全文获取类型
| 收费全文 | 252214篇 |
| 免费 | 14158篇 |
| 国内免费 | 1682篇 |
专业分类
| 耳鼻咽喉 | 3750篇 |
| 儿科学 | 7581篇 |
| 妇产科学 | 7235篇 |
| 基础医学 | 38334篇 |
| 口腔科学 | 7915篇 |
| 临床医学 | 20428篇 |
| 内科学 | 46037篇 |
| 皮肤病学 | 6304篇 |
| 神经病学 | 21803篇 |
| 特种医学 | 9766篇 |
| 外国民族医学 | 3篇 |
| 外科学 | 37127篇 |
| 综合类 | 5827篇 |
| 一般理论 | 73篇 |
| 预防医学 | 16018篇 |
| 眼科学 | 5820篇 |
| 药学 | 19331篇 |
| 中国医学 | 1011篇 |
| 肿瘤学 | 13691篇 |
出版年
| 2021年 | 2177篇 |
| 2020年 | 1711篇 |
| 2019年 | 2420篇 |
| 2018年 | 4484篇 |
| 2017年 | 3641篇 |
| 2016年 | 4392篇 |
| 2015年 | 4187篇 |
| 2014年 | 4910篇 |
| 2013年 | 7810篇 |
| 2012年 | 10389篇 |
| 2011年 | 11545篇 |
| 2010年 | 6665篇 |
| 2009年 | 4966篇 |
| 2008年 | 11274篇 |
| 2007年 | 11896篇 |
| 2006年 | 11601篇 |
| 2005年 | 11075篇 |
| 2004年 | 10406篇 |
| 2003年 | 10278篇 |
| 2002年 | 10019篇 |
| 2001年 | 11803篇 |
| 2000年 | 13413篇 |
| 1999年 | 9275篇 |
| 1998年 | 3266篇 |
| 1997年 | 2559篇 |
| 1996年 | 1849篇 |
| 1995年 | 1631篇 |
| 1994年 | 1538篇 |
| 1993年 | 1489篇 |
| 1992年 | 4420篇 |
| 1991年 | 4369篇 |
| 1990年 | 4100篇 |
| 1989年 | 4122篇 |
| 1988年 | 3904篇 |
| 1987年 | 3832篇 |
| 1986年 | 3547篇 |
| 1985年 | 3641篇 |
| 1984年 | 2690篇 |
| 1983年 | 2344篇 |
| 1982年 | 1558篇 |
| 1981年 | 1374篇 |
| 1979年 | 2378篇 |
| 1978年 | 1618篇 |
| 1977年 | 1449篇 |
| 1975年 | 1585篇 |
| 1974年 | 1736篇 |
| 1973年 | 1736篇 |
| 1972年 | 1616篇 |
| 1971年 | 1532篇 |
| 1970年 | 1390篇 |
排序方式： 共有10000条查询结果，搜索用时 15 毫秒
61.
62.
Background Context
Long-term follow-up of patient-reported outcome measures (PROM) is essential in both modern spinal care and research. Lack of time and staff are commonly reported barriers to implementing long-term follow-up of PROM. Automated and digital follow-up systems for PROM collection are seeing widespread use, yet their validity and comparative effectiveness have never been evaluated.Purpose
The present study aimed to assess the validity of digital follow-up systems in comparison with the conventional paper-based follow-up (PB-FU).Study Design
This is a retrospective analysis of prospectively collected double follow-up data.Patient Sample
Patients who underwent lumbar spinal fusion for spondylolisthesis or degenerative disc disease between 2013 and 2016 were included in the study.Outcome Measures
The study determined the Oswestry Disability Index (ODI) and Numeric Rating Scale (NRS) for back and leg pain severity at baseline, 6 weeks, 12 months, and 24 months.Materials and Methods
After lumbar spinal fusion surgery, a double follow-up of PROM was carried out by conventional PB-FU during clinical visits, while simultaneously completing an automatically dispatched digital follow-up questionnaire. As the primary end point, we assessed the intraindividual discrepancy in PROM between PB-FU and automated digital follow-up (AD-FU).Results
Forty patients completed all parts of the dual follow-up trajectory and were analyzed. We detected no discrepancy in ODI or NRS for back and leg pain severity at any of the baseline, 6-week, 12-month, or 24 month follow-ups (all p>.05). This was confirmed in a sensitivity analysis.Conclusions
In an analysis of dual paper-based and digital follow-up after lumbar fusion surgery, patients report highly similar values using either method of follow-up. It appears that AD-FU without incentives produces lower response rates. To reassess the validity of these systems for data collection in spinal patient care, a prospective validation with higher statistical power is warranted. 相似文献63.
Jeroen M. van de Pol Jurjen G. Geljon Svetlana V. Belitser Geert W.J. Frederix Anke M. Hövels Marcel L. Bouvy 《Research in social & administrative pharmacy》2019,15(1):70-76
Introduction
The nature of community pharmacy is changing, shifting from the preparation and distribution of medicines to the provision of cognitive pharmaceutical services (CPS); however, often the provision of traditional services leaves little time for innovative services. This study investigated the time community pharmacists spend on the tasks and activities of daily practice and to what extent they are able to implement CPS-related services in daily practice.Methods
Self-reporting work sampling was used to register the activities of community pharmacists. A smartphone application, designed specifically for this purpose, alerted participants to register their current activity five times per working day for 6 weeks. Participants also completed an online survey about baseline characteristics.Results
Ninety-one Dutch community pharmacists provided work-sampling data (7848 registered activities). Overall, 51.5% of their time was spent on professional activities, 35.4% on semi-professional activities, and 13.1% on non-professional activities. The proportion of time devoted to CPS decreased during the workweek, whereas the time spent on traditional task increased.Discussion and conclusion
This study shows it is feasible to collect work-sampling data using smartphone technology. Community pharmacists spent almost half of their time on semi-professional and non-professional activities, activities that could be delegated to other staff members. In practice, the transition to CPS is hampered by competing traditional tasks, which prevents community pharmacists from profiling themselves as pharmaceutical experts in daily practice. 相似文献64.
65.
66.
67.
Primary syphilis in HIV‐negative patients is on the rise in Greece: epidemiological data for the period 2005–2012 from a tertiary referral centre in Athens,Greece 
下载免费PDF全文
下载免费PDF全文 68.
Leonardo Jönck Staub Roberta Rodolfo Mazzali Biscaro Erikson Kaszubowski Rosemeri Maurici 《The Journal of emergency medicine》2019,56(1):53-69
Background
Lung ultrasound can accelerate the diagnosis of life-threatening diseases in adults with respiratory symptoms.Objective
Systematically review the accuracy of lung ultrasonography (LUS) for emergency diagnosis of pneumonia, acute heart failure, and exacerbation of chronic obstructive pulmonary disease (COPD)/asthma in adults.Methods
PubMed, Embase, Scopus, Web of Science, and LILACS (Literatura Latino Americana e do Caribe em Ciências da Saúde; until 2016) were searched for prospective diagnostic accuracy studies. Rutter-Gatsonis hierarchical summary receiver operating characteristic method was used to measure the overall accuracy of LUS and Reitsma bivariate model to measure the accuracy of the different sonographic signs. This review was previously registered in PROSPERO (Centre for Reviews and Dissemination, University of York, York, UK; CRD42016048085).Results
Twenty-five studies were included: 14 assessing pneumonia, 14 assessing acute heart failure, and four assessing exacerbations of COPD/asthma. The area under the summary receiver operating characteristic curve of LUS was 0.948 for pneumonia, 0.914 for acute heart failure, and 0.906 for exacerbations of COPD/asthma. In patients suspected to have pneumonia, consolidation had sensitivity of 0.82 (95% confidence interval [CI] 0.74–0.88) and specificity of 0.94 (95% CI 0.85–0.98) for this disease. In acutely dyspneic patients, modified diffuse interstitial syndrome had sensitivity of 0.90 (95% CI 0.87–0.93) and specificity of 0.93 (95% CI 0.91–0.95) for acute heart failure, whereas B-profile had sensitivity of 0.93 (95% CI 0.72–0.98) and specificity of 0.92 (95% CI 0.79–0.97) for this disease in patients with respiratory failure. In patients with acute dyspnea or respiratory failure, the A-profile without PLAPS (posterior-lateral alveolar pleural syndrome) had sensitivity of 0.78 (95% CI 0.67–0.86) and specificity of 0.94 (95% CI 0.89–0.97) for exacerbations of COPD/asthma.Conclusion
Lung ultrasound is an accurate tool for the emergency diagnosis of pneumonia, acute heart failure, and exacerbations of COPD/asthma. 相似文献69.
Amy Y. Zhang Christopher Burant Alex Z. Fu Gerald Strauss Donald R. Bodner Lee Ponsky 《Journal of psychosocial oncology》2020,38(2):210-227
AbstractPurpose: We examined underlying psychosocial processes of a behavioral treatment for urinary incontinence (UI) of prostate cancer survivors.Design: Secondary analysis of data collected from a clinical trial.Sample: Two hundred forty-four prostate cancer survivors who participated in a clinical trial of behavioral intervention to UI as intervention or control subjects.Methods: The participants had a 3-month behavioral intervention or usual care and were followed up for an additional 3?months. They were assessed at baseline, 3, and 6?months. Latent growth curve models were performed to examine trajectories of each study variable and relationships among the variables.Findings: Increasing self-efficacy and social support were significantly and independently associated with more reduction of urinary leakage frequency over time.Implications for psychosocial oncology: Providing problem-solving skills and social support, including peer support, are essential for empowering patients to reduce UI. 相似文献
70.