比较两种脐敷疗法联合中药结肠透析对肝硬化难治性腹水诱发氮质血症的治疗效果

目的:比较两种脐敷疗法联合中药结肠透析对肝硬化难治性腹水诱发氮质血症患者的疗效.方法:将50例该病患者随机分成两组,每组25例.实验组予改良的脐敷和结肠透析疗法,对照组予传统的脐敷和结肠透析疗法.结果:实验组患者在中药结肠透析后药物保留时间、腹水消退、Cr及Bun降低、减少HRS和皮肤过敏发生率等方面均优于对照组,差异有显著性意义.结论:改良的脐敷联合中药结肠透析疗法,更有利于肝硬化难治性腹水诱发氮质血症患者的治疗,是目前较理想的治疗方法.     

Exploration on Effect and Mechanism of Suiqing Pill (髓清丸) on Tumor Angiogenesis in Nude Mouse B16 Melanoma Model

Objective: To study the effect of Suiqing Pill (SQP, 髓清丸), a TCM compound drug that can activate blood circulation and get rid of blood stasis, on angiogenesis in tumor and its possible mechanism.Method: BALB/c nude mice were inoculated with melanoma cell line R16 at right armpit subcutaneously to establish cancer spontaneous metastasis model. Levels of microvessel density (MVD), vascular endothelial growth factor (VEGF) and protein expression of matrix metalloproteinase-2 (MMP-2) in tumor tissues were observed and compared. Results: Strong expression of anti-Factor Ⅷ (FⅧ) related antigen and plentiful tumor angiogenesis were seen in model control animals, while in the high-dose and low-dose SQP treated model mice, MVD was inhibited by 33.5 % and 22.6 % respectively ( P＜0.01, P＜0.05). The strong positive protein expression of VEGF and MMP-2 in model control also reduced in the SQP treated groups. Conclusion: SQP could inhibit tumor angiogenesis, protein expression of VEGF and MMP-2 in nude mice B16 melanoma models.     

牵引加电磁波导渗药物治疗腰椎间盘突出症的观察与护理

目的探讨牵引加电磁波导渗药物治疗腰椎间盘突出症的疗效及护理方法.方法将202例腰椎间盘突出症患者随机分为治疗组103例和对照组99例,治疗纽采用牵引加电磁波导渗药物疗法,对照组单纯采用牵引治疗.结果治疗组治愈58例,显效39例,有效6例,总有效率100%.对照组治愈32例,显效30例,有效27例,总有效率89.9%,两组有显著差异(P＜0.01).结论牵引加电磁波导渗药物治疗腰椎间盘突出症疗效良好.     

中药敷脐治疗肝硬化难治性腹水的效果观察与护理

目的探讨中药敷脐治疗肝硬化难治性腹水的疗效及护理要点。方法选择100例肝硬化难治性腹水患者随机分为观察组和对照组,观察组用基础治疗及护理加中药敷脐,对照组只用基础治疗及护理。结果观察组总有效率为76%,对照组总有效率为46%(P<0.05)。结论中药敷脐及合理的护理配合对治疗肝硬化难治性腹水有明显的疗效。     

热敷法降低静滴刺五加注射液的血管刺激

目的降低刺五加注射液在输液过程中的血管刺激症状。方法观察100例静脉点滴刺五加注射液的病人,随机分为两组,每组50人,实验组病人在输液过程中采用热敷法,与对照组比较。结果实验组有血管刺激症状8例（16%）,对照组34例（68%）,经χ2检验,P〈0.001,两组比较差异具有显著性。结论热敷法能降低刺五加注射液的血管刺激症状。     

舒筋活血洗剂熏洗辅助治疗痛风性关节炎疗效观察

目的 探讨舒筋活血洗剂熏洗治疗痛风性关节炎的疗效及护理方法 .方法 将80例痛风性关节炎患者随机分为观察组和对照组各40例,两组均采用中西医治疗及饮食控制,对照组在此基础上关节处外涂扶他林乳剂,而观察组加用舒筋活血洗剂熏洗关节处.结果 观察组疗效显著优于对照组(P<0.05).结论 舒筋活血洗剂熏洗治疗痛风性关节炎疗效较好,可减轻患者痛苦,提高患者生活质量.     

Exploration on Effect and Mechanism of Suiqing Pill (髓清丸) on Tumor Angiogenesis in Nude Mouse B16 Melanoma Model

Objective: To study the effect of Suiqing Pill (SQP, 髓清丸),a TCM compound drug that can activate blood circulation and get rid of blood stasis, on angiogenesis in tumor and its possible mechanism. Method: BALB/c nude mice were inoculated with melanoma cell line B16 at right armpit subcutaneously to establish cancer spontaneous metastasis model. Levels of microvessel density (MVD), vascular endothelial growth factor (VEGF) and protein expression of matrix metalloproteinase-2 (MMP-2) in tumor tissues were observed and compared. Results: Strong expression of anti-Factor Ⅷ (FⅧ) related antigen and plentiful tumor angiogenesis were seen in model control animals, while in the high-dose and low-dose SQP treated model mice, MVD was inhibited by 33. 5% and 22. 6% respectively ( P<0. 01, P<0. 05). The strong positive protein expression of VEGF and MMP-2 in model control also reduced in the SQP treated groups. Conclusion: SQP could inhibit tumor angiogenesis, protein expression of VEGF and MMP-2 in nude mice B     

针刺加中药保留灌肠治疗慢性前列腺炎的观察及护理

目的 :观察针刺加中药保留灌肠治疗慢性前列腺炎的疗效。方法 :针刺治疗慢性前列腺炎 4 6例 ,针刺主穴为中极、曲骨、横骨、会阴 ,针梗疏密波加电 30min ,用前列安灌肠液保留灌肠 ,药温 39～ 4 1℃ ,直肠灌注约10 0ml,保留时间不少于 2h ,隔日治疗 1次 ,10次为一疗程 ,一疗程结束后总结疗效。结果 :经统计学处理 ,治疗前后各项评分差异有高度显著性 (P<0 0 1)。结论 :针刺加中药保留灌肠治疗慢性前列腺炎具有较好的疗效     

药膳联合生活方式干预对糖调节受损患者的影响

目的探讨中药膳食联合生活方式（糖尿病知识教育、运动、饮食、减肥等）干预对糖调节受损（IGR）患者的作用效果。方法将社区200例IGR患者随机分为三组,空白组（n=67）,予一般糖尿病教育,对照组（n=67）予生活方式指导,干预组（n=66）予生活方式指导联合中药膳食干预。18个月后比较三组IGR患者转归情况及空腹血糖（FBG）、餐后2h血糖（2hPG）及体重指数（BMI）的变化。结果空白组、对照组、干预组三组IGR患者逆转为正常血糖分别为5．97％,29．85％,59．09％;稳定在IGR阶段者分别为79．10％,64．18％,37．88％;发展为糖尿病者分别为14．93％,5．97％,3．03％;对照组、干预组与空白组比较,干预组与对照组比较差异均有统计学意义（P〈0．01）。对照组、干预组患者的FBG,2hPG及BMI与空白组比较差异均有统计学意义（P〈0．01）。结论对IGR患者,在生活方式指导的同时进行中药膳食干预,可进一步降低FBG及2hPG,并改善IGR患者的临床转归。     

门诊慢性肝炎患者的健康教育需求及干预效果评价

目的 探讨门诊慢性病毒性肝炎患者的健康教育需求和干预.方法 采用问卷对本院门诊就诊的慢性病毒性肝炎患者进行调查,在了解其对健康教育需求的基础上给予有针对性的健康教育干预.结果 干预后门诊慢性病毒性肝炎患者对肝炎相关知识的知晓率比干预前明显提高,差异有统计学意义(p<0.01).结论 根据门诊慢性病毒性肝炎患者的不同需求实施有针对性的、个性化的健康教育干预,可提高患者对肝炎相关知识的知晓率,提高患者的遵医行为,从而有利于病毒性肝炎的防治.