Local Disodium Cromoglycate Is Ineffective in Ulcerative Proctosigmoiditis

ABSTRACT. Conflicting results have emerged from studies using oral and rectal disodium cromoglycate (DSCG) in inflammatory bowel disease. In the present double-blind study, 43 patients with active ulcerative proctosigmoiditis received either placebo (n=22) or 600 mg DSCG (n= 21) rectally as enemas for eight weeks. Assessment was made from clinical investigations, endoscopy, laboratory tests, biopsies, and diary cards. No statistically significant differences in bowel frequency, rectal bleeding, general well-being, abdominal pain, and severity and extent of the disease were found between the groups during the study. There was no significant change in the histologic parameters. No side-effect was encountered. It is concluded that DSCG did not improve symptoms or inflammatory changes in ulcerative proctosigmoiditis.     

An evaluation of the duration and the results of orthodontic treatment

abstract – In 1,486 schoolchildren with various anomalies, different needs of orthodontic treatment, and treated with different techniques, the following variables were studied: uncompleted orthodontic treatment and reason for cessation of treatment, duration of active treatment, duration of retention period, complete registration period, results of treatment. One to five years after the end of treatment, 300 cases were examined regarding relapse, opinion of treatment, and opinion of the results of treatment.     

Orthodontic need of treatment of Swedish schoolchildren from objective and subjective aspects

abstract – Of 5,459 schoolchildren in the town of Umeå, Sweden 26.2 % were regarded as not being in need of orthodontic treatment. As judged according to a four-grade scale the need was objectively little in 29.4 % of the children, moderate in 33.6 % and strong for 10.8 %. Of the children with objective need of treatment, 21.2 % were not interested in orthodontic treatment. In 939 children referred from the district of Västerbotten the need of treatment was little in only 3.2 %, while strong in 52.3 %, and very strong in 6.3 %. Only 47.8 % of the children were interested in orthodontic treatment.     

Pulmonary Function in Patients with Endobronchial Sarcoidosis

ABSTRACT Sixty-four patients with clinically, radiologically and histopathologically established sarcoidosis were studied by bronchoscopy and static and dynamic spirometry. Sarcoid bronchostenosis was established by bronchoscopy in nine patients. Twenty-one had bronchial sarcoidosis without stenosis and 34 had no evidence of bronchial sarcoidosis. Patients with sarcoid bronchostenosis showed a marked impairment of lung function, mostly with an obstructive pattern. There was no improvement in lung function after bronchodilatation in these patients. Obstructive spirometry pattern was also found in three patients with bronchial sarcoidosis stage II without stenosis. None of the patients without bronchial sarcoidosis had an obstructive pattern. All six patients with restrictive spirometry pattern in the two groups without bronchostenosis had stage II sarcoidosis. At follow-up, lung function had improved in five patients, four with sarcoid bronchostenosis and one patient with stage II without bronchial sarcoidosis. Four of these patients were treated with oral corticosteroids. When clinical signs of airway obstruction are present in patients with sarcoidosis, bronchial sarcoidosis with or without bronchostenosis should be suspected. When bronchial sarcoidosis is present, oral corticosteroid treatment should be tried.     

Di Guglielmo's Disease Comments on a Case of Erythroleucemic Myelosis

Summary
A disease is described in a girl aged 14 years, in which an acute myeloblasts leu-cemia was combined with a probably analogous affection of the erythropoietic system. There were definitely leucemic myeloblast counts in the blood, but there, as well as in the bone marrow, the myeloblasts were outnumbered by mostly very immature erythroblasts, many of which were atypical. A hyperchromic anemia and signs of hemorrhagic diathesis were present. The clinical course of the disease was that of a very acute leucemia and the patient died after three weeks' observation. It is considered to be a case of genuine erythroleucemic myelosis (erythroleucemia).