股骨骨折伴股血管损伤修复一例

患者男,38岁。左大腿中下段被烧红的高温钢管贯通伤2小时于1991年3月23日急诊入院。检查:左大腿中下段前内侧有一20×25cm的创面,股内侧肌外翻,与此相对应的大腿后外侧有2个直径约5.0cm的伤口。烧焦并断裂的肌组织外翻。膝     

椎弓根固定器治疗腰椎滑脱的体会

椎弓根固定器治疗腰椎滑脱的体会郭旭黄强浦涛赵莹腰椎滑脱是腰腿痛常见原因之一。我院自１９９３年５月至１９９４年１１月用椎弓根固定器（ＰＳＳＦ）治疗腰椎滑脱１０例，效果良好。报告如下：１临床资料１１一般资料１０例中男６例，女４例；年龄２４～５１岁，平均...     

经皮克氏针与空心加压螺钉治疗股骨颈骨折临床分析

股骨颈骨折是骨科临床常见病之一,多发生于老年人,由于老年人多有不同程度的骨质疏松,是引起股骨颈骨折的重要因素,可以将老年人股骨颈骨折看作为病理骨折。骨质疏松的程度对于骨折的粉碎情况及内固定的牢固与否有直接影响。患者多为老年人,体质差,多伴有其他器官慢性疾病,如果长期卧床,会增加褥疮、坠积性肺炎等并发症的发生,直接威胁患者生命,如有手术可能,应尽量早期手术治疗,减少并发症的发生。本院于2007—2009年经皮克氏针与空心加压螺钉治疗股骨颈骨折73例,取得较为满意的疗效。     

低钾型周期性瘫痪62例临床分析

目的探讨低钾型周期性瘫痪的临床特征、诊治和预防。方法回顾性分析2008年9月～2011年3月我院收治的62例低钾型周期性瘫痪患者的临床资料。结果 62例低钾型周期性瘫痪者均为散发者,以20～40岁青壮年男性为主,突发四肢迟缓性;瘫痪,近端为主,无脑神经支配肌肉损害,无意识障碍和感觉障碍,数小时至一日达高峰。结合检查发现血钾降低,心电图低钾性改变仅1例死亡,预后一般良好。结论低钾型周期性瘫痪按临床诊断标准容易诊断,病情较急重,经补钾及对症治疗,多数预后良好,不遗留后遗症,但需要注意严重的并发症,易反复发作,注意预防高危因素发生。     

腰椎间盘突出合并马尾神经损伤

腰椎间盘突出症是骨科常见病。但腰椎椎间盘突出并合马尾损伤在临床上较少见 ,却因出现鞍区感觉障碍而影响病人的生活。故应提高临床诊断和治疗 ,减少病残率。至今 ,作者收治经手术症实的腰椎间盘突出合并马尾损伤 35例 ,现报告如下 :1　临床资料1 1　一般资料　本组男 2 8例 ,女 7例。年龄 2 1～ 5 4岁 ;平均 37岁。发病诱因 :急性腰损伤 7例 ,慢性发病 5例 ,不合理治疗 (推拿、按摩 )后发病 2 3例。腰腿痛病史 8月～ 5年。1 2　临床表现　腰痛、腿痛 35例。双腿痛 30例 ,单腿痛 5例。下肢及会阴部感觉丧失 2 7例 ,下肢或鞍区感觉减退 8例…     

肾托复位对胸腰椎屈曲型骨折的临床应用

自 198 5年 1月以来 ,我院利用手术台肾托对胸腰椎屈曲型骨折进行复位92例 ,效果满意 ,现报告如下。1　临床资料　　本组 92例中男 6 4例 ,女 2 8例 ;年龄 17～ 73岁 ;受伤距复位时间 2～ 11天 ;被压缩的椎体 97个 ,Ｌ15 1个 ,Ｔ12 2 2个 ,Ｔ118个 ,Ｌ2 4个 ,Ｌ3 2个 ,Ｔ12 -Ｌ15个。其中单纯压缩 1/3椎体 2 6例 ,压缩近 1/2椎体 5 4例 ,超过 1/2椎体 12例 ,伴有附件骨折 ,椎体脱位 ,侧方压缩者19例 ,脊柱均有不同程度的成角畸形 ,其中不全性截瘫者 2例 ,下肢肌力 4级 ,伴有不同程度的感觉障碍。2　治疗方法　　患者仰卧于手术台上 ,脊柱后…     

手术治疗老年人股骨粗隆间骨折52例

1997年7月～2003年7月,我院共采取手术治疗60岁以上老年人股骨粗隆间骨折52例,疗效满意。     

羊膜间充质干细胞移植治疗急性肾损害

BACKGROUND:Recent researches have reported that bone marrow mesenchymal stem cells transplantation can be used for the treatment of acute kidney injury, and human amnion-derived mesenchymal stem cells have a good therapeutic effect in repairing other tissues and organs injury. OBJECTIVE:To investigate the effect of the human amnion-derived mesenchymal stem cells transplantation on cisplatin-induced acute kidney injury. METHODS:Human amnion-derived mesenchymal stem cells were isolated, cultured and identified in vitro. Male ICR mice were randomly divided into three groups: normal control group, model group, human amnion-derived mesenchymal stem cells group, and mices in the model group and human amnion-derived mesenchymal stem cells group were used to establish acute kidney injury models. In the human amnion-derived mesenchymal stem cells group, 0.3 mL human amnion-derived mesenchymal stem cells with the concentration of 1.0×1010/L were injected into the mice via tail vein at 8 days; mice in the model group and normal control group were injected with normal saline in the same dose. RESULTS AND CONCLUSION:At 17 days after the establishment of cisplatin-induced acute kidney injury model by human amnion-derived mesenchymal stem cells transplantation, renal function examination results demonstrated that compared with model group, the blood urea nitrogen and serum creatinine levels in human amnion-derived mesenchymal stem cells group were significantly increased, and reached to the levels in normal control group. Hematoxylin-eosin staining results showed the clear and complete renal organizational structure with rich tubules in the human amnion-derived mesenchymal stem cells group, the integrity and structure were similar to those of the mice in the normal control group, but the pathological changes of the human amnion-derived mesenchymal stem cells group were significantly improved when compared with model group. At 7 days after human amnion-derived mesenchymal stem cells transplantation, double labeling immunofluorescence results showed there was a large number of humanamnion-derived mesenchymal stem cells colonization and distributionin in the nephridial tissue, a few MAB1281-FITC positive cells derived from human amnion-derived mesenchymal stem cells also found in the epithelium of kidney tubules. The human amnion-derived mesenchymal stem cells transplantation could promote the recovery of acute kidney injury.     

小腿离断后高渗碱性海水损伤治疗分析

我院１９８９年以来，收治１０例小腿绞轧性离断被高渗碱性海水浸泡损伤，经再植术，成活９例，失败１例，报告如下：１临床资料１１一般资料本组全为男性渔民，年龄１９～４５岁。致伤原因：全系海上捕鱼作业时小腿或踝部被渔船上拖网绳绞轧撕脱伤，且伤后瞬间伤员被拉...     

重组人Ⅱ型肿瘤坏死因子受体－抗体融合蛋白治疗类风湿关节炎

目的观察重组人Ⅱ型肿瘤坏死因子受体一抗体融合蛋白（rhTNFR：Fc）对类风湿关节炎（rheumatoid arthfitis,RA）患者的治疗效果。方法将40例活动性类风湿关节炎患者随机分为试验组和对照组。对照组20例,受试者每周口服2次甲氨蝶呤（MTX）（7．5mg/次）;治疗纽20例,受试者每周口服2次MTX（7．5mg／次）,同时每周2次皮下注射重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白（25mg／次）。连续用药12周。观察药物对类风湿关节炎炎症活动指标的影响。结果治疗组RA症状及病情活动的指标在2周起即有明显的下降,起效速度较对照组有明显优势。结论重组人Ⅱ型肿瘤坏死因子受体一抗体融合蛋白与MTX连用能较好的降低RA症状及病情活动的指标,比单用MTX效果好。