全文获取类型
收费全文 | 2391篇 |
免费 | 123篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 67篇 |
儿科学 | 92篇 |
妇产科学 | 64篇 |
基础医学 | 206篇 |
口腔科学 | 99篇 |
临床医学 | 173篇 |
内科学 | 489篇 |
皮肤病学 | 16篇 |
神经病学 | 220篇 |
特种医学 | 210篇 |
外科学 | 343篇 |
综合类 | 96篇 |
一般理论 | 4篇 |
预防医学 | 162篇 |
眼科学 | 46篇 |
药学 | 122篇 |
中国医学 | 11篇 |
肿瘤学 | 102篇 |
出版年
2023年 | 19篇 |
2022年 | 83篇 |
2021年 | 88篇 |
2020年 | 52篇 |
2019年 | 57篇 |
2018年 | 91篇 |
2017年 | 67篇 |
2016年 | 71篇 |
2015年 | 84篇 |
2014年 | 100篇 |
2013年 | 137篇 |
2012年 | 161篇 |
2011年 | 158篇 |
2010年 | 103篇 |
2009年 | 76篇 |
2008年 | 125篇 |
2007年 | 137篇 |
2006年 | 158篇 |
2005年 | 127篇 |
2004年 | 109篇 |
2003年 | 111篇 |
2002年 | 80篇 |
2001年 | 39篇 |
2000年 | 52篇 |
1999年 | 33篇 |
1998年 | 9篇 |
1997年 | 8篇 |
1996年 | 4篇 |
1995年 | 9篇 |
1994年 | 8篇 |
1993年 | 6篇 |
1992年 | 15篇 |
1991年 | 6篇 |
1990年 | 11篇 |
1989年 | 11篇 |
1988年 | 8篇 |
1987年 | 8篇 |
1985年 | 6篇 |
1984年 | 6篇 |
1983年 | 9篇 |
1980年 | 4篇 |
1979年 | 6篇 |
1978年 | 4篇 |
1973年 | 6篇 |
1972年 | 6篇 |
1971年 | 7篇 |
1970年 | 3篇 |
1968年 | 6篇 |
1967年 | 4篇 |
1965年 | 5篇 |
排序方式: 共有2522条查询结果,搜索用时 15 毫秒
21.
22.
Jing Ying Lim Roslee Rajikan Noh Amit Nazlena Mohamad Ali Haslina Abdul Hamid Huey Yin Leong Maslina Mohamad Bi Qi Koh Aini Musa 《Nutrients》2022,14(12)
Dietary intervention is generally accepted as the mainstay of treatment for patients with disorders of amino acid metabolism (AAMDs). However, dietary adherence to a low-protein diet is always reported as a common challenge among these patients. This study explored the perception of barriers and motivators to dietary adherence among caregivers of AAMD patients in Malaysia. Twenty caregivers of children with AAMDs receiving ongoing treatment at the genetic clinic participated in an online focus group discussion from November to December 2021. Findings showed a total of five interrelated main themes identified from focus group discussion (FGD) exploring parents’ experiences related to the management of their child’s daily diet. The barriers to dietary adherence were burden of dietary treatment, diet and dietary behavior, parenting challenges, limited knowledge related to dietary treatment, and challenges in healthcare system delivery. Key factors facilitating good dietary adherence include good knowledge of dietary treatment, parental coping strategies, social coping, and dietary behavior. In conclusion, despite the existence of several barriers to the implementation of dietary treatment, caregivers managed to use a wide range of coping strategies to overcome some, if not all, of the challenges. The important next step is to develop, in conjunction with multidisciplinary healthcare professionals, feasible implementation strategies that could address these barriers and at the same time improve the quality of life of caregivers. 相似文献
23.
Serbeze Kabashi Ilir Ahmetgjekaj Edlira Harizi Fjolla Hyseni Erisa Kola Valon Vokshi Guri Hyseni Ina Kola Humza Haroon Masum Rahman Kledisa Shemsi Arlind Decka Livia Capi Kaltrina Goaj Juna Musa 《Radiology Case Reports》2022,17(9):2940
Tumors of the pineal region are a rare clinical entity, comprising approximately 3%-8% of pediatric tumors. Based on their histopathological features, they are typically classified as pineal parenchymal tumors and germ cell tumors, with the latter being more prevalent. Clinical presentation is heterogeneous, with symptoms arising either due to tumor invasion or compression of adjacent neurovascular structures and increased intracranial pressure. Imaging studies are paramount in evaluating pineal region lesions and establishing an accurate diagnosis, with MRI representing the gold standard. Herein, we present the case of a 16-year-old boy presented with recurrent headaches. A head MRI revealed a pineal gland lesion. Histopathological examination confirmed the diagnosis, and the patient underwent a successful gross total resection (GTR) of the tumor. This case report seeks to draw attention to the elusive clinical presentation and management of this infrequently encountered tumor, as well as emphasize the importance of considering pineal gland tumors in the differential diagnosis of recurrent, chronic headaches in pediatric patients. 相似文献
24.
Erturhan S Seçkiner I Zincirkeser S Erbagci A Celik M Yagci F Karakok M 《Annals of nuclear medicine》2008,22(3):225-229
Primary renal synovial sarcoma is a rarely seen renal neoplasm. An experienced uropathologist is needed to make the pathological diagnosis. A patient, operated on with a prediagnosis of renal cell carcinoma, the pathology of which was reported as synovial sarcoma, is presented in this article. 18F-fluoro-deoxyglucose positron emission tomography and computed tomography were performed preoperatively and in the postoperative follow-up to detect the primary tumor and lymph node metastases. 相似文献
25.
Vladimir Carli Peter Parzer Camilla Wasserman Birgitta Floderus Alan Apter Judit Balazs Shira Barzilay Julio Bobes Romuald Brunner Paul Corcoran Doina Cosman Padraig Cotter Romain Despalins Nadja Graber Francis Guillemin Christian Haring Jean‐Pierre Kahn Laura Mandelli Dragan Marusic Gergely Mészáros George J. Musa Vita Postuvan Franz Resch Pilar A. Saiz Merike Sisask Airi Varnik Marco Sarchiapone Christina W. Hoven Danuta Wasserman 《Addiction (Abingdon, England)》2012,107(12):2210-2222
26.
Daniel J. Stein Christian Salinas Saher Sabri Rose Onyeali Stephen Caldwell Zachary Henry 《Journal of vascular and interventional radiology : JVIR》2019,30(2):187-194
Purpose
To assess short- and long-term mortality and rebleeding with endoscopic cyanoacrylate (EC) versus balloon-occluded retrograde transvenous obliteration (BRTO).Materials and Methods
A retrospective cohort comparison was conducted of 90 EC patients and 71 BRTO patients from 1997 through 2015 with portal hypertension who presented due to endoscopically confirmed bleeding cardiofundal gastric varices. Patients underwent either endoscopic intra-varix injection of 4-carbon-n-butyl-2-cyanoacrylate or sclerosis with sodium tetradecyl sulfate with balloon occlusion for primary variceal treatment.Results
Seventy-one BRTO patients and 90 EC patients, of whom 89% had cirrhosis and 35% were women, were included, with a respective average Model for End-Stage Liver Disease (MELD) score of 13.4 and 14.4, respectively. Mortality at 6 weeks was 14.4% for EC patients and 13.1% for BRTO patients (Kaplan-Meier/Wilcoxon, P = .85). No long-term mortality difference was observed (Cox hazard ratio [HR] = 0.89, P = .64). Also, 5.1% of EC patients and 3.5% of BRTO patients (Kaplan-Meier/Wilcoxon, P = .62) rebled at 6 weeks, but at 1 year, 22.0% of EC patients and 3.5% of BRTO patients had rebled (Kaplan-Meier/Wilcoxon, P < .01). Lower rates of long-term rebleeding were found with BRTO (Cox HR = 0.25, P = .03). No difference was seen in the rate of new portal hypertensive complications (Cox HR = 1.21, P = .464). However, 16/71 patients who underwent BRTO had simultaneous transjugular intrahepatic portosystemic shunt. Age, sex, MELD score, and presence of cirrhosis were the primary predictors of mortality. One death in the EC group and 5 deaths in the BRTO group were deemed to be procedurally related (chi-square, P = .088).Conclusions
BRTO is associated with a lower rate of rebleeding but no change in mortality. 相似文献27.
28.
Willie M. U. Daniels Ianthe L. Pitout Thomas J. O. Afullo Musa V. Mabandla 《Metabolic brain disease》2009,24(4):629-641
Electromagnetic radiation (EMR) is emitted from electromagnetic fields that surround power lines, household appliances and
mobile phones. Research has shown that there are connections between EMR exposure and cancer and also that exposure to EMR
may result in structural damage to neurons. In a study by Salford et al. (Environ Health Perspect 111:881–883, 2003) the authors demonstrated the presence of strongly stained areas in the brains of rats that were exposed to mobile phone
EMR. These darker neurons were particularly prevalent in the hippocampal area of the brain. The aim of our study was to further
investigate the effects of EMR. Since the hippocampus is involved in learning and memory and emotional states, we hypothesised
that EMR will have a negative impact on the subject’s mood and ability to learn. We subsequently performed behavioural, histological
and biochemical tests on exposed and unexposed male and female rats to determine the effects of EMR on learning and memory,
emotional states and corticosterone levels. We found no significant differences in the spatial memory test, and morphological
assessment of the brain also yielded non-significant differences between the groups. However, in some exposed animals there
were decreased locomotor activity, increased grooming and a tendency of increased basal corticosterone levels. These findings
suggested that EMR exposure may lead to abnormal brain functioning. 相似文献
29.
Gurkan Ozturk Kamil Yalcin Polat Mehmet Ilhan Yildirgan Bulent Aydinli Sabri Selcuk Atamanalp Unal Aydin 《Journal of gastroenterology and hepatology》2009,24(8):1365-1369
Background and Aim: Hepatic alveolar echinococcosis (HAE) involves both the vascular and biliary structures of the liver. Endoscopic retrograde cholangiopancreatography (ERCP) is said to be an alternative for the diagnosis and treatment of biliary complications of HAE. We present here our experience with ERCP in HAE.
Methods: We followed 13 patients who underwent ERCP for the treatment of biliary complications of HAE in the endoscopy unit of our clinic at Ataturk University School of Medicine, Erzurum between January 2002 and June 2008.
Results: Eight men and five women were followed up. Mean age was 43.2 (24–64 years). All patients had non-resectable HAE. Indications for ERCP were biliary fistula in seven patients, obstructive jaundice in five patients and cholangitis in one patient. Endoscopic sphincterotomy (ES) was carried out in 12 patients, and in one patient with biliary leakage, a stent was inserted into the right hepatic branch. ERCP findings were dilated common bile duct, irregular narrowing and distortion of the common bile duct and common hepatic duct, communication with the cystic cavity or biliocutaneous fistula and complete disappearance of the biliary tree above the level of the common hepatic duct or hepatic bifurcation. In patients with biliary leakage, biliary drainage decreased only in two patients after ERCP and in patients with obstructive jaundice, the high bilirubin levels decreased in only one patient.
Conclusion: ERCP showed structural changes of the external biliary tract and ES has a limited effect on these changes and stents can be used in selected cases. 相似文献
Methods: We followed 13 patients who underwent ERCP for the treatment of biliary complications of HAE in the endoscopy unit of our clinic at Ataturk University School of Medicine, Erzurum between January 2002 and June 2008.
Results: Eight men and five women were followed up. Mean age was 43.2 (24–64 years). All patients had non-resectable HAE. Indications for ERCP were biliary fistula in seven patients, obstructive jaundice in five patients and cholangitis in one patient. Endoscopic sphincterotomy (ES) was carried out in 12 patients, and in one patient with biliary leakage, a stent was inserted into the right hepatic branch. ERCP findings were dilated common bile duct, irregular narrowing and distortion of the common bile duct and common hepatic duct, communication with the cystic cavity or biliocutaneous fistula and complete disappearance of the biliary tree above the level of the common hepatic duct or hepatic bifurcation. In patients with biliary leakage, biliary drainage decreased only in two patients after ERCP and in patients with obstructive jaundice, the high bilirubin levels decreased in only one patient.
Conclusion: ERCP showed structural changes of the external biliary tract and ES has a limited effect on these changes and stents can be used in selected cases. 相似文献
30.