妊娠合并先天性肾上腺皮质增生症患者的护理

先天性肾上腺增生症(CAH),属于常染色体隐性遗传,其发生率1/10 000-12 000[1],主要为21-羟化酶缺乏.CAH女性有生育能力者仅占40%,妊娠的报道不多.     

心肌破裂、心包填塞死亡一例

病史简介张某某,女,65岁。1986年7月17日因腹痛、腹泻去本村卫生室求治,诊断为“赤痢”,给庆大、痢特灵等药,用药后症状减轻。20日4 Pm突感难受,检查:体温35℃,脉搏细弱,立即静脉推注GS25%100ml加庆大8万μ,症状稍缓解。但1h后又复原状且渐重。     

Susceptibility to Vaginal Candidiasis under Different Conditions in Mice

In order to study the susceptibility of murine vaginal mucosa to Candida albicans under different conditions, vaginal lavage fluid and vaginal tissue of mice were observed and compared between murine models with normal immune system （estrogen-treated mice） and immunosuppressed murine model, and between primary infection model of vaginal candidiasis and secondary infection one. The average level of colony forming unit （CFU） from the immuosuppressed group was higher than that from estrogen-treated group at each time point and the peak time was delayed. The differences between the two groups were statistically significant （P〈0.05） from the fourth day after inoculation. A significant difference existed in the average level of CFU between the control group and the estrogen-treated group （P〈0.05）, and between the control group and the immuosuppressed group （P〈0.01）. It was concluded that the vaginal mucosa from the immunosuppressed mice is more susceptible to Candida albicans and no difference is found in susceptibility between mice with primary infection and secondary infection.     

透明隔囊肿致精神障碍一例

患者女，３５岁，农民。１０年前因“睡眠多梦，头顶轰轰响”于外院诊断为“鼻窦炎”，服药１年后好转。２６岁结婚，生育一子。父母非近亲结婚，家族无癫痫及精神病史。经常失眠，头痛、多疑１年；自言自语、独自发笑半年；病情加重伴点头、摇头２月，外院诊断为神经症并...     

28例高危新生儿周围静脉全胃肠道外营养的应用

①目的探讨全胃肠外营养(TPN)对高危新生儿应用的临床价值。②方法全部选择周围静脉输注含有电解质、维生素、氨基酸、脂肪乳的全营养混合液。③结果应用TPN治疗的28例高危新生儿全部存活。TPN应用时间最短4d,最长14d。体重均有增加,实验室检查肝功能、GPT、BUN、肌酐、胆固醇均在正常范围,未出现与TPN有关的感染、胆汁淤积与脂肪肝等并发症。④结论静脉营养对提高高危新生儿救治成功率、改善患儿的营养状况、提高机体免疫力、提高小儿生存质量有显作用。     

转化生长因子-β1对大鼠肺成纤 维细胞Ⅰ、Ⅲ型前胶原表达的影响

Objective　To observe the effect of transforming growth factor-β₁ (TGF-β₁) on the expression of procollagen and TGF-β of rat pulmonary fibroblasts(PFbs).Methods　Northern blot analysis and immunohistochemistry were used.Results　Both mRNA and protein expression of type I, III procollagen were enhanced after TGF-β₁ treatment.The signal of TGF-β mRNA and the positive staining of TGF-β were also detected after TGF-β₁ treatment.Conclusion　TGF-β₁ could enhance the synthesis of type Ⅰ procollagen, type Ⅲ procollagen and TGF-β itself in PFbs.Therefore, it was considered that the autocrine secretion of TGF-β of pulmonary interstitial cells acted as one of the key roles to cause the progressive development of pulmonary fibrosis.     

血液透析患者动静脉内瘘狭窄行球囊扩张术后护理体会

本研究总结了30例动静脉内瘘闭塞狭管后行球囊扩张术的长期血液透析患者的护理措施,主要包括穿刺时的护理、透析中的护理、透析后的护理、以及相关健康宣教。认为经过积极有效的护理措施,能有效减少内瘘血栓形成和再次发生闭塞狭窄,可延长AVF的使用期限。     

30岁以下女性恶性肿瘤32例分析

目的研究30岁以下女性恶性肿瘤患者发病情况与流行特征。方法对我院病理科2002~2006年病理资料中的32例30岁以下女性恶性肿瘤病例进行进行统计学分析。结果2002~2006年江苏省扬州市女性恶性肿瘤年平均发病率为186.72/10万,标化发病率为153.21/10万,30岁以下女性恶性肿瘤发病率为19.23/10万,30岁以下女性恶性肿瘤以胃癌、宫颈癌、甲状腺癌、乳腺癌为主。结论30岁以下女性恶性肿瘤防治工作的重点在胃癌、宫颈癌、甲状腺癌、乳腺癌,此年龄段恶性肿瘤对女性的生命健康危害极大,肿瘤易发生早期转移。应该加强对30岁以下女性胃癌、宫颈癌、甲状腺癌、乳腺癌等主要肿瘤危险因素的研究。     

腰椎间盘突出症再手术的临床处理

目的：对腰椎间盘突出症再手术的临床处理进行探讨。方法：从2000年2月至2006年4月行腰椎间盘手术846例,椎间盘突出再手术患者24例,占2．8％。再次手术行全椎板3例,半椎板7例。扩大开窗14例。其中20例行植骨融合内固定术。结果：疗效评定标准按Macnab法：优14例,良6例,可2例,差2例。优良率83．3％。本组无硬脊膜破裂及神经根损伤并发症。结论：腰椎间盘突出症再手术多因手术并发症及继发性退变所致,再手术治疗的难点是上次手术形成的瘢痕使正常解剖结构不清,给暴露和解剖结构的确认增加了困难。再次手术将导致脊柱的稳定性进一步破坏,需行内固定和融合术。