全文获取类型
收费全文 | 66275篇 |
免费 | 4765篇 |
国内免费 | 349篇 |
专业分类
耳鼻咽喉 | 690篇 |
儿科学 | 1652篇 |
妇产科学 | 1597篇 |
基础医学 | 8132篇 |
口腔科学 | 1638篇 |
临床医学 | 6607篇 |
内科学 | 15094篇 |
皮肤病学 | 870篇 |
神经病学 | 5176篇 |
特种医学 | 2052篇 |
外国民族医学 | 2篇 |
外科学 | 10453篇 |
综合类 | 1056篇 |
现状与发展 | 1篇 |
一般理论 | 103篇 |
预防医学 | 5404篇 |
眼科学 | 1908篇 |
药学 | 4582篇 |
中国医学 | 143篇 |
肿瘤学 | 4229篇 |
出版年
2023年 | 321篇 |
2022年 | 514篇 |
2021年 | 1264篇 |
2020年 | 767篇 |
2019年 | 1098篇 |
2018年 | 1339篇 |
2017年 | 922篇 |
2016年 | 1045篇 |
2015年 | 1217篇 |
2014年 | 1906篇 |
2013年 | 2946篇 |
2012年 | 3954篇 |
2011年 | 4346篇 |
2010年 | 2478篇 |
2009年 | 2312篇 |
2008年 | 4169篇 |
2007年 | 4367篇 |
2006年 | 4175篇 |
2005年 | 4242篇 |
2004年 | 3977篇 |
2003年 | 3571篇 |
2002年 | 3543篇 |
2001年 | 774篇 |
2000年 | 679篇 |
1999年 | 767篇 |
1998年 | 767篇 |
1997年 | 625篇 |
1996年 | 509篇 |
1995年 | 503篇 |
1994年 | 482篇 |
1993年 | 453篇 |
1992年 | 548篇 |
1991年 | 535篇 |
1990年 | 440篇 |
1989年 | 465篇 |
1988年 | 423篇 |
1987年 | 400篇 |
1986年 | 371篇 |
1985年 | 439篇 |
1984年 | 452篇 |
1983年 | 403篇 |
1982年 | 538篇 |
1981年 | 448篇 |
1980年 | 488篇 |
1979年 | 305篇 |
1978年 | 331篇 |
1977年 | 326篇 |
1976年 | 266篇 |
1975年 | 298篇 |
1974年 | 251篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
131.
Hugh E. Criswell Darin J. Knapp David H. Overstreet George R. Breese 《Alcoholism, clinical and experimental research》1994,18(3):596-601
The effects of ethanol, chlordiazepoxide, and MK-801 on performance in the elevated-plus maze and on activity measured in a circular activity monitor were compared in Sprague-Dawley rats to determine whether these effects of ethanol could be explained by its action on either GABAA or NMDA receptors. Both ethanol and chlordiarepoxide produced an increase in the time spent in the open arms of the elevated-plus maze and in the ratio of open arm to total arm entries, indicative of an anxiolytic action of these drugs. MK-801 did not alter either the time spent in the open arms or the ratio of open to total arm entries. Chlordiazepoxide and MK-801 produced an increase in total arm entries that suggested that these compounds were increasing locomotor activity. Ethanol also increased total arm entries, but the effect was not statistically reliable. Following habituation to an activity monitor, neither ethanol nor chlordiazepoxide increased activity in this task, whereas MK-801 produced a robust increase in locomotion. Additionally, neither ethanol nor chlordiazepoxide blocked the MK-801-induced locomotor stimulation. The latter finding suggests that the effects of ethanol on GABAA receptors was not Mocking an increased activity level produced by its antagonism of NMDA. Additionally, these results indicate that the anxiolytic and locomotor action of ethanol in rats parallel the effects of a benzodiazepine and not those of an NMDA antagonist. Finally, these results suggest that the consequence of ethanol's antagonism of NMDA receptor function is more restricted than that produced by MK-801. 相似文献
132.
The postoperative necrotizing sclerokeratitis is a rare condition occurring shortly after surgical procedures, mainly following cataract extractions. After several exacerbations and remissions spontaneous scleral perforation may occur. In the described case the conservative treatment/topical antibiotics, corticosteroids/failed, therefore the damaged scleral surface was covered with lyophilized dura and the condition came to a standstill. 相似文献
133.
134.
135.
George D Veenhuyzen 《Journal of the American College of Cardiology》2006,48(2):418-9; author reply 419
136.
137.
138.
George M. Smith H.David Shine 《International journal of developmental neuroscience》1992,10(5):387-392
Tight junctions may play an important role in maintaining the integrity of the blood-brain barrier. These junctions can be individually visualized using electron microscopy but no current technique is able to provide a more global picture of the presence and density of tight junctions in central nervous system tissue. We used an antibody that recognizes a high molecular weight protein (ZO-1) associated with tight junctions, to identify these specialized junctions within the rat brain and spinal cord. Immunofluorescent labeling showed a network of tight junctions between cells in the brain vasculature, leptomeninges and choroid plexus, and between tanycytes lining the floor of the third ventricle and the central canal of the spinal cord. Anti-ZO-1 labeled the majority of cells associated with the blood-brain barrier and may prove a useful marker, possibly in conjunction with functional dye studies, in evaluating the anatomical and functional integrity of the blood-brain barrier. 相似文献
139.
140.
Pierre man John Gordon Hkan Mellstedt Peter Biberfeld George Klein 《European journal of haematology》1988,40(2):142-148
Leukemic cells from a series of patients with chronic B-lymphocytic leukemia (CLL) were analyzed for their buoyant density on discontinuous Percoll gradients. The density profile varied markedly between different patients and also between samples from different body compartments within the same patient. A good correlation was observed between buoyant density and maturation stage of the leukemic clones as judged by Ig-expression and their reactivity with a panel of monoclonal antibodies. Phorbol-ester-induced changes in the leukemic cells were found to be accompanied by a general decrease in their buoyant density. No correlation between density and clinical parameters such as cell counts, clinical stage and survival could be noted. Buoyant density characterization of leukemic B-cell populations is seen as a useful, rapid and simple marker of compartmentalization within the B-lymphocyte maturation spectrum but its clinical relevance remains to be established. 相似文献