998.
The electrocardiogram was continuously recorded during a two and a half hour period of driving in 65 normal subjects and in 66 subjects with documented coronary heart disease.
In normal subjects, except for a variable increase in heart rate, no significant changes were observed.
Among the subjects with coronary heart disease, significant electrocardiographic changes, i.e., ischemic type of S-T depression, multifocal premature contractions, ventricular bigeminal or trigeminal rhythm, were observed in 16.7 per cent. These changes occurred under relatively favorable driving conditions. The relation of such changes to the occurrence of accidents on the highway merits further study. The magnitude of this problem is indicated by the large number of subjects with coronary heart disease who drive. 相似文献