加强护理教学中的审美教育

现代医学护理教育的目的，是造就一大批以维护人体健康和人体美为己任的专业护理人才。医学模式的转变和护理事业的发展，要求护理人才不仅应该具有扎实的理论基础、熟练的操作技能和高尚的道德情操，而且应该掌握护理美学的基本知识。护理美学的临床应用价值决定了它在护理教育中的重要地位。     

肺宝冲剂治疗哮喘的临床观察

一年来,我科应用肺宝冲剂治疗哮喘27例,并与公认有效药物进行对照观察,效果满意,报告如下。一、一般情况病例选择:本组27例均按全国统一诊断标准明确诊断。27例中支气管哮喘19例,慢性支气管炎阻塞性肺气肿8例。男患15例,女患12例。年令50岁以上15例,20～50岁     

小儿肺炎支原体感染158 例临床分析

目的:探讨儿童肺炎支原体(MP)感染的临床特点和诊治方法.方法:对2008年1月-2009年6月被确诊为MP感染的158 例住院患儿进行回顾分析,并对红霉素和阿奇霉素两种治疗方法进行对比.结果:阿奇霉素及红霉素两种治疗方法的治疗效果差异无统计学意义,阿奇霉素组的总有效率为91.7%大于红霉素组的89.8%.结论:MP感染的发病率较高,以学龄前儿童为主.不同年龄组临床表现各异,阿奇霉素可作为治疗的首选药物.     

全髋关节置换术后预防假体脱位的护理进展

全髋关节置换术（THA）是利用人工材料将人体的股骨头和髋臼置换以重建关节运动功能的一种修复手段。被称为本世纪的一个重大贡献,其手术目的是减轻或解除患者髋关节的疼痛,改善关节功能,提高患者生活质量。但术后易发生各种局部和全身并发症,假体脱位是全髋关节置换术后常见而严重的并发症之一,其发生率为0．2％-6．2％。全髋关节置换术后假体脱位会给患者带来极大的痛苦,给患者家庭带来较重的经济负担,     

原发性肝癌的发生机制及中西医治疗研究进展

<正>原发性肝癌是我国乃至世界上最常见、最具有危害性的恶性肿瘤之一。世界卫生组织国际癌症研究署发布的2015年全球癌症报告显示,全球肝癌死亡人数约为75.1万,我国每年约有38.3万人死于肝癌,占全球肝癌死亡总数的51%~([1])。近年来肝癌发病率和死亡率呈上升趋势,严重威胁人类生命健康~([2])。目前,肝癌的5年生存率大约为14%~([3]);由于起病隐匿,肝癌被发现时多处于中晚期,并且大部分常合并肝硬化,同时伴有肝功能异常,此时手术治疗或化学栓塞     

预防性光疗对早产儿黄疸防治的临床观察

目的：探讨预防性光疗对早产儿黄疸的影响。方法：对64例生后24h内入院的早产儿使用经皮黄疸仪早期监测黄疸,如果黄疸指数大于6mg／dL（102μmol／L）,或每日黄疸指数增加3mg／dL（51μmol／L）,即予单面蓝光灯照射8h-12h,停16h-12h,直至黄痘消退。结果：所有患儿经皮黄疸仪所测黄疸指数均小于10mg／dL（17lμmol／L）,经抽血检验总胆红素峰值均小于171μmol／L,无1例出现胆红素脑病。结论：对早产儿黄疸进行预防性光疗,既可预防早产儿高胆红素血症的发生又可避免胆红素脑病的发生。     

肾康胶囊的临床应用

我们与哈医大一院合作从1997年开始应用肾康胶囊治疗急性肾小球肾炎,慢性肾小球肾炎,慢性肾盂肾炎,单纯性前列腺炎(前列腺炎)这几种疾病271例进行观察,现将结果报告如下。1一般资料     

中药对慢性肾衰竭的保护及延缓作用

目的研究保肾康合剂对庆大霉素所致的急性肾损伤大鼠肾功能的保护作用.方法取大鼠40只,其中10只作为正常对照组,其余30只制成急性肾损伤模型,并随机分为三组保肾康组用保肾康溶液灌胃;包醛组用包醛氧淀粉灌胃;病模组(同正常组)用0.85%生理盐水灌胃.治疗10天,观察各组血肌酐(Scr)、尿素氮(BuN)和尿酶(NAG)的变化;将大鼠处死后观察其肾组织的病理改变.结果保肾康组治疗后(Scr)、(BuN)和(NAG)较病模组明显下降,并优于包醛组(P＜0.01);光镜检查保肾康合剂可使肾小管上皮细胞肿胀,坏死等组织病理改变明显减轻,电镜下可见线粒体损伤等变化亦显著减轻.结论保肾康合剂可改善急性肾损伤大鼠的肾功能,减轻水肿,阻止庆大霉素对肾小管上皮细胞的进一步损害.     

Effect of Dexamethasone and Aquaporin-1 Antisense Oligonucleotides on the Aquaporin-1 Expression in Cultured Human Trabecular Meshwork Cells

The changes in the expression of aquaporin-1 （AQP1） mRNA and protein in cultured human trabecular meshwork （HTM） cells treated with dexamethasone and transfected with antisense oligonucleotides （AS-ODN） were studied, and the implication of AQP1 regulation in corticosteroid-glaucoma and the possibility of AS-ODN inhibiting the AQP1 expression were evaluated. The cultured HTM cells in vitro were treated with different concentrations of dexamethasone and transfected with oligonucleotides for 5 days respectively. Then, total RNA and protein of HTM cells were extracted. The changes of AQP1 mRNA and protein were demonstrated qualitatively and quantitatively by RT-PCR and Western blot. Band intensities were detected by imaging analysis. There was a parallel relationship between the results of RT-PCR and those of Western blot. The expression levels of AQP1 mRNA and protein in dexamethasone-treated groups were increased initially and decreased later as dexamethasone concentration was stepped up. In the 0.04 μg/mL and 0.4 μg/mL groups, the levels of AQP1 were higher than in control group （0 μg/mL）. In the 4 μg/ mL and 40 μg/mL groups, the AQP1 expression levels were lower than in control group. AS-ODN could down-regulate the expression of AQP1 mRNA and protein in a dose-dependent manner. At 5 μg/mL, down-regulation efficiency reached the maximum. There was no statistically significant difference in the expression of AQP1 mRNA and protein between all sense oligonucleotides groups and control group. It was suggested that dexamethasone may induce the changes of the AQP1 expression in HTM cells to be involved in the occurrence of corticosteroid-glaucoma. AS-ODN can down-regulate the AQP1 expression in HTM cells to some extent.