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941.
It is well known that rifampicin can cause nephrotoxicity. Rifampicin-related pancreatitis and hyperthyroidism are rarely
reported in the same patient in the presence of tubulointerstitial nephritis. Reported herein is the medical management of
a patient with hemolytic anemia, acute renal failure, pancreatitis, and hyperthyroidism during with rifampicin therapy. A
50-year-old man was admitted to the hospital owing to abdominal colic and acute renal failure. He was treated with 2 courses
of tetracycline-rifampicin for brucellosis 3 weeks and 4 months prior to admission. Physical examination showed blood pressure
of 130/70 mm Hg, pulmonary crackles, and edema. Laboratory findings are detailed in the case report. Findings of abdominal
ultrasonography suggested edematose pancreatitis and thyroid ultrasonography showed several solid nodules. Renal biopsy showed
tubu-lointerstitial nephritis. Although rifampicin-related tubulointerstitial nephritis and acute renal failure are not uncommon
during rifampicin therapy, the convergence of hyperthyroidism, pancreatitis, tubulointerstitial nephritis, and acute renal
failure rarely presents in the same patient. Although pancreatitis, tubulointerstitial nephritis, and acute renal failure
were ameliorated with corticoid therapy within 2 months, hyperthyroidism continued and required antithyroid therapy. In conclusion,
rifampicin may trigger hyperthyroidism in patients with goiter. 相似文献
942.
Cüneyt Turan Ahmet Tutuş Meral Tayan Ercan Bülent Hayri Özokutan Tacettin Yolcu Özkan Köse Mustafa Küçükaydın 《Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie》1997,197(3):157-164
An experimental study was planned to evaluate 99mTc-citrate, 67Gacitrate and 99mTc(V) dimercaptosuccinic acid (DMSA) as agents for the visualization of acute appendicitis. Appendiceal ligation was performed through a midline incision in 24 rabbits. Twenty-four hours later the animals were divided into three equal groups. The rabbits were injected through the aurical vein with 1 mCi (37 MBq) 99mTc-citrate in group I, 0.5 mCi (18.5 MBq) 67Ga-citrate in group II and 1 mCi (37 MBq) 99mTc(V) DMSA in group III. After 3 h, static images of the rabbits were obtained with a gamma camera. There were positive images in seven, six and five rabbits in groups I, II and III respectively. The image quality was better in group I than in the other groups. Also, the mean uptake in group I was significantly higher than those of other two groups (P < 0.05). There was no significant difference between groups II and III (P > 0.05). All rabbits had appendicitis confirmed histologically. In conclusion, these results show that 99mTc-citrate is preferable to 67Ga-citrate and 99mTc(V) DMSA for the differential diagnosis of acute abdominal inflammations such as appendicitis, because of higher concentration ratios, simple and rapid preparation, low cost, excretion mainly through the kidneys and fast blood clearance. 相似文献
943.
Uzun M Baysan O Erinc K Ozkan M Sag C Genc C Karaeren H Yokusoglu M Isik E 《The international journal of cardiovascular imaging》2005,21(6):633-640
Background
Angle-correction is an important limiting factor for using proximal isovelocity surface area (PISA) method in measuring mitral
valve area (MVA). In this study, we derived a novel formula, which simplifies the angle-correction, and tested its use in
patients with mitral stenosis (MS). MethodsThe study included 30 MS patients without concomitant aortic or mitral regurgitation. We used mathematical equations and established
a relation between the angle and its corresponding border, ‘a’, by using linear regression analysis. It was found that MVA is equal to [(1.11*a2 + 0.95)* r2 (Val/Vmax)]. We compared this formula with plain angle-corrected and solid angle-corrected PISA methods, planimetry (reference method)
and pressure-half time method by linear regression analysis. Results All methods were in significant relation with the reference method, two-dimensional planimetry. We found that there is a
good relation between our method and planimetry (r = 0.79, p < 0.001), pressure half-time method (r = 0.85, p < 0.001), angle-corrected PISA method (r = 0.99, p < 0.001), and solid angle-corrected PISA method (r = 0.88, p < 0.001). The time duration of the new method was shorter (p < 0.001). ConclusionOur method is an easy way for applying angle-corrected PISA method to mitral valve area measurement in patients with mitral
stenosis. Absence of the need for estimating the angle is the major advantage. 相似文献
944.
Nordmann Patrice Sadek Mustafa Poirel Laurent Chakraborty Trinad 《European journal of clinical microbiology & infectious diseases》2022,41(4):689-690
European Journal of Clinical Microbiology & Infectious Diseases - 相似文献
945.
946.
Bayram I Ibiloğlu I Uğraş S Yilmaz N Harman M 《The Tohoku journal of experimental medicine》2004,204(4):317-322
Medulloblastoma is a malignant invasive embryonal tumor of the cerebellum with preferential manifestation in children. The peak of occurrence is seven years of age. Seventy percent of medulloblastomas occur in individuals younger than 16. In adulthood, 80% of medulloblastomas arise in the 21-40 years age group. A 48-year-old male patient was admitted to the hospital with complains of headache, ataxia, morning vomiting and difficulty in speech was operated with the diagnosis of presence of mass of 4 x 7 cm size retaining a diffuse homogenous contrast in the posterior fossa. The diagnosis of desmoplastic medulloblastoma was given after histopathological examination. Immunohistochemical examination revealed that neoplastic cells showed staining with neuron-specific enolase and synaptophysin but not with glial fibrillary acidic protein. This lesion showed nodular, reticulin free-zones (pale islands) surrounded by densely packed, highly proliferative cells. The pale regions within the tumor did not contain reticulin fibers. Desmoplastic medulloblastoma is encountered especially in adulthood. This type of tumor rarely occurs beyond the fifth decade of life. We present a case of desmoplastic medulloblastoma in a 48-year-old male. 相似文献
947.
Gullu H Caliskan M Erdogan D Yilmaz S Dursun R Ciftci O Topcu S Yucel E Muderrisoglu H 《Annals of medicine》2007,39(2):154-159
BACKGROUND: Behcet's disease (BD) is characterized with remissions and exacerbations. However, to date, there is no study to investigate a possible association of disease activity (active versus inactive disease period) with cardiovascular complications. METHODS: Forty patients with BD were evaluated in both active and in inactive disease period. For the control group 45 healthy volunteers, age and sex matched, were registered. Subjects with at least a 15-day lesion-free period were regarded in inactive disease period, and subjects with any oral, skin, and/or genital lesion was regarded as in active disease period. In each subject coronary diastolic peak flow velocities (DPFV) were measured at baseline and after dipyridamole infusion (0.84 mg/kg over 6 minutes) using an Acuson Sequoia C256 echocardiography system. Coronary flow reserve (CFR) was defined as the ratio of hyperemic to baseline DPFV. RESULTS: CFR values were significantly lower in BD patients compared to the controls (2.57+/-0.50 versus 2.87+/-0.53, P = 0.006). In active disease period, basal DPFV (24.6+/-7.5 versus 27.3+/-6.6, P = 0.019) was significantly higher than in the inactive disease period. In the active disease period hyperemic DPFV (61.7+/-14.9 versus 56.8+/-16.7, P = 0.015) values decreased significantly. Therefore, in the active disease period CFR significantly decreased from 2.57+/-0.50 to 2.09+/-0.46, P<0.001. The only independent predictor of CFR within the active disease period was the disease duration (beta = -0.384, P = 0.012). CONCLUSION: Within the active disease period, coronary microvascular function is more prominently impaired in BD patients. Therefore, BD patients are possibly more vulnerable to cardiovascular manifestations when they are in an active disease period. 相似文献
948.
Unalacak M Aydin M Ermis B Ozeren A Sogut A Demirel F Unluoglu I 《The Tohoku journal of experimental medicine》2004,204(1):63-69
The pathogenesis of monosymptomatic nocturnal enuresis is controversial. Various urodynamic studies showed bladder hyperactivity in enuretic children. But the exact cause is not precisely known. The aim of this study was to understand whether the autonomic nervous system dysfunction is involved in this bladder hyperactivity or not. Heart rate variability measurement is widely used for evaluation of cardiac autonomic activity. We evaluated cardiac autonomic nervous system functions in monosymptomatic nocturnal enuretic children by using 24-hour Holter electrocardiogram. The study group consisted of 32 enuretic children (20 boys and 12 girls) and the control group consisted of 20 healthy children (12 boys and 8 girls). In these two groups, we assessed cardiac autonomic regulation by analysis of heart rate variability, and found a significantly higher parasympathetic activity in enuretic children than controls. We suggest that the parasympathetic nervous system hyperactivity plays a role in nocturnal enuresis by causing vesical hyperactivity in monosymptomatic enuretic children. 相似文献
949.
Eda Suer Suha Sayrac Elif Sarinay Hakan Emre Ozturk Mustafa Turkoz Akitoyo Ichinose Tsuyoshi Nagatake Kamruddin Ahmed 《Journal of infection and chemotherapy》2008,14(4):333-336
S-carboxymethylcysteine (S-CMC) is a mucolytic agent that can prevent respiratory infection by decreasing the attachment of respiratory pathogens to human pharyngeal epithelial cells (HPECs). Streptococcus pneumoniae is a major cause of respiratory infections. A previous study revealed that treatment of S. pneumoniae with S-CMC caused a decrease in the attachment of this bacterium to HPECs. In the present study we found that the effect of S-CMC varied according to hosts and strains. S-CMC treatment altered the surface structure of S. pneumoniae, resulting in a decrease of attachment, without affecting the virulence of the bacteria. 相似文献
950.
Burhan Özalp Ömer Berköz Mustafa Aydınol 《Journal of plastic surgery and hand surgery》2018,52(1):7-13
Objective: The aim of this study was to assess the efficacy of suction-assisted liposuction (SAL) in Simon grade 2b gynecomastia and its effect on sternal notch to nipple areola (SNN) distance.Methods: A retrospective analysis was performed on 21 patients with grade 2b gynecomastia who underwent SAL. Preoperative and postoperative SNN distances of the patients were measured, the results were analysed using a Mann–Whitney U test and a p-value <.05 was accepted as statistically significant. Aesthetic results were evaluated by the surgical team considering five criteria: breast size, breast shape, nipple-areolar complex positioning, scarring, and skin tightness of the breast envelope. A 10-point Likert scale was used to assess patient satisfaction with SAL surgery.Results: All of the patients were followed up for an average period of 17.8 months (range?=?12–28 months). The mean amount of lipoaspirate was 232?mL per breast (range?=?190–310?mL). The mean preoperative SNN distance was 22.3?cm (range?=?20–23.5?cm), whereas postoperative was 21.3?cm (range?=?19.2–22.8?cm); the difference was statistically significant (p?.05). There was one case of nipple areola necrosis, three hypoesthesia, five persistent pains, and four slight buttonhole deformities. The aesthetic result was evaluated as very good by the surgical team, and the overall patient satisfaction rate in terms of breast shape and volume was 92%.Conclusions: It was concluded that SAL provides a good aesthetic outcome in patients with Simon grade 2b gynecomastia and shortens the SNN distance by 1?cm, but further clinical studies are required to support this conclusion. 相似文献