Measurement of bone mineral density in patients with type 2 diabetes mellitus

AIM：To investigate into the changes in bone mineral density (BMD) in patients with Type 2 diabetes mellitus.METHODS:BMD of lumbar vertebrae 2-4 and femur in 63 cases of patients with type 2 diabetes mellitus were measured with dual energy X-ray absorptiometry (DEXA) and were compared with age, sex and BMI-matched normal control group. RESULTS:No significant differences were found in BMD of lumbar vertebrae 2-4 in female of menopause with Type 2 diabetes mellitus(P&;gt;0.05), but BMD of total were lower than that of the controls (P&;lt;0.05), BMD of neck were significantly lower than that of the controls (P&;lt;0.01); No significant differences were found in BMD of L2-4 and femur in male of 50 years old above with Type 2 diabetes mellitus (P&;gt;0.05). CONCLUSION:BMD of Type 2 diabetes mellitus is different according to different sex,BMD of female of menopause with type 2 diabetes mellitus were descended easily,especially in areas of neck BMD, it should couse to pay attention to in order to prevent pathologic bone fracture;BMD of male of 50 years old above with Type 2 diabetes mellitus have no the obvious changes than that of the controls.     

超声探讨室间隔缺损合并动脉导管未闭的诊断方法

目的:超声探讨室间隔缺损合并动脉导管未闭(VSD PDA)患者的动脉导管未闭(PDA)显示方法.方法:超声测量41例VSD PDA和41例单纯室间隔缺损(VSD)患儿的主动脉峰值流速(Vp),平均流速(Vm),流速时间积分(VTI)和心排指数(CI).除常规在胸骨旁大动脉短轴切面探查以外,彩色多普勒超声心动图在胸骨旁肺动脉分叉切面、胸骨上主动脉弓长轴,向短轴扫查切面及剑突下主动脉短轴切面探查PDA.结果:41例VSD PDA患者检出PDA 29例,占70.73%,漏诊12例,漏诊率29.27%.VSD PDA患者的Vp、Vm、VTI和CI参数明显高于单纯VSD患者,P<0.001.4例在胸骨旁大动脉短轴切面未显示的PDA,其中2例在胸骨旁肺动脉分叉切面发现PDA,1例在胸骨上主动脉弓长轴向短轴扫查切面显示PDA,1例在剑突下主动脉短轴切面显示PDA.结论:VSD患儿主动脉Vp、Vm、VTI和CI参数增高时提示合并PDA存在.探查VSD患儿胸骨旁肺动脉分叉切面、胸骨上主动脉弓长轴向短轴扫查切面及剑突下主动脉短轴切面有助于发现PDA.     

(扌衮)法推拿流派的临床辨证施治特色

法推拿是对传统推拿手法的继承与创新。从现代病理学、解剖学、经络辨证、脊神经辨证等角度结合常见病症探讨法的临床辨证施治     

小儿急性阑尾炎临床特点分析

目的:了解小儿急性阑尾炎的临床特点。方法:回顾我院1999-2003年409例小儿急性阑尾炎患儿的住院的诊治经过。结果:急性阑尾炎且行手术409例,3岁以下30例(7.3%),6～12岁299例(73.1%)。入院腹痛者405例(99.0%),呕吐292例(71.4%),发热314例(76.8%),腹部明显压痛377例(92.2%),其中单纯性224例(54.8%),化脓性78例(19.1%),坏疽性66例(16.1%),穿孔53例(12.9%),误诊20例(4.9%),阴性切除17例(4.2%),术后并发症5例(1.2%),全部均治愈出院,无一例死亡。结论:小儿急性阑尾炎表现不典型,病情进展快、易穿孔、应早期诊断、及时手术、减少并发症。     

汤承祖先生学术经验举要

汤承祖先生(1907—),江苏南通人,出生于中医世家,祖父浣香公为民初南通名医。先生家学渊源,幼承庭训,十六岁起从祖父学习歧黄之术,长期随祖侍诊,尽得真传,并耳儒目染地受到祖父高尚医德的熏陶,与此同时,     

锌离子导入治疗慢性前列腺炎

<正> 慢性前列腺炎是成年男性的常见病和多发病, 据统计35岁以上的男性有35—40％患本病。其病因复杂,症状多样化,反复发作,病程漫长,无特效治疗,难以完全治愈,严重的危害着众多患者的身心健康,是泌尿外科的一大顽症。对慢性前列腺炎的研究,近来国外文献报告,本病的发生和发展可能与前     

NPHS1两种新突变蛋白分子的细胞内分布

目的：研究NPHS1两种新突变编码蛋白在细胞内的分布与先天性肾病综合征发病机制的关系。方法：构建野生型和两种突变型NPHS1克隆，并转染至COS7细胞内，应用免疫荧光双标记的方法，分别进行细胞内及细胞表面的荧光标记，通过共聚焦显微镜对裂隙膜分子Nephrin在细胞内的分布进行研究。结果：野生型Nephrin表现为细胞内和细胞膜染色模式；V822M和C265R则主要为细胞内内质网染色模式，细胞膜着色几乎缺失。结论：突变的Nephrin蛋白由于错误折叠，不能由内质网被输送至细胞表面，这可能是先天性肾病综合征发病的机制之一。