超声诊断胎儿囊状淋巴管瘤1例

孕妇 23岁.第1胎孕5月超声检查,超声检查所见:宫内孕单胎,胎儿头颅光环完整,脊柱排列规整,胎心搏动良好,双顶径5.1cm,胎儿头颈部及胸腹部可见数个囊性包块,壁薄 ,较大者约为9.8cm×5.4cm,内有分隔,胎儿腹腔可见液性暗区,最深处为 2.3cm,可见肠管漂浮(图1),超声诊断:①宫内孕单活胎;②胎儿畸形:囊状淋巴管瘤合并腹水.次日引产,病理证实为淋巴管瘤.     

35例巴德补片在腹股沟疝修补术中的应用体会

腹股沟疝的手术修补,以往我院大多采用传统的方法,如Bassini法、Halstod法等,存在手术较为繁杂、恢复慢而且复发率高等缺点。自2005年以来我院开展疝环填充式无张力疝修补术     

输尿管囊肿的超声诊断

输尿管囊肿系输尿管先天性发育异常,临床并不少见,我们用超声诊断8例,均经手术及病理证实。报告如下。     

pT1期肺腺癌间质浸润的分级及预后意义

Objective To study the prognostic significance of grading system for stromal invasion in pathologic tumor stage Tl (pTl) adenocarcinoma of lung.Methods Eighty-five cases of surgically resected pTl lung adenocarcinoma with clinicopathologic and follow-up data were retrospectively reviewed.The degree of invasive growth was classified into three grades according to its location in the tumor.The clinicopathologic characteristics and prognostic significance were analyzed.Results Amongst the 85 cases studied,17 cases (20% ) were in grade 1,12 (14% ) in grade 2 and 56 (66% ) in grade 3.The tumor size was smaller and lymphovascular permeation was less frequently encountered in cases with grade 1 stromal invasion than in those with grade 3 (P =0.005 for tumor size and P =0.018 for occurrence of lymphovascular permeation).The rate of lymph node metastasis and pathologic staging in cases with grade 1 and grade 2 were similar and were significantly lower than those with grade 3 ( P = 0.007 for rate of lymph node metastasis in grade 1 versus grade 3 tumors,P = 0.002 for pathologic stage in grade 1 versus grade 3 tumors,P = 0.027 for rate of lymph node metastasis in grade 2 versus grade 3 tumors and P =0.021 for pathologic stage in grade 2 versus grade 3 tumors).There was no statistically significant difference with respect to age,gender and smoking history of the patients,amongst cases in different grades.The overall five-year survival rate was 63%.The five-year survival rates for cases with grade 1,grade 2 and grade 3 were 100% ,83.3% and 46.6% ,respectively.The difference between cases with grade 2 and grade 3 was statistically significant (P =0.027).The death rate during follow-up for cases with grade 1,grade 2 and grade 3 were 0,16.7% and 42.9% ,respectively.The difference between cases with grade 1 and grade 3 was statistically significant ( P - 0.001).Univariate analysis showed that grade of stromal invasion (P = 0.001),pathologic stage (P<0.001),presence of lymphovascular permeation (P < 0.001) and lymph node involvement　(P < 0.001) represented important prognostic factors.Multivariate analysis also showed that pathologic stage (P <0.001) was an independent prognostic factor.Conclusions The grading system of stromal invasion in pulmonary adenocarcinoma correlates with tumor prognosis and other prognostic factors.It represents a useful criterion in prognostic categorization of pTl adenocarcinoma of lung.     

光棒在困难气道患者经鼻气管插管中的应用

目的探讨光棒在困难气道患者经鼻气管插管中的应用效果。方法选取困难气道且拟行经鼻气管插管患者131例,男62例,女69例,年龄18～60岁,ASAⅠ或Ⅱ级,采用随机数字表法分为纤维支气管镜组(F组,n=66)和光棒组(L组,n=65)。比较两组插管成功率、插管时间及术后插管并发症发生率。结果与F组比较,L组第一次插管成功率[54(83.1%)vs 57(86.4%)]差异无统计学意义,第一次插管时间明显延长[(106.9±29.8)s vs(94.6±26.9)s,P0.05];第二次插管成功率[7(63.6%)vs 4(44.4%)]差异无统计学意义,插管时间明显缩短[(107.1±21.5)s vs(137.3±19.5)s,P0.05];插管总成功率[61(92.4%)vs 61(93.8%)]差异无统计学意义。两组患者术后并发症的发生率差异均无统计学意义。结论光棒引导是困难气道患者行经鼻气管插管时的有效技术,可以作为一个应急工具。     

新型内源性磁共振报告基因——小鼠铁蛋白基因的构建

目的 应用pcDNA3.1(-)质粒载体系统构建携带小鼠铁蛋白重链全基因质粒,并探讨铁蛋白基因作为一种新型内源性磁共振分子影像报告基因的可行性和优越性.方法 从来源于小鼠肌肉的mRNA,应用一对含有限制性内切酶Not Ⅰ和BamH Ⅰ酶切位点的引物进行逆转录聚合酶链反应(RT-PCR),扩增出铁蛋白重链全基因(Fth)片断.通过限制性内切酶Not Ⅰ和BamH Ⅰ酶切和T4连接酶的作用,将铁蛋白重链全基因插入到载体pcDNA3.1(-)中,构建铁蛋白重链全基因质粒pcDNA3.1(-)-Fth.结果 质粒pcDNA3.1(-)-Fth成功构建,符合酶切和测序鉴定结果.结论 初步构建的小鼠铁蛋白重链质粒,为进一步探讨铁蛋白基因作为一种新型内源性磁共振分子影像报告基因在细胞示综和基因显像中的应用奠定了基础.     

依托信息化全面提升医院内涵管理质量

文章通过介绍医院如何大力促进现代信息技术与医院管理手段的深度融合,达到推动了医院管理效能的优化和内涵质量的提升,医院综合影响力和行业评价稳步提升。     

预防性经皮扩张气管切开术的护理

目的：通过总结预防性经皮扩张气管切开术（PDT）围术期护理的体会,探讨该手术护理配合的重要性。方法：回顾63例行预防性PDT的口腔颌面外科恶性肿瘤患者的围术期护理经过,总结护理经验。结果：所有患者顺利完成PDT,置管成功,无窒息、误吸及出血等并发症发生。结论：做好护理配合对PDT的顺利完成至关重要。     

pT1期肺腺癌间质浸润的分级及预后意义

Objective To study the prognostic significance of grading system for stromal invasion in pathologic tumor stage Tl (pTl) adenocarcinoma of lung.Methods Eighty-five cases of surgically resected pTl lung adenocarcinoma with clinicopathologic and follow-up data were retrospectively reviewed.The degree of invasive growth was classified into three grades according to its location in the tumor.The clinicopathologic characteristics and prognostic significance were analyzed.Results Amongst the 85 cases studied,17 cases (20% ) were in grade 1,12 (14% ) in grade 2 and 56 (66% ) in grade 3.The tumor size was smaller and lymphovascular permeation was less frequently encountered in cases with grade 1 stromal invasion than in those with grade 3 (P =0.005 for tumor size and P =0.018 for occurrence of lymphovascular permeation).The rate of lymph node metastasis and pathologic staging in cases with grade 1 and grade 2 were similar and were significantly lower than those with grade 3 ( P = 0.007 for rate of lymph node metastasis in grade 1 versus grade 3 tumors,P = 0.002 for pathologic stage in grade 1 versus grade 3 tumors,P = 0.027 for rate of lymph node metastasis in grade 2 versus grade 3 tumors and P =0.021 for pathologic stage in grade 2 versus grade 3 tumors).There was no statistically significant difference with respect to age,gender and smoking history of the patients,amongst cases in different grades.The overall five-year survival rate was 63%.The five-year survival rates for cases with grade 1,grade 2 and grade 3 were 100% ,83.3% and 46.6% ,respectively.The difference between cases with grade 2 and grade 3 was statistically significant (P =0.027).The death rate during follow-up for cases with grade 1,grade 2 and grade 3 were 0,16.7% and 42.9% ,respectively.The difference between cases with grade 1 and grade 3 was statistically significant ( P - 0.001).Univariate analysis showed that grade of stromal invasion (P = 0.001),pathologic stage (P<0.001),presence of lymphovascular permeation (P < 0.001) and lymph node involvement　(P < 0.001) represented important prognostic factors.Multivariate analysis also showed that pathologic stage (P <0.001) was an independent prognostic factor.Conclusions The grading system of stromal invasion in pulmonary adenocarcinoma correlates with tumor prognosis and other prognostic factors.It represents a useful criterion in prognostic categorization of pTl adenocarcinoma of lung.     

微创内固定治疗老年股骨转子间骨折

目的：探讨微创防旋股骨近端髓内钉（PFNA）及动力髋螺钉（DHS）内固定治疗老年股骨转子间骨折的临床疗效。方法：分析2007年1月－2013年10月应用微创 PFNA 内固定治疗65例及 DHS 治疗60例老年股骨转子间骨折的病例资料,统计手术时间、出血量、并发症发生率,随访术后6月及12月 Harris 评分。结果：125例均得到随访,随访时间均为12个月。PFNA 组手术时间39．0（34．5～45．5）min（中位数（四分位间距））;DHS 组手术时间59．0（49．0～71．8）。PFNA 组术中可见的出血40．0（40．0～50）ml;DHS 组术中可见的出血370．0（330．0～777．5）ml。结论：微创PFNA 内固定治疗老年股骨转子间骨折具有微创：手术时间短、出血量少、并发症少等特点,PFNA 组 Harris 评分优良率高,近期临床疗效优良率明显优于 DHS,患者近期生活质量较 DHS 提升明显。