The correlation between TNF-α, IL-6 in cervical mucous during follicular development and ovulation stimulation in different protocols

Objective To investigate the correlation between TNF-α and IL-6 levels in cervical mucous during follicular development and ovulation stimulation in different protocols.Methods 36 infertile women were set up as experimental groups,divided into CC, HMG, IVF-ET group,each group consisted of 12 infertile women and 15 women with normal menstrual cycles were choiced as control group.Cervical mucous during follicular phase, luteal phase and ovulation phase were collected.TNF-α, IL-6 levels in cervical mucous were measured by radioimmunology assay (RIA).Follicular development were monitored by transvaginal ultrasonagraphy.Results (1) TNF-α levels in cervical mucous of experimental groups and control group were periodically various among the reproductive cycle.It increased during follicular phase, reached to peak during ovulation phase, and decreased during luteal phase (P＜0.05).IL-6 levels had no obvious periodical changes.(2) Compared with CC and control group, levels of TNF-α,IL-6 in HMG and IVF-ET group were significantly higher (P＜0.05).(3) Levels of TNF-α and IL-6 in cervical mucous were positively correlated with the dominant follicle diameter (r=0.261, r=0.192 respectively,P＜0.05).(4) TNF-α and IL-6 showed positive correlation in the reproductive cycle (r=0.782,P＜0.05).Conclusions (1) TNF-α level shows a cyclic change in the reproductive cycle and peaks during ovulation,whereas IL-6 level does not.(2) TNF-α and IL-6 may play a certain role in the process of follicular development and ovulation.(3)The levels of TNF-α and IL-6 are up-regulated by gonadotrophic hormone.(4) TNF-α and IL-6 may have coordination properties and participate in the same biological effects.     

果糖二磷酸钠并发急性高磷血症危象2例

急性高磷血症危象是一种严重危及生命的电解质紊乱，可以引起一系列相关的临床表现，国内外资料较少．我科近期收治了2例患者均在应用果糖二磷酸钠后出现急性高磷血症危象，报道如下。     

豚鼠前庭感觉细胞中同时检测一氧化氮和活性氧基

近来有相当多的证据提示一氧化氮(NO)和与其有关的活性氧基(ROS)在某些内耳疾病中起到关键作用,例如听觉器官外伤、迷路炎、氨基糖苷类抗生素与顺铂的耳中毒以及内淋巴积水。很多关于ROS在氨基     

月经紊乱与减肥

如今，不仅芳龄少女对健美顶礼膜拜，甚至中老年女士也不甘寂寞，纷纷跃跃欲试。减肥药、减肥食品、减肥茶、苗条霜应运而生，广告铺天盖地，迎面扑来。有相当多的人将身材苗条婀娜，认作女性美的标志，刻意追求瘦的体形。     

健康公告

厨房噪音stop 各种调味瓶、碗碟、炊具碰撞时发出的叮[口当]声、抽油烟机在运转时发出的呼呼声、橱柜柜门闭合时发出的噼啪声……厨房里这些恼人的声音都会增添你下厨时的焦躁情绪。医学证实，过度的噪音污染，会导致人的耳部不适，出现耳鸣耳痛症状；损害心血管；     

人文关怀在膀胱粘膜-尿道一期成形术后的应用

目的 研究人文关怀在膀胱黏膜-尿道一期成形术后的作用.方法 将49例尿道下裂患者按单、双住院号分设为研究组(实施人文关怀)和对照组(常规护理),统计两组患者的情绪状态和手术并发症的发生率,进行统计学处理.结果两组患者的情绪状态经u检验P＜0.05,并发症发生率经x2检验P＜0.05,有显著性差异.结论人文关怀确实在膀胱黏膜-尿道一期成形术后护理中起到了极为重要的作用.     

春意迷人,吊带背心艳光四射

潮流感十足的吊带背心与时尚界流行的蓬蓬袖、荷叶边、高腰结、花卉图案等年轻的时尚风格开始逐渐融合。到底哪一款最讨你喜欢,快看看就知道啦……     

冉冉升起的“东方明珠”——访山东省妇产医院院长孙洪军

在济南东部人文社区冉冉升起一颗璀璨的明珠,引起泉城人的关注。她就是山东省妇产医院(山东省立医院妇产医院)。她是山东省第一家集临床和保健为一体的省级现代化妇产医院,为济南市城镇职工生育保险定点医疗单位。医院南靠浆水泉风景区。北望经十东路景观大道,院内绿树红瓦交相     

HP-1351胎儿监护仪临床应用

HP-1315胎儿监护仪对母婴无痛苦无损伤，医务人员能通过超声探头从外部来动态监护胎儿的心率，用ToCo传感器监护子宫活动，了解子宫收缩的频率和持续时间及宫缩时对胎心率的影响，并能了解胎儿运动时胎心率的变化情况。胎心率的变化是胎儿中枢神经系统正常调节机能的表现，胎儿中枢神经系统最缺乏对低氧的耐受性，而且它一次受损会留下终身后遗症。     

新时期下疾病预防控制中的行政管理

疾病预防控制中心作为国家公共卫生领域公益事业类单位的重要成员，在疾病预防控制系统中处于重要位置。在当今构建“以人为本”的和谐社会和落实科学发展观的政策环境下，加之医学模式的转变和疾病谱的变化，在广大群众对健康质量的要求越来越高的情况下，疾控中心承担的社会功能需要进一步完善，职责需要更加明确，任务也更加繁重。而努力提高兰州市疾控中心的行政效能，完善其功能保障可以有效缓解其所面临的种种压力，因此探讨新时期下疾控中心的行政管理便成为题中之议。