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31.
Aliyev Vusal Tokmak Handan Goksel Suha Meric Serhat Acar Sami Kaya Hakan Asoglu Oktar 《Journal of robotic surgery》2020,14(4):655-661
Journal of Robotic Surgery - Robotic surgery became more popularly in the colorectal surgical field. The aim of the study was to evaluate of the oncological outcomes which patients who underwent... 相似文献
32.
Zuhal Karagoz Genc Sibel Selcuk Suleyman Sandal Naki Colak Serhat Keser Memet Sekerci Mustafa Karatepe 《Medicinal chemistry research》2014,23(5):2476-2485
Novel six Cu(II), Ni(II), and Zn(II) complexes with Schiff bases derived from 4-aminobenzoic acid with terephtaldehyde and amino acids (glycine, β-alanine). Structures have been proposed from elemental analysis, UV–Vis, IR, NMR, TGA, DTA, and magnetic measurements. Spectroscopic studies suggest that coordination occurs through azomethine nitrogen, hydroxyl group, and carbonyl oxygen of the ligands to the metal ions. The elemental analyses of the complexes where L is Schiff base ligands, are confined to the stoichiometry of the type M2L2(CH3COO)2 [M = Cu(II)]; and M2L(CH3COO)2 [M = Ni(II) and Zn(II)]. The cytotoxicity activities of the compounds against human breast carcinoma MCF-7 cell line have been studied. Ligands and their Zn(II) compounds inhibited cell proliferation of MCF-7 cancer cell lines in a dose- and time-dependent manner. The free radical scavenging activity was measured by 1,1-diphenyl-2-picryl-hydrazil. Our results show that the synthesized compounds induced oxidative damage by increasing the lipid peroxidation in yeast since MDA formation was increased, and it could be concluded that the synthesized compounds caused oxidative stress. In addition, the antioxidant activities of the synthesized compounds were very much lower than those of standard antioxidants. 相似文献
33.
Mehmet İlker Gökçe Parviz Hajıyev Evren Süer Yusuf Kibar Mesrur Selçuk Sılay Serhat Gürocak Hasan Serkan Doğan Hasan Cem Irkılata Tayfun Oktar Bülent Önal Erim Erdem Yüksel Cem Aygün Can Balcı Ahmet Rüknettin Arslan Cevdet Kaya Tarkan Soygür Şaban Sarıkaya Serdar Tekgül Berk Burgu 《The Journal of urology》2014
34.
Turker Tekin Erguzel Serhat Ozekes Selahattin Gultekin Nevzat Tarhan 《Psychiatry investigation》2014,11(3):243-250
Objective
Many applications such as biomedical signals require selecting a subset of the input features in order to represent the whole set of features. A feature selection algorithm has recently been proposed as a new approach for feature subset selection.Methods
Feature selection process using ant colony optimization (ACO) for 6 channel pre-treatment electroencephalogram (EEG) data from theta and delta frequency bands is combined with back propagation neural network (BPNN) classification method for 147 major depressive disorder (MDD) subjects.Results
BPNN classified R subjects with 91.83% overall accuracy and 95.55% subjects detection sensitivity. Area under ROC curve (AUC) value after feature selection increased from 0.8531 to 0.911. The features selected by the optimization algorithm were Fp1, Fp2, F7, F8, F3 for theta frequency band and eliminated 7 features from 12 to 5 feature subset.Conclusion
ACO feature selection algorithm improves the classification accuracy of BPNN. Using other feature selection algorithms or classifiers to compare the performance for each approach is important to underline the validity and versatility of the designed combination. 相似文献35.
Taner Akar Mustafa Karapirli Ramazan Akcan Birol Demirel Barış Akduman Ahmet Zahit Dursun Serhat Sari Alper Özkök 《Archives of gerontology and geriatrics》2014
According to World Health Organization, the life expectancy at birth is increasing. An increase in life expectancy might result in increased morbidity and mortality in elderly. The increase in the elderly population also leads to an increase in medico-legal problems, as well. Autopsy is of high importance for determination of cause of death in clinical and forensic cases. The purpose of this study was to find out general characteristics elderly deaths by examining forensic autopsy records. 相似文献
36.
37.
Zeki Aydin Meltem Gursu Serhat Karadag Sami Uzun Abdullah Sumnu Yasemin Doventas 《Renal failure》2014,36(8):1253-1257
Introduction: Hepcidin, a small peptide hormone synthesized in the liver, plays central role in regulation of iron metabolism. Hepcidin generation in chronic kidney disease (CKD) is dependent on iron status, anemia, inflammation, and hypoxia and erythropoietin levels. In our study, the relationship between Prohepcidin levels and inflammation and iron indices in non-diabetic uremic patients was investigated. Methods: This study has a cross-sectional design which includes four groups: Non-diabetic 21 patients with stage 4 CKD (predialysis), 20 hemodialysis (HD) and 21 peritoneal dialysis (PD) patients and 17 healthy volunteers as the control group. Complete blood count, iron, total iron binding capacity (TIBC), ferritin, high-sensitive C-reactive protein (hsCRP), fibrinogen, parathyroid hormone, interleukin (IL)-6 and Prohepcidin levels were recorded. Results: Serum Prohepcidin levels in the predialysis, HD, PD and the control groups were 119.6?±?45.1?ng/mL, 140.2?±?41.8?ng/mL, 148.2?±?35.0?ng/mL and 93.8?±?21.9?ng/mL, respectively (p?0.001). Prohepcidin was positively correlated with urea (r?=?0.345, p?=?0.002), creatinine (r?=?0.465, p?0.001), phosphorus (r?=?0.253, p?=?0.025), hsCRP (r?=?0.275, p?=?0.019), duration of dialysis treatment (r?=?0.443, p?0.001), fibrinogen (r?=?0.467, p?0.001) and IL-6 (r?=?0.615, p?0.001) levels. A negative correlation was detected between Prohepcidin levels and albumin (r?=??0.286, p?0.001), TIBC (r?=??0.573, p?0.001), GFR (r?=??0.473, p?0.001), hemoglobin (r?=??0.351, p?=?0.002) and hematocrit (r?=??0.342, p?=?0.002) levels. Discussion: Prohepcidin levels increase with deepening anemia and show positive correlation with inflammatory markers. Therapeutic interventions regarding Prohepcidin action on inflammatory status may play a role in the treatment of anemia due to inflammation. Functional iron deficiency is frequent in uremic patients. It may be beneficial to measure Prohepcidin level together with ferritin among these patients. 相似文献
38.
Predictors of in‐hospital mortality in octogenarian patients who underwent primary percutaneous coronary intervention after ST segment elevated myocardial infarction
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39.
Marta?Ferrer Isabelle?Boccon-Gibod Margarida?Gon?alo Hüseyin?Serhat??nal?z André?Knulst Hilde?Lapeere Anchala?Parthasaradhi Georg?Stingl Anna?Tagka Fernando?Valenzuela Jensen?Yeung Simon?Francis?ThomsenEmail author 《European journal of dermatology : EJD》2017,27(5):455-463
Omalizumab (a recombinant, humanized anti-immunoglobulin-E anti-body) has been shown in three pivotal Phase III trials (ASTERIA I, II and GLACIAL) and real-world studies to be effective and well-tolerated for the treatment of chronic spontaneous urticaria (CSU), and is the only licensed third-line treatment for CSU. However, the definition of response to omalizumab treatment often differs between clinical trials, real-world studies, and daily practice of individual physicians globally. As such, a consensus definition of “complete”, “partial” and “non-response” to omalizumab is required in order to harmonize treatment management and compare data. Here, it is proposed that a disease measurement tool, for example, the 7-Day Urticaria Activity Score (UAS7) or Urticaria Control Test (UCT) is required for defining response. The addition of quality of life measurements is helpful to gain insight into a patient’s disease burden and its changes during treatment. A potential omalizumab treatment approach based on speed and pattern of response at 1-3 and 3-6 months is suggested. In cases where there is no response during the first 1-3 months, physicians should consider reassessing the original CSU diagnosis. Moreover, in patients showing partial response at 12 weeks, treatment with omalizumab should be continued in order to maximize the possibility of achieving symptom control. If patients have a UAS7>6 and/or UCT<12, then continued treatment is advised, dependent on physician judgement and patient expectations. In treatment responders, omalizumab treatment can be resumed at a later stage after discontinuation with the same degree of symptom control. 相似文献
40.
Huseyin Ayhan Kayaoglu Namik Ozkan Selcuk Mevlut Hazinedaroglu Omer Faik Ersoy Ayhan Bulent Erkek Resit Dogan Koseoglu 《Journal of investigative surgery》2013,26(2):89-95
This experimental study was designed to assess and to compare intra-abdominal adhesions following the use of five commercially available prosthetic mesh grafts in the repair if abdominal wall defects. Sixty Wistar albino rats were randomly divided into six groups (n = 10). A 2 × 1 cm defect at abdominal wall was created and defects were closed either primarily or with one of the following prosthetic mesh grafts: monofilament polypropylene, polytetrafluoroethylene, sodium hyaluronate/carboxymethylcellulose-coated polypropylene, polypropylene/polyglactin 910 composite, or resorbable hydrophilic collagen-coated multifiber polyester. The severity of adhesions was graded, tensile strengths of adhesions were measured, and histopathological grades of inflammation and fibrosis were evaluated. Polypropylene mesh resulted in more adhesion formation in comparison to primary repair and other grafts used in this study, except polypropylene/polyglactin 910 composite mesh. In addition, the highest tensile strength of omental adhesions was detected in the polypropylene group (χ2 = 26.249; p =. 0001). Polyester composite mesh caused the least adhesion formation among the groups. Sodium hyaluronate/carboxymethylcellulose-coated polypropylene and polyester composite meshes revealed the highest fibrosis scores (χ2 = 50.776; p =. 0001). The highest inflammatory activity was detected in the polytetrafluoroethylene mesh group (χ2 = 16.564; p =. 005). Thus, sodium hyaluronate/carboxymethylcellulose-coated polypropylene and polytetrafluoroethylene meshes following polyester composite mesh were the minimal adhesion-forming grafts in this study. Disadvantages of the polytetrafluoroethylene mesh were lower fibrotic activity and higher inflammatory reaction to the graft. 相似文献