开塞露真空灌注工艺的改进

由于原开塞露真空灌注生产效率偏低，未能满足销售供货需要，通过对开塞露真空灌注操作中的抽真空时间、排空时间和开塞露胶球重量规格三者进行试验及改进，最终达到提高灌注生产效率的目的。     

人工晶体植入术731只眼临床分析

人工晶体植入术７３１只眼临床分析洪荣照，吴国基，谭怡，唐舒静，苏淑娟１９８９～１９９１年我院共行人工晶体植入术５９９例（７３１只眼），占同期白内障手术的９５．４％，现报告如下：一、材料和方法１．一般资料：本组采用美国产人工晶体５４２只眼，国产者为１８...     

独眼玻璃体视网膜疾病患者的临床特征及手术治疗效果

目的: 探讨独眼(对侧眼为盲)患者玻璃体视网膜疾病的临床特征及手术治疗效果。方法: 回顾性连续病例研究。分析2006-01/2010-02本中心眼底病专科确诊的68例独眼患者的临床资料,分析该特殊群体的临床特点,对手术方案、眼内填充物的选择、手术前后视力、术中术后并发症、解剖成功率及预后进行重点分析。术后随访4mo～5a,平均11.30±9.57mo,以最后一次随访作为疗效判断时间点。结果: 术后视力明显提高,68例患者中,0.05以上者从术前的22眼(32.4%)提高到术后的60眼(88.2%),0.3以上者从术前的3眼(4.4%)提高到术后的37眼(54.4%)。手术前后最佳矫正视力(BCVA)差异具有统计学意义(t=8.986,P<0.01)。结论: 玻璃体视网膜手术可以使大部分独眼患者避免因玻璃体视网膜疾病导致的盲和低视力。     

曲安奈德辅助玻璃体后脱离联合不染色剥除内界膜治疗Ⅱ、Ⅲ期特发性黄斑裂孔的临床观察

目的 评价曲安奈德(TA)辅助玻璃体后脱离(PVD)联合不染色剥除内界膜(ILM)治疗Ⅱ、Ⅲ期特发性黄斑裂孔(IMH)的解剖和视力预后.方法 对Ⅱ、Ⅲ期IMH患者23例23只眼常规行最佳矫正视力(BCVA)、晶状体状态、光相干断层扫描(OCT)检查并进行黄斑裂孔分期.手术前BCVA为0.04～0.40,最小视角对数(logMAR)视力为0.398～1.398,平均0.846±0.310.患者均先在TA辅助下行人工PVD,然后在无染色条件下剥除黄斑区ILM.手术中联合白内障摘除手术5只眼.手术后随访时间6～16个月,平均随访时间9个月.统计分析黄斑裂孔解剖成功率、手术前后BCVA、手术并发症.结果 手术后1个月OCT检查显示,黄斑裂孔闭合22只眼,占95.7%;黄斑裂孔未闭合1只眼,占4.3%,再行气液交换后黄斑裂孔成功闭合.至随访期末,均未见黄斑裂孔重新开放.手术后6个月BCVA为0.12～0.90,logMAR视力为0.046～0.921,平均视力为0.410±0.209,手术前后BCVA比较,差异有统计学意义(t=6.636,P＜0.000 1).视力提高21只眼,占91.3%;视力不变者2只眼,占8.7%;无视力下降者.剥除ILM 时视网膜表面出现1～3个点状自限性出血者5只眼.手术后未发生视网膜脱离或玻璃体积血等严重并发症.手术后晶状体核密度增加9只眼,一过性眼压升高6只眼.结论 TA辅助PVD联合不染色剥除ILM治疗Ⅱ、Ⅲ期IMH是一种安全有效的方法.

Abstract：

Objective To evaluate the anatomic and visual outcomes of idiopathic macular holes treated with triamcinolone (TA)-assisted posterior vitreous detachment (PVD) and then internal limiting membrane (ILM) peeling without any dye. Methods Twenty-three patients (23 eyes) with stage Ⅱand Ⅲidiopathic macular holes were enrolled. The best-corrected visual acuity (BCVA), the lens, the duration,stage and size of the macular holes were measured before and after the surgery. The preoperative BCVA was 0.04 to 0.40; the logMAR was 0.398 to 1.398 with the mean of 0.846±0.310. All surgery involved TA-assisted PVD and then ILM peeling without any dye.Combined cataract extraction with vitrectomy was performed on 5 eyes.The follow-up ranged from 6 to 16 months with the mean of 9 months. Results Anatomic macular hole closure was achieved in 22 eyes (95.7%) at the first month after surgery and in 23eyes (100.0%) finally. At the 6th months after surgery, the BCVA was 0.12 to 0.90, logMAR was 0.046 to 0.921 with the mean of 0.410±0.209, compared with preoperative BCVA, the difference was statistically significant (t=6.636, P＜0.0001). BCVA increased in 21 eyes (91.3%) and kept unchanged in 2 eyes (8.7%). There are 1-3 spots self-limited bleeding on the retinal surface when the ILM was peeled in 5 eyes. Postoperative complications included progression of cataract in 9 patients and transient intraocular pressure elevation in 6 patients. Conclusions TA-assisted PVD and then ILM peeling without any dye is an effective and safe surgical technique in stage Ⅱ and Ⅲ idiopathic macular hole.