脊髓损伤患者泌尿系感染的病原学特点及耐药性分析

目的 探讨脊髓损伤(SCI)患者泌尿系感染(UTI)的病原学特点及耐药情况,并分析不同膀胱排空方式SCI患者UTI病原菌在构成及耐药性方面的差异,为临床治疗提供依据.方法 收集2013年1月-2019年12月于我院康复医学科确诊为UTI且尿培养阳性的SCI患者190例作为SCI组,以泌尿外科确诊为UTI且尿培养阳性的非...     

现代眩晕医案中情志症名的文献分析

目的:检索1949～2010年中国出版的有关眩晕的医案文献,分析规范化后情志失常的研究,为临床病例信息调查表的制作提供可靠的依据。方法:以中国学术期刊网络出版社总库为主要来源,共检索到1 296篇符合描述眩晕症状的医案文献。运用Note Express软件和Excel 2003从医案中截取症状归类排序和频数统计,并运用统一标准的症状术语进行规范化,统计规范化后的有关情志失常的症状。结果:眩晕医案中烦躁、善怒、心烦、健忘、善悲、善忧思等18种症状共累计出现143篇,占医案总篇数13.06%,为眩晕病案中情志失常的症状进行初步症名的规范化,满足科研与临床的实际需要。结论:规范眩晕病案中情志症状名称,有助于提高诊治眩晕的可操作性和辨证论治水平。     

Endothelium-independent relaxation and contraction of rat aorta induced by ethyl acetate extract from leaves of Morus alba (L.)

Aim of the study

Based on screening for vasoactive traditional Chinese medicinal herbs, the present study was performed to investigate the vasoactive effects of an ethyl acetate extract from leaves of Morus alba (L.) (ELM) on rat thoracic aorta and the mechanisms underlying these effects.

Materials and methods

Isolated rat thoracic rings were mounted in an organ bath system and the effects of ELM on their responses were evaluated.

Results

ELM (0.125–32.000 g/l) induced a concentration-dependent relaxation (P < 0.01 vs. control) both in endothelium-intact and -denuded aortas precontracted by high K⁺ (6 × 10⁻² M) or 10⁻⁶ M phenylephrine (PE). In endothelium-denuded aortas, ELM at the EC₅₀ concentration reduced Ca²⁺-induced contraction (P < 0.01 vs. control) after PE or KCl had generated a stable contraction in Ca²⁺-free solution. And after incubation with verapamil, ELM induced contraction in endothelium-denuded aortas precontracted by PE (P < 0.01 vs. control); this was abolished by ruthenium red (P < 0.01 vs. ELM-treated endothelium-denuded group; P > 0.05 vs. control), but not by heparin (P > 0.01 vs. ELM-treated endothelium-denuded group; P < 0.01 vs. control).

Conclusions

The results showed that ELM had dual vasoactive effects, and the relaxation was greater than the contraction. The relaxation was mediated by inhibition of voltage- and receptor-dependent Ca²⁺ channels in vascular smooth muscle cells, while the contraction occurred via activation of ryanodine receptors in the sarcoplasmic reticulum.     

含氢硅油表面接枝改性PET织物的拒水性能

通过接枝率、接触角、透水时间、拉伸应力应变、ＥＳＣＡ的测定以及不冲击实验研究了在ＤＣＰ和ＢＰ等存在下电晕放电引发含氢硅油接枝ＰＥＴ织物及其拒水性能,实验结果表明：电晕放电能有效引发含氢硅油在ＰＥＴ织物表面的接枝共聚反应,随电晕放电处理时间的延长,ＰＥＴ织物表面接枝率增大;接枝后ＰＥＴ织物拒水效果明显增强;电晕放电引发接枝改性后ＰＥＴ织物无损伤,力学性能基本保持不变。     

关于首次病程记录内容和格式的探讨

2002年4月卫生部颂发了<病历书写基本规范(试行)>(以下简称(<部规范>),并要求各地于同年9月1日起执行.因为<部规范>是一个纲领性文件,很多具体的书写格式和要求的细节均未能充分表述,如对首次病程记录书写内容的要求只是一句"首次病程记录的内容包括病例特点、诊断依据及鉴别诊断、诊疗计划等"[1].为便于临床参照执行以及加强病案质量管理,湖南省卫生厅2004年7月出版了<病历书写规范与管理规定及病例(案)医疗质量评定标准>(以下简称<省规范>).为便于临床质量控制,<省规范>在首次病程记录中增加了一项病例分型(病例分型标准:A型:一般病例:B型:一般急症病例;C型:疑难重症病例;D型:危重病例)[2].并对首次病程记录内容的表述略作改动:"首次病程记录的内容包括病例特点、诊断依据及鉴别诊断、病例分型及诊疗计划等"[3].并有如下"示例":     

PBL联合CBL教学法在急诊住院医师规范化培训教学中的应用

目的 探讨PBL联合CBL教学法在急诊住院医师规范化培训教学中的应用效果。方法 选择2019年3—6月在本科室参加住院医师规范化培训的80名学员,随机分为两组,各40名。其中对照组采用PBL教学方法,观察组采用PBL联合CBL教学方法授课。带教结束后,采用DOPS评分、Mini-CEX评分、技能操作和学员满意度调查问卷评估两组学员的教学成果。结果 与对照组相比,观察组学员DOPS各项指标及总分、教学满意度、Mini-CEX考核评分、急救技能操作成绩均高于对照组,且差异均有统计学意义（P <0.05）。结论 PBL联合CBL教学法在急诊住培教学中有助于提高学员的学习能力,提升急诊临床教学质量。     

三黄片在术后早期炎性肠梗阻治疗中的应用价值探讨

目的探讨三黄片在术后早期炎性肠梗阻治疗中的应用价值。方法对36例术后早期炎性肠梗阻患者的治疗进行回顾性总结。结果治疗组中18例患者经过保守治疗,痊愈15例,有效17例,有效率94．4％;对照组中18例治愈10例,有效率83．3％。结论三黄片在术后早期炎性肠梗阻治疗中具有一定的应用价值,值得推广。     

Integrating Patient Concerns into Parkinson’s Disease Management

Parkinson’s disease (PD) is a complex motor and non-motor disorder and management is often challenging. In this review, we explore emerging approaches to improve the care of patients, drawing from the literature regarding patient-centred care, patient and caregiver perspectives and priorities, gaps in knowledge among patients and caregivers and the need for accurate information, individual variability in disease manifestations, prognostication of disease course, new developments in health technologies and personalized medicine, specialty care, pharmacological and non-pharmacological management, financial burden, lifestyle and work-related issues, support groups and palliative care.