effects were recorded at the end of every treatment and last treatment. Results All patients received efficacy and safety evaluation. Of the 317 patches, 97.5% achieved repigmentation at different degrees, 71.8% got more than 25% repigmentation, and 50.8% got more than 75% repigmentation. The degree of repigmentation increased with the number of treatments. A better response was observed in the lesions on the face and neck than those on the mink and limbs, and in short-duration (<1 year) lesions than in long-duration (≥1 year) lesions. And the lesions on extremities and mueosa showed a poorer response compared with those at other sites. There was no statistical difference in clinical efficacy between active vitiligo and stable vitiligo, or between adults and children. Moreover, the treatment was well tolerated. Conclusion 308 nm excimer laser is effective in the treatment of vitiligo with rapid onset, favorable tolerability and few adverse effects.     

哈尔滨市2168例企事业职工中脂肪肝患病情况调查

目的 初步研究企事业职工体检人群中脂肪肝患病情况与相关因素.方法 对体检中心随机选出2 168例体检人群(均无病毒性肝炎),对其一般资料脂肪肝的患病率、血糖、血脂、肝功能进行分析.结果 2 168例受检人群中脂肪肝检出为1 147例,占52.91％.其中男性检出率为64.15％,女性检出率为33.71％.男女检出率差异有显著性(P＜0.01).脂肪肝组血糖、血脂、肝功能较正常组明显升高(P＜0.01).结论 初步结果显示哈尔滨市企事业职工体检人群中脂肪肝患病率较高,男性明显高于女性;并且脂肪肝的发生与高血糖、高血脂关系密切.丙氨酸氨基转移酶(ALT)的检测可用作脂肪肝的筛查、诊断、治疗及预后的评价指标.     

临床护理路径在治疗格林-巴利综合征的应用及效果评价

  评价临床护理路径在治疗格林-巴利综合征的应用效果。临床护理路径在格林-巴利综合征患者中应用,可有效缩短治疗时间,减少并发症,降低治疗费用,提高医疗护理质量及患者满意度。