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61.
da Silva Barros Caio Csar de Souto Medeiros Maurlia Raquel de Azevedo Roberto Almeida da Costa Miguel Mrcia Cristina dos Santos Jean Nunes da Silveira ricka Janine Dantas 《Oral and maxillofacial surgery》2021,25(4):575-579
Oral and Maxillofacial Surgery - Peripheral dentinogenic ghost cell tumor (DGCT) is a rare and non-aggressive benign odontogenic tumor. They usually affect the elderly and are predominantly located... 相似文献
62.
Renata Nunes Cabral Bente Nyvad Vera Ligia Vieira Mendes Soviero Eduardo Freitas Soraya Coelho Leal 《Clinical oral investigations》2020,24(2):727-734
To describe a new molar-incisor hypomineralization (MIH) severity scoring system (MIH-SSS) that focuses on the defects’ severity and to assess the sy 相似文献
63.
Isabel Fragata Teresa Morais Rita Silva Ana Paiva Nunes Petra Loureiro Jos Diogo Martins Jaime Pamplona Rui Carvalho Mariana Baptista Joo Reis 《Interventional neuroradiology》2021,27(1):16
IntroductionMechanical thrombectomy is standard treatment for large vessel occlusion (LVO) in adults. There are no randomized controlled trials for the pediatric population. We report our single-center experience with thrombectomy of LVO in a series of pediatric patients, and perform a review of the literature.MethodsRetrospective review of consecutive pediatric thrombectomy cases between 2011 and 2018. Demographic variables, imaging data, technical aspects and clinical outcome were recorded.ResultsIn a period of 7 years, 7 children were treated for LVO at our center. Median age was 13 (2–17), and median Ped-NIHSS was 15 (3–24), and the median ASPECTS was 8 (2–10). Five patients had cardiac disease, and 2 of them were under external cardiac assistance. Median time from onset of symptoms to beginning of treatment was 7h06m (2h58m–21h38m). Five patients had middle cerebral artery occlusions. Thrombectomy was performed using a stentriever in 3 patients, aspiration in 3 patients, and combined technique in 1 patient. Six patients had good recanalization (TICI 2 b/3). There were no immediate periprocedural complications. At 3 months, 4 patients (57%) were independent (mRS score <3). Two patients died, one after haemorrhagic transformation of an extensive MCA infarct, and one due to extensive brainstem ischemia in the setting of varicella vasculitis.DiscussionSelected pediatric patients with LVO may be treated with mechanical thrombectomy safely. In patients under external cardiac assistance and under anticoagulation, thrombectomy is the only alternative for treatment of LVO. A multidisciplinary approach in specialized pediatric stroke centers with trained neurointerventionalists are essential for good results. 相似文献
64.
ST Hornby FD McDermott M Coleman Z Ahmed J Bunni D Bunting M Elshaer V Evans A Kimble M Kostalas G Page J Singh L Szczebiot S Wienand-Barnett A Wilkins O Williams P Newell Severn Peninsula Audit Research Collaborative 《Annals of the Royal College of Surgeons of England》2015,97(2):115-119
Background
Laparoscopic hernia repair is used widely for the repair of incisional hernias. Few case studies have focussed on purely ‘incisional’ hernias. This multicentre series represents a collaborative effort and employed statistical analyses to provide insight into the factors predisposing to recurrence of incisional hernia after laparoscopic repair. A specific hypothesis (ie, laterality of hernias as well as proximity to the xyphoid process and pubic symphysis predisposes to recurrence) was also tested.Methods
This was a retrospective study of all laparoscopic incisional hernias undertaken in six centres from 1 January 2004 to 31 December 2010. It comprised a comprehensive review of case notes and a follow-up using a structured telephone questionnaire. Patient demographics, previous medical/surgical history, surgical procedure, postoperative recovery, and perceived effect on quality of life were recorded. Repairs undertaken for primary ventral hernias were excluded. A logistic regression analysis was then fitted with recurrence as the primary outcome.Results
A total of 186 cases (91 females) were identified. Median follow-up was 42 months. Telephone interviews were answered by 115/186 (62%) of subjects. Logistic regression analyses suggested that only female sex (odds ratio (OR) 3.53; 95% confidence interval (CI) 1.39–8.97) and diabetes mellitus (3.54; 1–12.56) significantly increased the risk of recurrence. Position of the defect had no statistical effect.Conclusions
These data suggest an increased risk of recurrence after laparoscopic incisional hernia repair in females and subjects with diabetes mellitus. These data will help inform surgeons and patients when considering laparoscopic management of incisional hernias. We recommend a centrally hosted, prospectively maintained national/international database to carry out additional research. 相似文献65.
José Albuquerque de Figueiredo Neto Lívia Mariane Castelo Branco Reis Márcia Rodrigues Veras Lorena Lauren Chaves Queiroz Karine de Paiva Lima Nogueira Nunes Priscylla de Oliveira Miranda Alexsandro Ferreira dos Santos Joana Kátya Veras Rodrigues Sampaio Nunes 《Brazilian Journal Of Cardiovascular Surgery》2015,30(6):626-630
INTRODUCTION
The elderly population is growing rapidly. Political and socio-economic changes led to the demographic transition in this population with the highest number of surgeries and as well as many comorbidities.OBJECTIVE
To evaluate the impact of cardiovascular intervention on quality of life of elderly patients after three and six months.METHODS
Analytical prospective cohort study with elderly between 60 and 80 years of age, of both sexes, with a diagnosis of coronary artery disease and underwent cardiovascular intervention during the period June 2010 to June 2011. Data were collected by individual interviews in the pre and postoperative periods (after three and six months) by telephone. We used the SF-36 to analyse quality of life in order to assess the physical and mental health of the study population.RESULTS
Of the 44 individuals evaluated, 59.1% were men, 75% in the range of 65 to 74 years, 38.6% were white and 38.6% were black, 31.8% were uneducated, 43.2% were married and 68.2% had less than a minimum wage. Prevailed patients: non-diabetics (68.2%), non-obese (81.8%), hypertensive (84.1%), non-alcoholic and non-smokers (68.2% and 61.4%, respectively). A significant increase in the average of the SF-36 scores between pre and post-surgical periods (three and six months) for the domains: functional capacity, pain, general health, vitality and emotional aspect.CONCLUSION
The elderly population undergoing intervention may have cardiovascular benefits and improvements of quality of life. Physical fitness improvement measures can be taken to resume that capability. 相似文献66.
67.
Ng VL; Hurt MH; Fein CL; Khayam-Bashi F; Marsh J; Nunes WM; McPhaul LW; Feigal E; Nelson P; Herndier BG 《Blood》1994,83(4):1067-1078
Two B-cell lines, 2F7 and 10C9, were established by single cell cloning from biopsies obtained from two acquired immune deficiency syndrome patients with Burkitt's lymphoma. Representation of the original tumors was verified by demonstration of (1) identical biallelic rearrangement of Ig genes for 2F7 and (2) shared idiotype for 10C9. Both cell lines displayed cell-surface Ig and secreted Ig (IgM lambda for 2F7, IgM kappa for 10C9). IgMs from both cell lines immunoprecipitated actin; in addition, 2F7 IgM lambda immunoprecipitated recombinant human immunodeficiency virus type 1 (HIV-1) gp 160. 2F7 IgM lambda did not react with other autoantigens (double-stranded and single-stranded DNA, actin, bovine serum albumin, IgG), whereas 10C9 IgM kappa reacted with human IgG. The 2F7 IgM heavy-chain variable region (VH) showed a 95% nucleotide homology with a previously sequenced VHIII germline gene, hv3019b9, whereas the 10C9 IgM VH showed a 95% homology with a previously sequenced VHIV germline gene, VH4.21. Use of minimally modified VH genes and demonstration of reactivity with chronically present antigens (ie, actin, HIV-1 gp 160, or human IgG) suggests that B cells in HIV-1-infected individuals proliferating in response to chronic antigenic stimulation may be at increased risk for lymphomagenesis. 相似文献
68.
Alfredo Nunes Ferreira-Neto Tania Rodriguez-Gabella Leonardo Guimaraes Afonso Freitas-Ferraz Mathieu Bernier Camila Figueiredo Guimaraes Sergio Pasian Jean-Michel Paradis Robert Delarochellière Eric Dumont Siamak Mohammadi Dimitri Kalavrouziotis Mélanie Côté Philippe Pibarot Josep Rodés-Cabau 《Revista espa?ola de cardiología》2021,74(3):247-256
Introduction and objectivesWe assessed the long-term hemodynamic performance of transcatheter heart valve (THV) by paired transthoracic echocardiography (TTE), and the incidence, characteristics and factors associated with THV structural valve degeneration (SVD).MethodsA total of 212 patients who underwent transcatheter aortic valve replacement and had a potential follow-up > 5 years with at least 1 TTE ≥ 1-year postprocedure were included. All patients had a TTE at 1 to 5 years and 36 had another one at 6 to 10 years. SVD was defined as subclinical (increase > 10 mmHg in mean transvalvular gradient + decrease > 0.3 cm2 in valve area and/or new-onset mild or moderate aortic regurgitation) and clinically relevant (increase > 20 mmHg in mean transvalvular gradient + decrease > 0.6 cm2 in valve area and/or new-onset moderate-to-severe aortic regurgitation). Fifteen patients had a transesophageal echocardiography at the time of SVD diagnosis, and 85 an opportunistic computed tomography examination at 1 (0.5-2) years.ResultsTransvalvular mean gradient increased and valve area decreased over time (P < .01). At 8 years of follow-up, SVD occurred in 30.2% of patients (clinically relevant: 9.3%). Transesophageal echocardiography revealed thickened and reduced-mobility leaflets in 80% and 73% of SVD cases, respectively. No baseline or procedural factors were associated with SVD. THV underexpansion (3.5%) or eccentricity (8.2%) had no impact on valve hemodynamics/SVD at follow-up.ConclusionsA gradual THV hemodynamic deterioration occurred throughout a 10-year period, leading to SVD in ~30% of patients (clinically relevant in < 10%). Leaflet morphology/mobility were frequently impaired in SVD cases, but THV geometry did not influence valve hemodynamics or SVD. 相似文献
69.
Débora Nunes Mario Josep Guarro Janio Morais Santurio Sydney Hartz Alves Javier Capilla 《Antimicrobial agents and chemotherapy》2015,59(8):5018-5021
We evaluated the combination of posaconazole with amphotericin B in vitro and in a murine model of systemic infections caused by Sporothrix brasiliensis and Sporothrix schenckii
sensu stricto. In vitro data demonstrated a synergistic effect, and although posaconazole alone was effective against sporotrichosis, efficacy in terms of survival and burden reduction was increased with the combination. This combination might be an option against disseminated sporotrichosis, especially when itraconazole or amphotericin B at optimal doses are contraindicated. 相似文献
70.
Asymptomatic Floor‐of‐Mouth Mass in a 79‐Year‐Old Woman Misinterpreted As a Sublingual Gland Mucous Extravasation Cyst 下载免费PDF全文
Karuza Maria Alves Pereira DDS PhD Thâmara Manoela Marinho Bezerra DDS Filipe Nobre Chaves DDS MSc Francisco Samuel Rodrigues Carvalho DDS Sthefane Gomes Feitosa DDS Assis Filipe Medeiros Albuquerque DDS Ana Paula Negreiros Nunes Alves DDS PhD Fábio Wildson Gurgel Costa DDS PhD 《Journal of the American Geriatrics Society》2015,63(8):1705-1706