海水浸泡女性创伤诸多特点的调查分析

据统计,海损事故中,女性伤员达到了26%,随着女兵进入大型舰船服役,演练时将出现不同程度损伤的女性伤员[1]。有关海水浸泡女性创伤伤员的临床特点与现场救援特点报告较少[2],本研究对2008-01-02/2013-01-12月海上灾害事故救援和收治海水浸泡女性创伤伤员286例进行回顾性分析,重点对海难的发生特点、女性伤员的致伤特点、临床特点、救护特点与现状进行了分析,且提出了相应的处理措施。     

米索前列醇、B超引导在无痛人流术中的临床效果观察

目的:探讨无痛人工流产术前1h口服米索前列醇400μg、术中B超实时引导对缩短手术时间、减少术中出血、降低手术并发症的作用。方法:选择自愿人工终止妊娠的健康早孕妇女150例,随机分为米索前列醇组、米索前列醇+B超组、对照组,观察宫颈口扩张程度、手术时间、术中出血量、麻醉效果、手术并发症。结果:米索前列醇组和米索前列醇+B超组的宫颈扩张程度、麻醉效果均好于对照组(P<0.01),手术时间及术中出血量均显著减少(P<0.01),米索前列醇+B超组未发生手术并发症。结论:无痛人工流产术前1h口服米索前列醇400μg、术中B超实时引导能明显缩短手术时间、减少术中出血、降低手术并发症,值得在临床中推广。     

Fisher判别分析在预测异位妊娠中的价值探讨

Objective To discuss the value of Fisher discriminant analysis of serum progesterone and the growing rate of β-human chorionic gonadotropin in the prediction of early ectopic pregnancy. Methods 66 patients with ectopic pregnancy (11 cases were successfully treated expectantly and 55 cases were treated surgically including 40 cases of rupture of fallopian tube and 15 cases of tubal abortion) and 55 patients with intrauterine pregnancy and 50 patients with threatened abortion were chosen. Serum progesterone,β-HCG,48 hβ-HCG and the 48 h growing rate of β-HCG in each group were measured and a Fisher discriminant analysis was used. Results The serum progester-one was (30.27± 18.20) nmol/L in ectopic pregnancy group,( 108.44±23.27 ) nmol/L in intrauterine pregnancy group and (91.68±34.90) nmol/L in threatened abortion group. The first β-HCG was ( 3767.63 ± 3530.38 ) U/L in ectopie pregnancy group,(29 028.65 ± 10 874.01 )U/L in intrauterine pregnancy group and (13 457.47±16 367.65)U/L in threatened abortion group. The second β-HCG was (4349.24±3536.22)U/L in ectopic pregnancygroup,(56 139.46 ± 23 296.87 ) U/L in intrauterine pregnancy group and (23 270.63 ± 23 811.68 ) U/L in threat-ened abortion group. The growing rate of β-HCG ( β-HCG/the first serum β-HCG) was 1.29 ± 0.28 in ectopic preg-nancy group,1.93 ± 0.36 in intrauterine pregnancy group and 1.97±0.28 in threatened abortion group. There was significant difference in serum progesterone,the first β-HCG and the second β-HCG as well as the growing rate of β-HCG among the groups(P<0.05 or <0.01). Fisher discriminant analysis of combing progesterone and the growing rate of β-HCG were connected with diagnosis of ectopic pregnancy,however,the only one serum β-HCG was not con-nected with diagnosis of ectopic pregnancy. 98.5% of ectopic pregnancy,65.6% of intrauterine pregnancy and 64.0% of threatened abortion were correctly classified in the Fisher discfiminant analysis,with overall correct rate of 77.8%. Conclusion Fisher discriminant analysis of combing progesterone and the growing rate of β-HCG can bet-ter predict the early ectopic pregnancy.     

Fisher判别分析在预测异位妊娠中的价值探讨

Objective To discuss the value of Fisher discriminant analysis of serum progesterone and the growing rate of β-human chorionic gonadotropin in the prediction of early ectopic pregnancy. Methods 66 patients with ectopic pregnancy (11 cases were successfully treated expectantly and 55 cases were treated surgically including 40 cases of rupture of fallopian tube and 15 cases of tubal abortion) and 55 patients with intrauterine pregnancy and 50 patients with threatened abortion were chosen. Serum progesterone,β-HCG,48 hβ-HCG and the 48 h growing rate of β-HCG in each group were measured and a Fisher discriminant analysis was used. Results The serum progester-one was (30.27± 18.20) nmol/L in ectopic pregnancy group,( 108.44±23.27 ) nmol/L in intrauterine pregnancy group and (91.68±34.90) nmol/L in threatened abortion group. The first β-HCG was ( 3767.63 ± 3530.38 ) U/L in ectopie pregnancy group,(29 028.65 ± 10 874.01 )U/L in intrauterine pregnancy group and (13 457.47±16 367.65)U/L in threatened abortion group. The second β-HCG was (4349.24±3536.22)U/L in ectopic pregnancygroup,(56 139.46 ± 23 296.87 ) U/L in intrauterine pregnancy group and (23 270.63 ± 23 811.68 ) U/L in threat-ened abortion group. The growing rate of β-HCG ( β-HCG/the first serum β-HCG) was 1.29 ± 0.28 in ectopic preg-nancy group,1.93 ± 0.36 in intrauterine pregnancy group and 1.97±0.28 in threatened abortion group. There was significant difference in serum progesterone,the first β-HCG and the second β-HCG as well as the growing rate of β-HCG among the groups(P<0.05 or <0.01). Fisher discriminant analysis of combing progesterone and the growing rate of β-HCG were connected with diagnosis of ectopic pregnancy,however,the only one serum β-HCG was not con-nected with diagnosis of ectopic pregnancy. 98.5% of ectopic pregnancy,65.6% of intrauterine pregnancy and 64.0% of threatened abortion were correctly classified in the Fisher discfiminant analysis,with overall correct rate of 77.8%. Conclusion Fisher discriminant analysis of combing progesterone and the growing rate of β-HCG can bet-ter predict the early ectopic pregnancy.     

剖宫产疤痕部位妊娠32例临床分析

目的:探讨剖宫产疤痕部位妊娠(CSP)的临床特点和治疗方法。方法:对解放军第421医院2005年1月～2009年12月收治的32例剖宫产术后疤痕部位妊娠患者的临床资料进行回顾性分析。结果:32例患者均有停经后阴道流血史,口服米非司酮联合MTX肌注19例,MTX局部用药5例,子宫动脉栓塞治疗2例。32例中,16例经联合治疗2～3周后RI上升>0.60,血β-HCG下降>50%,自觉症状减轻或消失,血HCG下降至100 mIU/ml以下出院。超声监护下清宫10例,6例行子宫疤痕局部病灶切除。结论:早期诊断对成功救治剖宫产术后疤痕部位妊娠起着关键性的作用,超声检查可提供重要的诊断依据。应用甲氨蝶呤或配伍米非司酮治疗CSP是一种比较安全、有效的保守治疗方法。     

Fisher判别分析在预测异位妊娠中的价值探讨

Objective To discuss the value of Fisher discriminant analysis of serum progesterone and the growing rate of β-human chorionic gonadotropin in the prediction of early ectopic pregnancy. Methods 66 patients with ectopic pregnancy (11 cases were successfully treated expectantly and 55 cases were treated surgically including 40 cases of rupture of fallopian tube and 15 cases of tubal abortion) and 55 patients with intrauterine pregnancy and 50 patients with threatened abortion were chosen. Serum progesterone,β-HCG,48 hβ-HCG and the 48 h growing rate of β-HCG in each group were measured and a Fisher discriminant analysis was used. Results The serum progester-one was (30.27± 18.20) nmol/L in ectopic pregnancy group,( 108.44±23.27 ) nmol/L in intrauterine pregnancy group and (91.68±34.90) nmol/L in threatened abortion group. The first β-HCG was ( 3767.63 ± 3530.38 ) U/L in ectopie pregnancy group,(29 028.65 ± 10 874.01 )U/L in intrauterine pregnancy group and (13 457.47±16 367.65)U/L in threatened abortion group. The second β-HCG was (4349.24±3536.22)U/L in ectopic pregnancygroup,(56 139.46 ± 23 296.87 ) U/L in intrauterine pregnancy group and (23 270.63 ± 23 811.68 ) U/L in threat-ened abortion group. The growing rate of β-HCG ( β-HCG/the first serum β-HCG) was 1.29 ± 0.28 in ectopic preg-nancy group,1.93 ± 0.36 in intrauterine pregnancy group and 1.97±0.28 in threatened abortion group. There was significant difference in serum progesterone,the first β-HCG and the second β-HCG as well as the growing rate of β-HCG among the groups(P<0.05 or <0.01). Fisher discriminant analysis of combing progesterone and the growing rate of β-HCG were connected with diagnosis of ectopic pregnancy,however,the only one serum β-HCG was not con-nected with diagnosis of ectopic pregnancy. 98.5% of ectopic pregnancy,65.6% of intrauterine pregnancy and 64.0% of threatened abortion were correctly classified in the Fisher discfiminant analysis,with overall correct rate of 77.8%. Conclusion Fisher discriminant analysis of combing progesterone and the growing rate of β-HCG can bet-ter predict the early ectopic pregnancy.     

年轻妇女宫颈癌临床病理因素与预后的关系

目的 探讨年轻妇女宫颈癌的临床病理因素与预后的关系.方法 回顾分析2000年2月-2005年4月收治的≤35岁的118例宫颈癌患者的临床病理资料,随机选择同期收治的＞35岁的200例宫颈癌患者作为对照,并采用免疫组化SP法检测两组Survivin、P27蛋白表达的差异,分析比较两组的临床病理因素与预后的关系.结果 青年组早期宫颈癌(Ⅰa～Ⅱa)的比例明显高于对照组;青年组瘤体≥4 cm者所占比例明显低于对照组;青年组腺癌比例明显高于对照组;青年组的淋巴结转移率、深间质浸润和人乳头瘤病毒感染阳性率均明显高于对照组;Survivin的表达量青年组较对照组明显升高,两组以上指标间差异均有统计学意义(P＜0.05).青年组病理分级和脉管累及率与对照组比较,差异无统计学意义(P＞0.05);两组P27表达量间差异无统计学意义(P＞0.05).早期病例和中晚期病例中,青年组的5年生存率和2年复发率与对照组比较,差异均有统计学意义(P＜0.05).COX回归分析显示临床分期、宫颈间质浸润深度、组织学类型、淋巴结转移、累及脉管、Survivin表达为独立预后因素(P＜0.05).结论 35岁以下宫颈癌患者具有临床期别早、病理恶性程度低、瘤体大、腺癌比例高及易转移浸润的相对高危临床病理因素.临床分期、宫颈间质浸润深度、组织学类型、淋巴结转移、脉管累及和Survivin免疫表达是影响其预后的独立因素.     

倍美力配伍米索前列醇在绝经后妇女取环中的应用

目的:探讨倍美力和米索前列醇在绝经后妇女取环中的作用。方法:90例要求取环的绝经后妇女随机分为倍美力+米索前列醇组、米索前列醇组和对照组,观察各组宫颈软化扩张程度、手术时间、出血量和成功率。结果:倍美力+米索前列醇组和米索前列醇组、对照组比较,宫颈扩张效果好(P<0.01),手术时间短(P<0.01),出血量少(P<0.01),3组取环的成功率分别为100.00%、83.33%和60.00%。结论:绝经后妇女取环前应用倍美力和米索前列醇能有效扩张宫颈、缩短手术时间、减少术中出血,减轻患者痛苦。     

女性海水浸泡严重创伤的救治

目的掌握女性海水浸泡严重创伤特点,选择一种好的处理方法。方法 120例女性海水浸泡严重创伤患者随机分成两组,对照组60例采用常规治疗,包括现场急救、手术和纠正高渗、高钠、高氯血症、纠正酸中毒和抗感染;治疗组60例在常规治疗的基础上加地塞米松、甲状腺素片、心理干预、鲁米那（Luminal）和帕罗西汀（Paroxetine）。观察伤口感染情况和临床治疗结果,对两组结果进行比较。结果对照组伤口感染率为35.0%,格拉斯哥评分（Glasgow outcome scale,GOS）优良率为51.6%;治疗组伤口感染率为12.0%,优良率为81.7%,治疗组伤口感染率和格拉斯哥评分优良率各项指标均优于对照组（P〈0.01）。结论海水浸泡女性严重创伤具有伤因多、部位多、伤情重、创伤后应激障碍的发生率高而严重、救护与救治难度大、死、残率高的特点,救治时应进行针对性处理。     

改良式阴式次全子宫切除术疗效观察

目的 对改良式阴式次全子宫切除术(RSVH)进行临床研究,探讨其临床应用价值.方法 对224例非脱垂性子宫行RSVH,经腹次全子宫切除术(SAH)120例作为对照组比较.结果 RSVH成功率为99.6 %,膀胱损伤0.4%.两组手术时间(89.21±26.45)min,(91.56±26)min;出血量(128.47±36.32)ml、(136.26±34.71),P>0.05.术后病率、肠恢复时间、住院时间、疼痛分别为19.2%、(22.12±5.36)h、(4.59±1.75)d、45.7%及30.8%、(41.34±6.97)h、(6.49±2.13)d、86.8%,P<0.05.结论 RSVH是一种安全、有效的手术方法,优点是手术时间短,创伤小,腹部不留疤痕,术后恢复快,住院时间短.