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91.
Aoki T Noma N Takajo I Yamaga J Otsuka M Yuchi H Ishikawa N Inatsu H Sakata J Asada Y Eto T 《Journal of gastroenterology》2002,37(3):204-209
99m Tc-labeled human serum albumin scintigram showing abnormal radioactivity in the stomach. Endoscopic gastric biopsies revealed
nonspecific inflammation, but marked intramural edema. Based on a slight elevation of antinuclear antibody level, autoimmune
disease was suspected to be involved in this patient. Administration of prednisolone, as a diagnostic therapy, alleviated
the hypoproteinemia, hypoalbuminemia, and hypercholesteremia. These findings suggest that an autoimmune mechanism could have
been involved in this case of protein-losing gastropathy.
Received: September 4, 2000 / Accepted: February 23, 2001 相似文献
92.
Igawa T Nagafuji K Ejima J Nakasuga K Ito H Kaji Y Miyamoto T Harada M 《Internal medicine (Tokyo, Japan)》2003,42(4):336-339
A 74-year-old man was referred to us for evaluation of a tumor in the right atrium (RA). Transesophageal echocardiography (TEE) showed an unmovable 50x60 mm mass in the RA. Based on histological findings of subcutaneous tumors in the right abdominal wall, he was diagnosed as malignant lymphoma (ML), and treated with a THP-COP regimen. Upon completion of first THO-COP therapy, TEE showed marked regression of the mass and division into 3 masses, one of which showed marked floating movement with a small stalk. To prevent the risk of embolic events, surgical resection was performed. Resected tumors were necrotic tissues. Serial imaging of cardiac tumor and surgical resection is desirable to decrease the possibility of embolic complication. 相似文献
93.
Kihara Mari Sugihara Takahiko Asano Junichi Sato Midori Kaneko Hiroshi Muraoka Sei Ohshima Shiro Nanki Toshihiro 《Clinical rheumatology》2022,41(12):3661-3673
Clinical Rheumatology - To describe clinical characteristics of patients in Japan with coronavirus disease 19 (COVID-19) and pre-existing rheumatic disease and examine the possible risk factors... 相似文献
94.
Tomoyuki Sakai Toshihiro Sawai Yasuyo Shimizu Takao Morimune Yusuke Okuda Yoshihiro Maruo Sunao Iyoda Yoshihiro Takeuchi 《Pediatrics international》2015,57(5):1001-1003
Non‐O157 Shiga toxin‐producing Escherichia coli (STEC) strains are increasingly recognized as foodborne pathogens that trigger hemolytic uremic syndrome (HUS). The detection and isolation of these strains is important, but distinguishing their bacteriological profiles is difficult. A 2‐year‐old girl developed HUS with mild renal involvement 22 days after consuming barbecued meat. Clinical and laboratory findings gradually improved without specific treatment. Because neither enterohemorrhagic E. coli (EHEC) nor Shiga toxins were detected in stool cultures in a clinical laboratory and the patient tested negative for circulating antibodies to O157 lipopolysaccharide, the case was initially diagnosed as probable atypical HUS. Subsequent serodiagnostic microagglutination assay and polymerase chain reaction‐based molecular testing, however, indicated the presence of the EHEC O121:H19 strain with stx2. Thus, to correctly diagnose and treat HUS, a system for detecting non‐O157 STEC in a clinical setting is urgently needed. 相似文献
95.
Helicobacter pylori infection has been found to decrease the expression of antral somatostatin and to increase the release of the acid-stimulating
hormone gastrin. The reversal of these changes in gut hormones by the eradication of H. pylori, and in-vivo and in-vitro studies in animals either infected with H. pylori or exposed to H. pylori-related materials may support the somatostatin-gastrin link theory in the pathophysiology of H. pylori infection. The following mechanisms have been proposed to explain the H. pylori infection-associated changes in gut hormones; (1) ammonia produced by H. pylori and monochloramine, (2) effect on somatostatin receptor subtype-2, (3) action of lipopolysaccharide from H. pylori on somatostatin receptor, (4) inflammatory cells and mediators, and (5) bacterial strain diversity. H. pylori infection can alter gastric acid secretion in both directions. The elevated acid secretion in patients with duodenal ulcer
is decreased by H. pylori eradication, and is accompanied by the normalization of gut hormones in patients whose H. pylori-induced gastritis is limited to the antrum with hyperacidity. Corpus gastritis and the subsequent development of mucosal
atrophy induced by H. pylori result in decreased acid secretion, although the mechanism underlying H. pylori-induced atrophy in some subjects remains unclear. Hypoacidity enhances corpus atrophy and increases gastrin secretion, mediated
via a physiological suppression of somatostatin release, features that are also observed in H. pylori infection. Therefore, the capacity of acid secretion and distribution of gastritis or atrophy should be taken into consideration
when we discuss the affect of H. pylori on gut hormones.
Received: October 1, 2001 / Accepted: November 30, 2001 相似文献
96.
Teruo Nakamura Tadashi Takeuchi Akinori Terada Yusuke Tando Toshihiro Suda 《Journal of gastrointestinal cancer》1998,23(2):137-143
Summary
Conclusion. Near-infrared spectrometry is a new, rapid, and accurate method for measuring fecal fat that does not require
a great deal of chemical knowledge and that can be used by anyone. This method is considered indispensable for the diagnosis
of pancreatic steatorrhea and treatment follow-up.
Methods. Fecal fats (GLC method, van de Kamer method), neutral sterols (GLC method), bile acids (GLC method) and short-chain fatty
acids (HPLC method) were assayed by the respective conventional methods in 120 subjects, including patients with pancreatic
dysfunction, and the results were compared with the those obtained by near-infrared spectrometry. The correlations between
fecal fat excretion measured by the GLC method (x) and van de Kamer method (x) and by near-infrared spectrometry (y) were expressed by y=1.10 x-0.16 (r=0.949, P<0.01) and y=0.750x+1.654 (r=0.930, p<0.01), respectively.
Results. The sensitivity and specificity of near-infrared spectrometry for fecal fats were 94.9 and 98.2%, respectively, when compared
with the GLC method, and 87.5 and 90.0%, respectively, when compared with the van de Kamer method. In contrast, near-infrared
spectrometry was not nearly as accurate as the conventional methods for determining neutral sterols, bile acids, and short-chain
fatty acids. 相似文献
97.
Effects of cyclosporin A on water-immersion stress-induced gastric lesion and gastric secretion in rats 总被引:1,自引:0,他引:1
Odashima M Otaka M Ito S Iwabuchi A Wada I Konishi N Pacheco I Sato T Kato S Watanabe S 《Journal of gastroenterology》2000,35(5):369-371
Cyclosporin A is an immunosuppressive agent which is well known as a specific inhibitor of calcineurin (protein phosphatase
2B). In this study, we investigated the effects of cyclosporin A on water-immersion stress-induced gastric ulcer formation
and gastric acid secretion in rats. We also examined the localization of calcineurin immunohistochemically. Calcineurin was
specifically expressed in gastric parietal cells and chief cells of the gastric mucosa. The intraperitoneal administration
of cyclosporin A dose-dependently suppressed the development of gastric mucosal lesions induced by water-immersion stress
and inhibited gastric acid secretion, as assessed by pylorus ligation. These results indicated that calcineurin may play an
important role in gastric acid secretion.
Received: October 14, 1999 / Accepted: January 28, 2000 相似文献
98.
99.
Noriko Miyake Yong Chong Ruriko Nishida Katsuto Takenaka Koji Kato Toshihiro Miyamoto Akio Aono Akiko Takaki Satoshi Mitarai Shinji Shimoda Nobuyuki Shimono Koichi Akashi 《Journal of infection and chemotherapy》2018,24(1):78-81
In patients undergoing allogeneic hematopoietic stem cell transplantation (allo-SCT), post-transplant lung infection is critical for their prognosis. Mycobacterium abscessus complex is not fully recognized as a nontuberculous mycobacteria (NTM) pathogen of post-SCT lung infection. Here, we present three post-allogeneic SCT patients who developed pulmonary infection caused by M. abscessus complex including M. abscessus and M. massiliense. In all three cases, macrolide antibiotics had been administered for bronchiolitis obliterans syndrome (BOS) before the confirmation of their infection, and macrolide resistance was noted in the M. abscessus isolates, one of which resulted in an unfavorable treatment outcome. It is important to consider M. abscessus lung infection as well as other NTM in patients receiving allo-SCT, particularly those receiving macrolide therapy for BOS. 相似文献
100.
Shizuha Yabuki Hiroaki Toyama Yusuke Takei Toshihiro Wagatsuma Hiroshi Yabuki Masanori Yamauchi 《Journal of clinical monitoring and computing》2018,32(1):127-132
We tested the hypothesis that the environmental noise generated by a forced-air warming system reduces the monitoring accuracy of acoustic respiration rate (RRa). Noise levels were adjusted to 45–55, 56–65, 66–75, and 76–85 dB. Healthy participants breathed at set respiration rates (RRset) of 6, 12, and 30/min. Under each noise level at each RRset, the respiration rates by manual counting (RRm) and RRa were recorded. Any appearance of the alarm display on the RRa monitor was also recorded. Each RRm of all participants agreed with each RRset at each noise level. At 45–55 dB noise, the RRa of 13, 17, and 17 participants agreed with RRset of 6, 12, and 30/min, respectively. The RRa of 14, 17, and 16 participants at 56–65 dB noise, agreed with RRset of 6, 12, and 30/min, respectively. At 66–75 dB noise, the RRa of 9, 15, and 16 participants agreed with RRset of 6, 12, and 30/min, respectively. The RRa of one, nine, and nine participants at 76–85 dB noise agreed with RRset of 6, 12, and 30/min, respectively, which was significantly less than the other noise levels (P?<?0.05). Overall, 72.9% of alarm displays highlighted incorrect values of RRa. In a noisy situation involving the operation of a forced-air warming system, the acoustic respiration monitoring should be used carefully especially in patients with a low respiration rate. 相似文献