急性氯气中毒32例临床分析

1997年9月4日晨,我市北郊顺河造纸厂储氯罐管道破裂,工业用氯大量外泄,造成附近中学及农村人群因吸入氯气急性中毒。除1例因年老体弱,原患慢性支气管炎、肺气肿而当时死亡外,其余32人急送我院抢救。现在抢救情况报告如下。 1 临床资料: 1.1 一般资料:共收治32例,有28例于发病后2～3小时入院,4例于24小时后入院。男16例,女16例,年龄11～15岁12例,16～20岁6例,41～45岁1例,46～50岁3例;50岁以上有4例。其中最小年龄为11岁,最大为65岁。职业:教师6例,学生18例,农民7例,工人1例,住院天数≤5天为12例,6～10天为14例,11～15天5例,32天1例。原患慢性支气管炎3例,慢性肝炎1例,高血压病1例。     

CT对腹膜后肿瘤的诊断体会：附13例分析

ＣＴ检查可以较清楚了解腹膜后肿瘤的大小、部位、范围，及与周围组织器官的关系，有时可提供定性依据。本文分析经手术病理证实的１３例腹膜后肿瘤ＣＴ表现，结合文献复习，以提高对腹膜后肿瘤诊断的准确性，为治疗提供更多的依据。一、资料和方法本组１３例中，男８例，...     

艾滋病毒受抗体包围仍有感染力

艾滋病毒受抗体包围仍有感染力科学家最近发现艾滋病病毒在能抑制其活力的抗体包围下仍具有感染能力，这一发现有助于解释为什么艾滋病病毒难以根除。美国弗吉尼亚英联邦大学的一个科研小组对人体淋巴结内一种称为ＦＤＣ的细胞进行了研究。这种细胞中含有大量艾滋病病毒，...     

现代传媒应慎为酒唱赞歌

酒,源起何时,出自哪个国家,目前尚无确实考证。随着时间的推移,目前,酒的品种却是日新月异的多了起来,饮酒的人更是遍布大地各个角落,或老人,或青年,或少年,或男人,或女人,其人数之多可能超过吸烟的人数。 酒对人体健康的益害如何,世人众说纷纭。 历代文人墨客极度渲染酒的兴     

受微波高频辐射人员外周血5—羟色胺含量的变化

The relationship between 5-HT contents in peripheral blood and power density among workers exposed to microwave or high frequency radiation in the workshops were studied. At the same time, systems and disorder of central nervous system and cardiovascular system were examined. The results of study showed that the average 5-HT content in whole blood for high frequency radiation exposure group was lower than that of the control, but without statistical significance. Value for the microwave exposure group was significantly lower than that of the control (P less than 0.01). The 5-HT content of mechanical maintainers exposed to microwave of high frequency radiation were all lower than the contents of their corresponding control groups (P less than 0.01). But for the mechanic operators as compared with their corresponding control, no significant difference was found (P greater than 0.05). The power density exposed by the maintainers of both tested groups were all higher than that of the operators. The 5-HT contents in the whole blood were inversely proportional to the power density of microwave and high frequency groups. The incidence of neurasthenic syndrome, unsymmetric skin temperature in both limbs and hypotension was higher in the microwave and high frequency radiation groups than that in the control group. The incidence of bradycardia and some abnormal items of electrocardiograph in the microwave group was obviously greater than that in high frequency group, which may be related to different frequency exposed for these two exposure groups. Whether it is related to the contents of 5-HT needs further investigation.     

miR-409-3p靶向癌基因ELF2抑制非小细胞肺癌细胞系A549增殖

目的观察miR-409-3p对非小细胞肺癌细胞系A549增殖的影响及其机制。方法对照组为常规条件下培养的转染阳性对照核苷酸的A549细胞寡核苷酸组。实验组在对照组的基础上采用化学合成miR-409-3p模拟物,脂质体转染构建miR-409-3p高表达A549细胞;经q PCR检测,观察2组48 h后miR-409-3p的表达; MTT法检测细胞增殖;流式细胞计量术检测细胞凋亡和周期的差异。结果 miR-409-3p模拟物转染后,A549细胞中miR-409-3p表达水平显著升高(P0. 05);细胞总凋亡比例为22. 66%±4. 61%,显著高于对照组的7. 78%±1. 95%(P0. 05); G0/G1期为40. 21%±5. 37%,显著低于对照组细胞56. 09%±5. 22%(P0. 05);双荧光报告系统表明癌基因ELF2是miR-409-3p的靶基因,过表达miR-409-3p模拟物后,内源性ELF2蛋白表达水平显著下降(P0. 05)。结论 miR-409-3p可能通过调控ELF2的转录水平抑制非小细胞肺癌细胞A549增殖并促进其凋亡。     

新洁尔灭对小白鼠抗早孕的病理组织学观察

本文报告用不同剂量的新洁尔灭和同体积生理盐水注入怀孕5天小白鼠的宫腔内,3天后杀死,观察其蜕膜、胚泡、宫内膜腺体和卵巢黄体病理学改变。实验表明:对照组无改变。实验组小白鼠的蜕膜细胞全部退变坏死。病变随着给药量的递增而渐趋严重;同时胚泡亦有退变和坏死。提示:新洁尔灭对早期妊娠小白鼠是有抗早孕效果的。根据实验结果,我们认为新洁尔灭对小白鼠抗早孕的机制,很可能是一个综合因素,有直接的,也有间接的。作者强调在抗早孕机制诸因素中,蜕膜退变坏死是一个重要的因素。