浅析基于健康管理的中医药健康旅游的发展策略

文章探索基于"治未病"的健康管理与中医药健康旅游的结合模式,总结归纳基于健康管理的中医药健康旅游的发展状况和存在的问题,对存在的问题以及利用现有的资源技术进行分析思考,就基于健康管理的中医药健康旅游的发展问题提出有效的解决方法、方式、途径。     

妊娠期肝内胆汁淤积症胎儿胆汁酸水平与肺表面活性物质的相关性研究

Objective To explore the relationship between total bile acid(TBA)concentration and fetal pulmonary surfactant in intrahepatic cholestasis of pregnancy(ICP).Methods Fifry five patients with ICP(ICP group)who received cesarean section from April 2008 to February 2010 in Second Xiangya Hospital,Central South University,were recruited.The general conditions of the neonates within 7 days after birth in ICP group were recorded.Those with fetal distress,neonatal asphyxia,or neonatal respiratory distress syndrome were referred as pathological neonates, others were referred as normal neonates. Over the same period, 23 healthy gravidas were recruited as control group. Enzymatic method was used to detect the TBA concentrations in maternal blood, cord blood and amniotic fluid. ELISA was employed to measure the urfactant protein A (SP-A) concentration in cord blood. High performance liquid chromatography system was used to detect the concentrations of phesphatidylcholine (PC),phosphatidylinositol (PI),lysophosphatidylcholine ( LPC), and sphingomyelin(SM) in amniotic fluid. Results ( 1 ) The concentrations of TBA in maternal blood, cord blood and amniotic fluid were ( 30. 1 ± 7.9 ), (9. 3± 3. 3 ) and (4. 4 ± 1.5 ) mmol/L in ICP group, (4. 8 ± 2. 2), (4. 9 ± 0. 9) and ( 1.4 v 1.1 ) mmol/L in control group, respectively. The differences between the two groups were significant ( P ＜ 0. 05 ). ( 2 ) The SP-A concentration in cord blood in ICP group was ( 29. 5 ± 6. 4 ) μg/L, significantly higher than that in control group, which was ( 22. 6 ± 7. 4 )μg/L ( P＜ 0. 05 ). ( 3 ) There were 20 pathological neonates and 35 normal neonates in ICP group. In pathological neonates, the concentrations of TBA and SP-A in cord blood were (10.9 ± 2.2) mmol/L,(37.0 ± 5.9 ) μg/L, respectively; and were ( 8.0 ± 2. 8 ) mmol/L, ( 26. 7 ± 4. 8 ) μg/L in normal neonates. The differences were significant (P＜ 0. 05 ). (4) There was a positive correlation between TBA concentration in cord blood and in maternal blood ( r1 = 0. 706, P＜0. 05 ). The TBA concentration in cord blood was positively correlated with SP-A concentration as well ( r3 = 0. 494,P ＜ 0. 05 ). (5) The PC and PI concentrations in amniotic fluid were (65.4 ± 7.2) mg/L and ( 3. 8 ± 0. 6 ) mg/L in ICP group, ( 69. 7 ±3.7) mg/L and (4. 3 ± 0. 7 ) mg/L in control group, respectively. The differences were significant (P ＜0. 05 ). The concentration of LPC in amniotic fluid in ICP group was (4. 8 ±0. 9) mg/L, significantly higher than that in control group (P＜0. 05), which was (4. 2 ±0. 6) mg/L. The concentration of SM in amniotic fluid was (3.5±0. 8) mg/L in ICP group, (4. 0 ± 0. 5 ) mg/L in control group, with no significant difference ( P＞0. 05 ). (6) The ratio of PC/LPC in ICP group ( 14. 2± 3. 2 ) was significantly lower than that in control group ( 16. 9 ± 2. 5 ) ( P＜ 0. 05 ). ( 7 ) The TBA concentration in cord blood was negatively correlated with PC and PI concentrations (r1 = -0. 561, r2 = -0. 407, P ＜ 0. 05 ), and had no correlation with LPC concentration (r3 = 0. 260, P＞ 0. 05). Conclusions ( 1 ) The fetal TBA concentrations in both cord blood and amniotic fluid of patients with ICP was higher than those of healthy gravidas, they were also positively correlated with maternal TBA concentration. (2) ICP resulted in the change of fetal pulmonary surfactant and this change was associated with TBA concentrations in both cord blood and amniotic fluid.     

手法推拿在肩关节周围炎中的应用

自 1998～ 2 0 0 0年 ,作者采用手法推拿治疗肩关节周围炎37例 ,取得了满意疗效。现总结报告如下。1　临床资料　　本组 37例中 ,男 6例 ,女 31例。年龄 40～ 5 5岁 ,平均 47.5岁。病程 2个月以内者 6例 ,2～ 6个月者 2 1例 ,6个月以上者 10例。单肩发病者 2 5例 ,双肩发病者 12例。有外伤史者 1例 ,有肩峰下滑囊炎、冈上肌肌腱炎、肱二头肌肌腱炎病史者 5例 ,其余 31例皆无明显诱因 ,隐匿发病。2　治疗方法患者取坐位 ,术者立于患侧 (以右侧为例 ) ,先用拿法、捏法、滚法、一指禅推法、按法施术于患侧肩部、上臂三角肌、上臂内侧、肩前部、…     

血管紧张素转换酶在子痫前期胎盘组织中的表达及活性变化

目的:探讨血管紧张素转换酶(angiotensin converting enzyme,ACE)在子痫前期发病机制中的作用.方法:原位杂交法检测30例子痫前期产妇(子痫前期轻度15例,重度15例)和12例正常产妇胎盘组织ACE mRNA的表达及分布;紫外分光光度法测定胎盘局部以及外周静脉血ACE活性.结果:ACE mRNA在各组产妇胎盘绒毛血管内皮细胞、滋养细胞中均可见表达.子痫前期组(3.12±0.94)明显高于对照组(1.65±0.67)(P＜0.05);子痫前期重度组和子痫前期轻度组比较,差异有统计学意义(P＜0.05).子痫前期组胎盘组织及外周静脉血ACE活性明显高于对照组(P＜0.05),子痫前期重度组和子痫前期轻度组比较,差异有统计学意义(P＜0.05).胎盘局部ACE活性与外周静脉血ACE活性呈正相关(r=0.781,P＜0.05).结论:胎盘局部ACE的表达及活性增高与子痫前期发病及病情发展密切相关.     

胎婴儿骨代谢研究进展

本文介绍了早产儿代谢性骨病发病基础及现状,主要论述了早产儿出生前后矿物质代谢特点,指出早产儿代谢性骨病发生的原因与宫内及宫外环境因素密切相关。     

从中医传统方剂初步分析中医七情之怒临床用药特点

怒在中医七情致病中有重要位置,《黄帝内经》中就认识到怒这种心理活动与生理、病理及诊疗有很大的关系,并提出了相应的治疗方法。后世医家对《内经》理论予以发挥,使怒病的脏腑治法更趋完备。     

治疗慢性肾衰单味中药（成分）研究概况

本文就近年来临床上治疗慢性肾衰（ＣＲＦ）有效的单味中药或其化学成分的研究作一综述。１大黄改善５／６肾切除ＣＲＦ大鼠的氮质血症，使血尿素氮（ＢＵＮ）、肌酐（ＳＣｒ）上升速度减慢，减少尿蛋白、增加肾小球滤过率；还能纠正脂质代谢紊乱，使ＴＧ、Ｃｈ降低，ＨＤ...     

护师参与手术室护理管理的实践

目的探讨护师参与手术室管理对护理质量的影响。方法在护士长领导下,让护师参与护理管理。结果护理质量检查中,护理管理质量指标,如无菌操作、护理文书、物品核对、急救物品完好率在实施护师参与护理管理后明显提高。结论护士长运用辅助式领导,充分利用人力资源,有效提高护师管理水平和工作责任心,提升护理质量。     

子宫平滑肌激活蛋白-1及间隙连接蛋白43在妊娠期的表达与分娩发动和早产的关系

目的　探讨激活蛋白-1(Activator protein-1,AP-1)、间隙连接蛋白43(connexin43,Cx43)在足月产和早产子宫平滑肌中的表达情况及其相关性. 方法　应用免疫组化法检测15例足月未临产、15例足月临产、10例早产临产产妇的子宫平滑肌中AP-1的两个亚单位c-Jun、c-Fos蛋白及Cx43的表达情况. 结果 (1)Cx43免疫组化积分在早产临产组(4.204±0.42)及足月临产组(4.33±0.51)表达水平显著高于足月未临产组(3.15±0.41)(P<0.01).(2)c-Jun蛋白在早产临产组、足月临产组、足月未临产组标记指数分别为(52.34±4.18)%、(45.25±5.24)%、(34.14±4.26)%,三组两两比较差异均有统计学意义(P<0.01).(3)c-Fos蛋白在早产临产组、足月临产组、足月未临产组标记指数分别为(53.48±4.36)%、(43.32±6.21)%、(31.29±3.34)%,三组两两比较差异均有统计学意义(P<0.01).(4)妊娠子宫平滑肌中Cx43表达与c-Jun、c-Fos蛋白表达呈正相关关系,(r=0.65、0.63,P<0.01). 结论 Cx43在分娩发动中发挥着重要的作用.妊娠子宫平滑肌中Cx43的表达水平与AP-1表达有一定的相关性.