食管癌放化疗同步治疗20例分析

中晚期食管癌在治疗中进行了多方努力疗效尚差,其主要原因是复发和转移.近年来为了更进一步提高疗效采取了放疗与化疗结合的各种方法,取得了一定疗效,本文采取效、化疗同步,对中晚期食管癌患者的病分缓解有较好效果,现予报道.     

外伤性迟发性硬膜外血肿32例分析

随着ＣＴ的广泛应用，迟发性硬膜外血肿并非罕见。我院自１９９２年５月以来，共收治此类病人３２例，占我院同期硬膜外血肿的８％。本文拟对迟发性硬膜外血肿的早期诊断和治疗进行初步探讨。１临床资料１．１一般资料本组男２３例，女９例，年龄３～６５岁。１．２受伤原...     

新酶抑制剂他唑巴坦的合成

以６－氨基青霉烷酸为原料，经１０步反应合成了他唑巴坦钠。６－ＡＰＡ经重氮化，溴化转变为６α－溴代青霉烷酸，在二苯腙存在下用过氧醋酸氧化一步生成６－α溴化青霉亚砜酸二苯甲酯，再以锌粉还原得６，６－二氢青霉亚砜酸二苯甲酯，（３）与２－巯基苯噻唑共热得氮杂环丁酮二硫化物（４），（４）用无水氯化铜反应得２β－氯甲基青霉烷酸二苯甲酯（５），（５０在ＤＭＦ中与叠氮化钠作用得混合物（６）（６）以高锰酸钾氧化后生     

某钨矿矽肺因结核死因减寿的探讨

某钨矿矽肺因结核死因减寿的探讨广东大宝山矿卫生防疫站（曲江县沙溪，５１２１２８）刘赣生，张婉，彭伟任江西西华山钨矿职工医院夏近仁，杨尊道，黎家信矽肺一旦合并结核病情加重恶化，死亡率极高￣［１］，作者曾观察分析了３０年矽肺结核与单纯矽肺的生存率￣［２］...     

急性等容血液稀释性自体输血在外科手术中的应用

目的：探讨急性等容血液稀释性自体输血在外科大手术中的应用及机制。方法：40例大手术患者随机分为观察组20例和对照组20例，观察组患者在手术前手术台上按8—12ml/kg放血并按1：0．5快速补充胶体液和晶体液，在手术将结束前把血回输。对照组按常规手术。结果：观察组患者术中术后未再输异体血，对照组20例术中均输异体血，其中8例术后再输血，2例出现输血发热反应。两组患者在术前、术后、术后第1天、术后第7天的血红蛋白差异无显著性(P＞0．05)。结论：急性等容血液稀释性自体输血在外科大手术中能节省库用血，减少血源性传播疾病，减轻患者经济负担，其疗效确切，效果好，值得推广。     

EVALUATION OF IMMUNOHISTOCHEMICAL DIAGNOSIS OF RHABDOMYOSARCOMA

Objective To evaluate the sensitivity and specificity of regularly used immunohistochemical markers, including Vimentin (Vim), Desmin (Des), Myoglobin (MG), Myosin (MS), Smooth-muscle actin (SMA) and Sarcomeric actin ( Sr-A ) , in the diagnosis of rhabdomyosarcoma (RMS). Methods After resection, 24 RMSs and other childhood tumor specimens were fixed in 10% neutral-buffered formalin and embeded in paraffin. The immunohistochemical staining was performed by LSAB procedure. Heat-induced epitope retrieval of Des, MS, Sr-A was processed in order to enhence positive rate and positive strength. Results Vim, MG, MS, Des, Sr-A, SMA were arranged in the order of sensitivity from higher to lower. About specificity, Sr-A, Des, SMA, MG, Vim standed in a sequence from higher to lower ( the data of MS is insufficient) ; Des, MG, Sr-A possessedhigher experimental efficiency, followed by SMA, Vim in a succession. Conclusion Vim and MG are of the higher sensitivity but lower specificity. On the reverse, Sr-A and Des hoM the better specificity but lower sensitivity. So the combination of multiple antibody reactions shouM be considered to improve the diagnostic ability in poorly differentiated RMS. According to the result of experimental efficiency, we suggest that the combination of Des, MG and Sr-A can make it possible to diagnose the majority of RMS clearly.