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51.
Omran Tarek A. Garoushi Sufyan Abdulmajeed Aous A. Lassila Lippo V. Vallittu Pekka K. 《Clinical oral investigations》2017,21(5):1717-1724
Clinical Oral Investigations - Bulk-fill resin composites (BFCs) are gaining popularity in restorative dentistry due to the reduced chair time and ease of application. This study aimed to evaluate... 相似文献
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Pekka Ahlholm Kirsi Sipilä DDS PhD Pekka Vallittu DDS PhD CDT Minna Jakonen DDS PhD Ulla Kotiranta DDS 《Journal of prosthodontics》2018,27(1):35-41
Purpose
To conduct a systematic review to evaluate the evidence of possible benefits and accuracy of digital impression techniques vs. conventional impression techniques.Materials and Methods
Reports of digital impression techniques versus conventional impression techniques were systematically searched for in the following databases: Cochrane Central Register of Controlled Trials, PubMed, and Web of Science. A combination of controlled vocabulary, free‐text words, and well‐defined inclusion and exclusion criteria guided the search.Results
Digital impression accuracy is at the same level as conventional impression methods in fabrication of crowns and short fixed dental prostheses (FDPs). For fabrication of implant‐supported crowns and FDPs, digital impression accuracy is clinically acceptable. In full‐arch impressions, conventional impression methods resulted in better accuracy compared to digital impressions.Conclusions
Digital impression techniques are a clinically acceptable alternative to conventional impression methods in fabrication of crowns and short FDPs. For fabrication of implant‐supported crowns and FDPs, digital impression systems also result in clinically acceptable fit. Digital impression techniques are faster and can shorten the operation time. Based on this study, the conventional impression technique is still recommended for full‐arch impressions. 相似文献55.
Hautamäki MP Aho AJ Alander P Rekola J Gunn J Strandberg N Vallittu PK 《Acta orthopaedica》2008,79(4):555-564
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Objectives – Myxovirus resistance protein A (MxA) can be used as a marker of the bioactivity of interferon-beta (IFN-β) therapy. Two to forty per cent of IFN-β-treated multiple sclerosis (MS) patients develop IFN-β-neutralizing antibodies (NAb) with subsequent attenuation of MxA protein induction. The aim of this study was to set up a simple MxA enzyme immunoassay (EIA) for the measurement of MxA protein and to evaluate the EIA test by comparing the results with flow cytometric analysis and the measurement of NAb.
Methods – total of 51 IFN-β-treated relapsing–remitting MS (RRMS) patients were tested for MxA protein expression by using both MxA EIA assay and flow cytometric analysis. Thirteen patients were confirmed to be NAb-positive.
Results – The correlation between EIA and flow cytometric analysis was significant with a wider range of measured levels in the EIA. Patients with NAb had low MxA levels, but in some patients, remaining MxA induction could be detected despite NAb.
Conclusions – The MxA EIA assay seems to be a practical method for large-scale analysis of the bioactivity of IFN-β treatment. 相似文献
Methods – total of 51 IFN-β-treated relapsing–remitting MS (RRMS) patients were tested for MxA protein expression by using both MxA EIA assay and flow cytometric analysis. Thirteen patients were confirmed to be NAb-positive.
Results – The correlation between EIA and flow cytometric analysis was significant with a wider range of measured levels in the EIA. Patients with NAb had low MxA levels, but in some patients, remaining MxA induction could be detected despite NAb.
Conclusions – The MxA EIA assay seems to be a practical method for large-scale analysis of the bioactivity of IFN-β treatment. 相似文献
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OBJECTIVES: Longevity of particulate filler resin (PFR) is controversial for large restorations with high occlusal-stresses. The aim of this study was to reinforce PFR with fiber reinforced composite (FRC) and to evaluate the effect of thickness of FRC substructure and thickness of overlaying PFR, on the static load-bearing capacity of the material combination. METHODS: A total of 336 test specimens having a FRC substructure (short random or continuous bidirectional fibre orientation) and layer of restorative PFR were prepared for this study. In Group A, the specimens contained short random oriented fibres (length: 2-3mm) and in Group B, there were continuous bidirectionally oriented fibres. The specimens (n = 12/group) were polymerized with a hand light-curing unit and were either dry-stored or thermocycled before they were statically loaded with a steel ball until fracture, using a universal testing machine. RESULTS: Increase the volume fraction of the short random FRC versus the fraction of PFR, the load-bearing capacity of the specimen increased (p < 0.001). Short random FRC revealed significantly different behavior than the bidirectionally oriented FRC (p < 0.001). By combining the FRC layer of 0.5mm in thickness with a layer of 2.5mm of PFR gave load values of 1462N and 1196N, which were considerably higher than values for plain PFR of 3mm in thickness (782N and 729N). CONCLUSION: The results suggest that by adding a FRC substructure under the PFR, the load-bearing capacity of the material combination was increased. 相似文献
58.
Garoushi SK Lassila LV Tezvergil A Vallittu PK 《The journal of contemporary dental practice》2006,7(4):1-8
AIM: The aim of this study was to determine the static load-bearing capacity of composite resin onlay restorations made of particulate filler composite (PFC) with two different types of fiber-reinforced composite (FRC) substructures. In addition, flexural properties of the material combination and the effect of polymerization devices were tested. METHODS AND MATERIALS: Specimens were prepared to simulate an onlay restoration, which consisted of 2 to 3 mm of FRC layer as a substructure (short random and continuous bidirectional fiber orientation) and a 1 mm surface layer of PFC. Control specimens were prepared from plain PFC. In Group A the specimens were incrementally polymerized only with a hand-light curing unit for 40 s, while in Group B the specimens were post-cured in a light-curing oven for 15 min before they were statically loaded with a steel ball. Bar-shaped test specimens were prepared to measure the flexural properties of material combination using a three-point bending test (ISO 10477). RESULTS: Analysis of variance (ANOVA) revealed all specimens with a FRC substructure have higher values of static load-bearing capacity and flexural properties than those obtained with plain PFC (p<0.001). CONCLUSION: The load-bearing capacity of all the specimens decreased after post-curing and water storage. Restorations made from a material combination of FRC and PFC showed better mechanical properties than those obtained with plain PFC. 相似文献
59.
Bouillaguet S Schütt A Alander P Schwaller P Buerki G Michler J Cattani-Lorente M Vallittu PK Krejci I 《Journal of biomedical materials research. Part B, Applied biomaterials》2006,76(1):98-105
Fiber-reinforced composites (FRCs) show great promise as long-term restorative materials in dentistry and medicine. Recent evidence indicates that these materials degrade in vivo, but the mechanisms are unclear. The objective of this study was to investigate mechanisms of deterioration of glass fiber-polymer matrix bond strengths in dental fiber-reinforced composites during hydrothermal and mechanical aging. Conventional three-point bending tests on dental FRCs were used to assess flexural strengths and moduli. Micro push-out tests were used to measure glass fiber-polymer matrix bond strengths, and nanoindentation tests were used to determine the modulus of elasticity of fiber and polymer matrix phases separately. Bar-shaped specimens of FRCs (EverStick, StickTech, and Vectris Pontic, Ivoclar-Vivadent) were either stored at room temperature, in water (37 and 100 degrees C) or subjected to ageing (10(6) cycles, load: 49 N), then tested by three-point bending. Thin slices were prepared for micro push-out and nanoindentation tests. The ultimate flexural strengths of both FRCs were significantly reduced after aging (p < 0.05). Both water storage and mechanical loading reduced the interfacial bond strengths of glass fibers to polymer matrices. Nanoindentation tests revealed a slight reduction in the elastic modulus of the EverStick and Vectris Pontic polymer matrix after water storage. Mechanical properties of FRC materials degrade primarily by a loss of interfacial bond strength between the glass and resin phases. This degradation is detectable by micro push-out and nanoindentation methods. 相似文献
60.
Ritva M. Lindblad Lippo V.J. Lassila Veijo Salo Pekka K. Vallittu Leo Tjäderhane 《Journal of dentistry》2010