快速康复外科对腹腔镜胃癌根治术患者炎症反应和免疫功能的影响

目的 探讨快速康复外科理念对腹腔镜胃癌根治术患者术后炎症反应及免疫功能的影响.方法 回顾性分析2015年5月—2016年5月该院收治的116例纳入标准的腹腔镜胃癌根治术患者资料.其中行快速康复路径的患者60例(观察组),行常规治疗56例(对照组).比较和分析两组患者术前及术后第1、4、7天C反应蛋白(C reactive protein,CRP)、降钙素原(PCT)、CD4+/CD8+.结果 两组患者CRP及PCT均较术前有所增高,对照组增高更明显(P<0.05).术后第1天观察组CRP:(17.24±10.16)mg/L,对照组CRP:(25.31±18.20)mg/L;术后第4天观察组CRP:(13.72±4.07)mg/L,对照组:(19.82±7.78)mg/L.术后第1天观察组PCT:(1.57±1.31)ng/mL,对照组PCT:(2.27±1.19)ng/mL;术后第4天观察组PCT:(1.43±1.13)ng/mL,对照组PCT:(1.85±0.96)ng/mL.CD4+/CD8+均较术前有所下降,对照组下降更明显(P<0.05).术后第4天观察组CD4+/CD8+:(1.20±0.22),对照组CD4+/CD8+:(1.10±0.16);术后第7天观察组CD4+/CD8+:(1.24±0.19),对照组CD4+/CD8+:(1.13±0.17).结论 快速康复外科理念有助于促进腹腔镜胃癌根治术患者术后的康复,减轻炎症反应,改善免疫功能.     

美沙酮药物治疗门诊吸毒人群对艾滋病的认知调查现况

目的:分析吸毒人群对艾滋病的认知现况,并作出相应评价。方法:抽取美沙酮维持治疗门诊吸毒人群为调查对象,对该人群进行问卷调查。结果:有效问卷112份,一般性知识知晓率较高(81.8%),防治知识知晓率63.11%。结论:有必要加强对该人群的健康教育,使其深入了解预防艾滋病知识,以便在预防艾滋病工作中发挥重要作用。     

1例帕金森伴异动症患者口服普拉克索致双下肢水肿的病例分析

普拉克索是一种广泛应用各期帕金森病治疗的药物,虽然疗效较好,但是近年来其所产生的不良反应时有报道。主要就1例帕金森伴异动症患者口服普拉克索导致双下肢水肿的病例进行分析。     

Clinical and pathological studies of borderline gastrointestinal stromal tumors

Background To characterize borderline gastrointestinal stromal tumors (GISTs) and identify a set of borderline criteria for practical use. Methods Medical records and specimens of 840 patients from 12 hospitals were retrospectively examined. 485 and 76 patients with any of the parameters predictive of either malignant or benign tumors were excluded. The Kaplan-Meier method was used to calculate disease-free survival and overall survival rates. Results Among the remaining 279 borderline GIST patients, 223 were followed for time periods ranging from 1 to 31.48 years. Two patients developed local recurrence, and both were cured by subsequent operations alone. The 5-year disease-free survival and overall survival rates were 99% and 100%, respectively. Morphologically, borderline GISTs typically exhibited moderate cellularity, and subsets of them also showed moderate atypia, low mitotic activities, or large tumor size. According to the NIH (National Institutes of Health) consensus criteria, the risk levels of the 279 GISTs were classified to be very low to high. However, the disease-free survival rates were not significantly different among these risk groups (P = 0.681). Conclusions The proposed borderline GIST criteria in the current study may complement the existing NIH criteria, based primarily on tumor size and mitotic count, in the evaluation of the biological behaviors of GISTs. Since a subset of borderline GISTs with high risk level showed favorable outcome, the introduction of the borderline GIST system may avoid over-diagnosis and over-therapy.     

儿童感音神经性聋139例回顾性病因分析

本文对139例感音神经性聋患儿的病因、听功能进行回顾性分析。 资料与方法 一、临床资料2000年1月-2007年10月在我科治疗的感音神经性聋患儿139例234耳,双耳病变95例190耳,单耳病变44例,其中男89例158耳,女50例76耳。年龄4～15岁,平均9．5岁。     

慢性苯中毒患者的心理分析与护理

目的分析慢性苯中毒患者的状况,研究护理方法和策略。方法对92例慢性苯中毒患者进行心理分析、临床治疗、一般护理、康复指导。结果本组92例患者经过心理分析和护理,治愈47例,有效41例,无效4例。结论慢性苯中毒一般病程较长、病情较重,优质的护理配合临床治疗能够有效帮助患者早日康复。