核素骨显像诊断脊柱疾病的价值

目的：探讨核素骨显像在脊柱转移瘤及其他脊柱疾病诊断中的价值。材料和方法：104例经手术病理诊断的脊柱疾病患者行^99mTc-MDP全身骨平面显像，将显像图分为局部异常浓聚、局部异常稀疏、局部加其他部位异常浓聚或稀疏、其他部位异常浓聚或稀疏几种。结果：骨显像诊断脊柱疾病的灵敏度为：转移瘤90.6%，原发恶性肿瘤76.0%，良性肿瘤52.9%，瘤样病损85.7%，炎性病变100%，压缩性骨折100%，62.5%的转移瘤患者伴有其他部伞骨骼的异常浓聚或稀疏灶。非转移瘤的其他脊柱疾病，23.6%伴有异位异常浓聚或稀疏灶。结论：核素骨显像是诊断骨转移瘤的最佳方法。对其他脊柱疾病，骨显像可判断病灶是单发抑或多发。     

旱莲草对老年小鼠免疫功能的影响

本文通过旱莲草水煎剂对老年小鼠免疫指标的影响,探讨了旱莲草的作用机理。结果表明旱莲草水煎剂能明显提高老年小鼠脾淋巴细胞分泌巨噬细胞活化因子,但抑制 CohA 激活的淋巴细胞分泌白细胞介素Ⅱ(IL-2)和体外 DNA 的合成。揭示了旱莲草能提高巨噬细胞各噬功能的根本原因。同时本文结果还说明旱莲草对免疫系统具有双向调节作用,对指导临床用药具有重要的作用。     

老年急性心肌梗塞的临床动态心电图监测

急性心肌梗塞(AMI)心电监测是CCU监测的主要疾病,AMI死亡主要原因之一是心律失常,尤其是室性心律失常是早期死亡、骤死的原因。因此,早期发现及时治疗是刻不容缓的问题。国内外资料均证明早期发现心律失常采取果断措施是降低AMI病     

外伤性膈疝X线诊断

外伤性膈疝见于胸腹部外伤病人，较少见，易造成误诊误治，给病人造成严重后果。现报告我院经X线及手术证实病例7例。 材料与方法 均为男性，年龄27岁-57岁，均有外伤史，一例同时合并脾破裂，均发生于左侧横膈，疝入内容：7例全部为胃疝入胸腔，有2例合并结肠疝入胸腔，7例均照胸部正侧位片，2例做胃肠透视检查。     

硒对老龄雄性大鼠全血、心、肝、肾谷胱甘肽过氧化物酶的活性及LPO含量的影响

采用老龄(20～21月龄)雄性 VVi—star 大鼠,观察给予老龄雄性大鼠机体补充 Se后对全血、心、肝、肾的硒谷胱甘肽过氧化物酶(SeGSH—Px)活性和脂质过氧化物(LPO)含量的影响。结果表明、机体补充硒后可使老龄大鼠全血和上述脏器组织 SeGSH—Px 活性升高,LPO 含量降低,从而起到延缓衰老的作用。     

类鼻疽三例临床特点分析

Objective To investigate the clinical features of 3 cases of Burkholderia pseudomallei septicemia in Guangxi Province.and therefore to improve its diagnosis and treatment. Method The clinical features.treatment and prognosis of 3 cases of acute septicemic melioidosis admitted to this hospital from October 2006 to December 2008 were retrospectively analyzed. Results The 3 male patients were local farmers,with an average age of (42 ±2)years.Two of them had a history of frequent trauma and contact with polluted water.and another had a history of exposure to the dust and soil.All patients had an acute onset,manifested as septicemia with chills,high-grade fever,anemia and weight loss.At the same time,the disease was often complicated with multiple organ abscesses.The pus wag characterized by smelling like mud.One case wag manifestated with lung abscess.with right calf skin pyogenic infection,and the another case was with liver,spleen,pancreas and mediastinal abscess,and the third presented with right facial and ankle soft tissue abscess.The leukocyte counts[(11.6 ±0.5)×10~9/L]and neutrophils[(8.3±0.4)×10~9/L] in 2 patients were slightly increased,but decreased in the other patient.There were significant increase of erythrocyte sedimentation rate(63.5±2.7)mm/1 h and c-reactive protein (155 ±4)mg/L,and liver dysfunotion and elevated blood glucose occurred in 3 patients.Chest radiology and CT showed a number of patchy infiltrates,consolidation,and nodules with varying sizes in the upper lung lobes.Abscess in other organs mainly occurred in liver,spleen.and skin.The final diagnosis was confirmed as infection with Burkholderia pseudomallei by repeated blood or pus culture.The isolated Burkholderia pseudonmallei wag sensitive to carbapenem,and β-lactam+β-lactamage inhibitors.One patient was treated effectively with Imipenem,and other 2 patients with β-lactam+β-lactamage inhibitors.After 3-4 days of treatment with antibiotics,the body temperature of these patients gradually decreased,and the intravenous drug wag used as long as 4 to 8 weeks.and a total course of antibiotic therapy would continue for 4 to 6 months. Conclusions Human melioidosis exists in the south and southwest of Guangxi.Repeated blood or pus culture can confirm the diagnosis.A relatively long course of antibiotic treatment with β-lactam/β-lactamage inibitors or carbapenem is recommended.     

FC方案治疗慢性淋巴细胞白血病的临床观察

目的观察分析FC方案(氟达拉滨联合环磷酰胺)治疗慢性淋巴细胞白血病的临床疗效。方法将20例已确诊的慢性淋巴细胞白血病患者设定为治疗组,同时随机抽取20例采用CHOP方案并且已完成治疗的慢性淋巴细胞白血病患者的临床资料,该组设定为对照组。治疗组患者采用FC方案,即联合应用氟达拉滨、环磷酰胺进行化疗,对照组采用CHOP方案,即联合应用环磷酰胺、阿霉素、长春新碱、醋酸泼尼松进行化疗。对比两组患者的总有效率、并发症发生率等。结果治疗组患者总有效率达95%,高于对照组的70%。化疗后随访结果显示,对照组患者复发率高于治疗组。化疗过程中出现便秘、发热、肝功能受损、肾功能受损等不良反应情况,对照组高于治疗组,两组比较有统计学差异(P<0.05)。结论 FC方案治疗慢性淋巴细胞白血病的临床疗效较好,且不良反应较小,值得在临床上推广应用。     

论方剂的多维释义

方剂的应用和研究离不开对方剂内部药物配伍关系、配伍和方剂所治病证之间关系的探讨,由于方剂的来源众多,年代不一,医家的个人学术背景参差,立方的理论依据各具特点,实际上造成了我们在理解和运用及实验研究时对方剂构成要素及相互关系解读的非均一性,这既是中医学在发源之初就具有的特点,也是中医学繁荣发展的模式,这实际是中医学宏观、动态、系统和取类比象思维特点在实践中的具体化,表现在方剂的研究和应用方面,就是代表方剂核心内容的方义分析,多维释义是客观存在,方论众多,研究层次和角度多维,各有其长,是方剂的各家学说。方剂学的主要研究任务之一就是分析比较各家之说,博采众长,结合临床和实验,实现由博返约的升华,这是研究、学习和应用方剂所必要的态度。     

电感耦合等离子体质谱法同时测定人血中9种金属元素

目的 建立了电感耦合等离子体质谱法(ICP-MS)测定人血浆样品中微量元素的方法,确定人血中微量元素的正常参考值范围.方法 采用消化法处理样品,运用电感耦合等离子体质谱法测定小学生血浆样品中的9种微量元素.结果 分析了200份血浆样品的9种微量元素,给出了参考值范围.该方法检出限为0.003-0.19μg/L;相对标准偏差(RSD)小于4.5%;9种元素的回收率在89.6%-106.3%之间.结论 电感耦合等离子体质谱法测定全血中的金属元素简便,快速,样品用量少(血浆0.2mL),适和全血中金属元素的测定.