Retrospective Study on the Efficacy and Safety of Quinacrine Sterilization

Objective To observe and evaluate the efficacy and safety of quinacrine sterilization.Methods A total of 572 cases of quinacrine sterilization preformed during the 4 years from 1993to 1997in Jiangsu and Guizhou Provinces were employed in this study. The efficacy and safety of quinacrine sterilization in those case were studied and evaluated, with 588 cases of surgical sterilization performed at the same time being the control group.Results Both groups were with identical demographic and gynecological characteristics. The result of multiple decrement life table analysis showed the 12th gross cumulative failure rates for quinacrine sterilization was 3. 13% and serious side effects occurred in only 2 cases accounting for O. 35%. One was ectopic pregnancy (20 months after treatment). The other was due to anaphylaxis in 10 minutes after the second insertion). No difference in the liver and nephic functions was detected and no suspected cancer cells or cancer cells were found in the two groups. 99. 6% of the 572 women interviewed accepted the quinacrine sterilization.Conclusions Quinacrine sterilization method is with high acceptability but comparatively low effectiveness. It has been proved to be a safe method of contraception in short-term. However, the safety of long-term still needs further study.     

甲胎蛋白与肝癌关系新进展

甲胎蛋白(AFP)作为原发性肝癌较为敏感而特异的生化标志,在旰癌普查、早期诊断、疗效判断等方面发挥了重要作用。近几年还有不少新的思路,如AFP异质体用于肝癌的鉴别诊断等。然而,AFP基因表达的调控及其生物学活性十分复杂,其与肝癌发生发展之间的关系尚未完全阐明,某些基础研究的成果也亟待推广应用于临床。     

妊娠妇女血清CG及TBA测定的临床意义

采用放射免疫分析法和速率法分别测定正常组和孕妇组血清 Ｃ Ｇ、 Ｔ Ｂ Ａ 含量。结果表明： Ｃ Ｇ、 Ｔ Ｂ Ａ 在中、晚孕期显著高于正常对照组。其中 Ｃ Ｇ 在中期就存在显著差异（ Ｐ＜ ０ ．０５） ,至晚孕期差异极显著（ Ｐ＜ ０ ．０１） 。提示 Ｃ Ｇ 指标在判断肝、胆代谢功能的价值优于 Ｔ Ｂ Ａ。     

多普勒超声心动图评估左心室舒张末压的研究

目的探讨多普勒超声心动图评估左室舒张末压的有效方法与指标。方法对６８例病人采用左心导管测压及经胸多普勒超声心动图检测。结果对比研究显示,联合肺静脉与二尖瓣血流频谱分析优于二尖瓣血流频谱分析,肺静脉Ａ峰和二尖瓣Ａ峰时限差值（ＰＡｄ－Ａｄ）与左室舒张末压实测值呈最佳相关性（ｒ＝０．７２,Ｐ＜０．０１）。结论认为应用多普勒超声心动图测定ＰＡｄ与Ａｄ,并以其差值估测左室舒张末压,是一项简便、可靠的无创性评估左室舒张末压的方法。ＰＡｄ－Ａｄ≥０可作为临床判断左室舒张末压增高［≥２．０ｋＰａ（１５ｍｍＨｇ）］的一项半定量指标。     

乡镇卫生院分娩室消毒灭菌现状及对策

医院分娩室的消毒灭菌质量是预防和控制医院内感染,提高医疗质量,保障母婴安全的主要措施之一。笔者于1998年12月对20家乡镇卫生院的分娩室进行消毒灭菌现状调查。现报告如下。1 材料和方法1·1 采用自制的调查表格进行实地调查。     

胃癌与幽门螺旋杆菌感染的关系

胃癌与幽门螺旋杆菌感染的关系近年来引起了广泛的关注，是医学界的热点问题。为此笔者对本院2000年胃镜检出的71例胃癌、52例胃溃疡、36例慢性萎缩性胃炎及40例慢性浅表性胃炎共199例患者进行比较性回顾研究。旨在探讨幽门螺旋杆菌(HP)感染对胃癌发生、发展过程的影响及其临床意义。     

耳穴配合高压静电疗法治疗失眠60例

失眠中医称不寐，是以经常不能获得正常睡眠为特征的病症，病情轻重不一，给患者带来很大痛苦，用药物及其他内科治疗效果欠佳。我科1998-2002年采用耳穴配合高压静电疗法治疗失眠症，取得较好疗效，现报道如下。     

截瘫病人带尿管出院的自我管理指导

我科自2000年1月～2003年12月共收治截瘫并需带尿管出院病人60例，均对病人进行尿管的自我管理指导，收到了良好的社会效果。