复尔康胶囊抗肿瘤作用的研究

目的:研究复尔康胶囊对小鼠移植肿瘤的抑制作用和对多种肿瘤化疗药物的增效作用。方法:测定高、中、低剂量复尔康胶囊(500、250、125mg.kg-1)对小鼠移植肿瘤S180、H22、Lewis的抑瘤率;并将复尔康胶囊与不同作用机制的肿瘤化疗药物(丝裂霉素、氟尿嘧啶、顺铂、平阳霉素、羟喜树碱、阿霉素)合用,测定其对小鼠移植肿瘤S180、H22、Lewis的抑瘤率。结果:复尔康胶囊对3种小鼠移植肿瘤均有显著抑制作用(P<0.01),与肿瘤化疗药物合用对小鼠移植肿瘤S180、H22、Lewis的抑瘤率比单用肿瘤化疗药物效果更好(P<0.05)。结论:复尔康胶囊不但具有明显的抗肿瘤作用,而且对不同作用机制的肿瘤化疗药物具有显著的增效作用。     

Laparoscopic liver resection for benign and malignant liver tumors

BACKGROUND:Laparoscopic liver resection is one of the most complex procedures in hepatobiliary surgery.In the last two decades,laparoscopic liver surgery has emerged as an option at major academic institutions.The purpose of this study is to describe the initial experience of minimally invasive liver resections at a non-academic institution. METHODS:We retrospectively reviewed medical records of patients undergoing laparoscopic liver resections between June 2006 and December 2009 at our center.Indications, ...     

精神医学科研方法(3):中国精神卫生研究中工具和量表的使用(英文)

Almost all mental health research involves the use of instruments or scales.These are employed to make diagnoses;to measure the severity of symptoms;to assess knowledge,attitudes and behaviors;and for a wide range of other purposes.Much of the reported mental health research in China employs Chinese versions of scales from the     

Small-duct primary sclerosing cholangitis with hepatocellular carcinoma requiring liver transplantation

BACKGROUND:Primary sclerosing cholangitis(PSC)is a chronic progressive cholestatic liver disease,which usually affects young adults and is diagnosed by cholangiography.On a few occasions,the disease either starts in or exclusively involves the small intrahepatic bile ducts,referred to as small-duct PSC. METHODS:A 31-year-old man presented with severe hematemesis secondary to liver cirrhosis.Over a course of 8 years,his liver decompensated and required an orthotopic liver transplantation. In this report we d...     

乙型肝炎病毒polyA形成与调节因素研究进展

乙型病毒性肝炎(乙肝)是全球范围的重大公共卫生问题之一,其病原体乙型肝炎病毒(HBV)可通过多种途径感染人体,引起急性肝炎、慢性肝炎、肝硬化甚至肝癌。HBV感染是全球十大死因之一,世界上30%的人感染过或者成为HBV的携带者。据统计[1],全球共有3.5亿HBV慢性感染者,每年因HBV慢性感染所致的肝纤维化或者肝癌感染致死的人数有100万左右。     

性纯洁和“安全性行为”——两种性教育的比较（一）

禁欲(童贞、性纯洁)教育和“安全性行为”教育比较说到性教育,几乎没有人会无动于衷,事实上,每个人对学校是否应该对学生进行性教育,应该教些有关性的什么知识和应该怎样教,都有自己的看法。总的来说,这个问题一般归结为两种意见。意见1:性教育课程应主要教育学生使用避孕套和其他避孕方法,使他们在进行性行为时,健康受到最低程度的伤害。(“安全性行为”方式) 意见2:性教育课程应主要促进学生保持童贞,直到他们找到准备与之生活一辈子的人,结婚后再发