全文获取类型
收费全文 | 62600篇 |
免费 | 6231篇 |
国内免费 | 4421篇 |
专业分类
耳鼻咽喉 | 555篇 |
儿科学 | 778篇 |
妇产科学 | 561篇 |
基础医学 | 6232篇 |
口腔科学 | 1026篇 |
临床医学 | 7249篇 |
内科学 | 8311篇 |
皮肤病学 | 633篇 |
神经病学 | 3056篇 |
特种医学 | 2372篇 |
外国民族医学 | 24篇 |
外科学 | 6900篇 |
综合类 | 13393篇 |
现状与发展 | 18篇 |
一般理论 | 1篇 |
预防医学 | 4808篇 |
眼科学 | 1253篇 |
药学 | 6782篇 |
63篇 | |
中国医学 | 4552篇 |
肿瘤学 | 4685篇 |
出版年
2024年 | 201篇 |
2023年 | 804篇 |
2022年 | 1861篇 |
2021年 | 2637篇 |
2020年 | 2205篇 |
2019年 | 1768篇 |
2018年 | 1843篇 |
2017年 | 1921篇 |
2016年 | 1834篇 |
2015年 | 2664篇 |
2014年 | 3353篇 |
2013年 | 3533篇 |
2012年 | 4961篇 |
2011年 | 5534篇 |
2010年 | 4252篇 |
2009年 | 3646篇 |
2008年 | 4098篇 |
2007年 | 3952篇 |
2006年 | 3746篇 |
2005年 | 3268篇 |
2004年 | 2665篇 |
2003年 | 2589篇 |
2002年 | 2296篇 |
2001年 | 1699篇 |
2000年 | 1284篇 |
1999年 | 975篇 |
1998年 | 591篇 |
1997年 | 575篇 |
1996年 | 446篇 |
1995年 | 386篇 |
1994年 | 332篇 |
1993年 | 200篇 |
1992年 | 181篇 |
1991年 | 199篇 |
1990年 | 152篇 |
1989年 | 126篇 |
1988年 | 98篇 |
1987年 | 78篇 |
1986年 | 84篇 |
1985年 | 57篇 |
1984年 | 36篇 |
1983年 | 18篇 |
1982年 | 14篇 |
1981年 | 7篇 |
1980年 | 11篇 |
1979年 | 9篇 |
1977年 | 7篇 |
1976年 | 12篇 |
1975年 | 6篇 |
1974年 | 8篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
61.
Objective: Severe scoliosis refers to scoliosis with serious and stiff curve. It always combins with trunk imbalance in coronal and sagittal contour. Besides complex pathological changes, cardiopulmonary deficits and other concomitant diseases increase treatmental difficulties. So the treatment of severe scoliosis is always a great challenge to spine surgeon. Methods :Thirty-six patients with severe scoliosis received one stage posterior correction followed by anterior release during July 1997 to January 2003, including 9 males and 27 females. Mean age was 17.2 years. Of them, 33 was idiopathic scoliosis and 3 was neurofibromatosis scoliosis( Cobb angle: 85-116 degree); 20 cases were abnormal in sagital plane. Three-dimensional devised instrumentation were applied such as CD, CD-Horizon, TSRH or Isola in posterior procedure followed by anterior release during the same anesthesia. 31 cases of this group received thorac icplasty. Results: The correction in the frontal plane achieved an average of 48.5%. In the sagittal plane, the pathological shape of the spine was reduced and distinctly ameliorated. 80. 6% of the patients maintained or achieved balance of sagittal plane. There were no complications of severe neurological deficit, hook displacement, rod broken, and deep infection at follow-up. One case occurred traumatic pleurisy after operation and another appeared pseudarthrosis 2 years later. One case demonstrated imbalance 11 months after operation. One patient was presented loss of correction more than 10 degree at one year follow-up and 5.2 degree in average. Conclusion:The study indicates that the one stage posterior correction combined with anterior release in treatment of severe scoliosis can achieve satisfactory correction. Appropriate choice of cases, preoperational detailed assessment and application of SEP and wake-up test during operation can possibly reduce severe complication. The long-term outcomes still need further observation. 相似文献
62.
63.
64.
静脉预注H1,H2受体阻滞药对减轻鱼精蛋白副作用的研究 总被引:3,自引:0,他引:3
将30例ASD、VSD患者随机分为对照与预防用药两组,对比观察H1、H2受体阻滞药苯海拉明、西米替丁对减轻鱼精蛋白副作用的效果和应用鱼精蛋白后补体C3、C4、CH50浓度变化。结果发现预防用药组血液动力学变化明显小于对照组,两组之间差异显著(P<0.01)。应用鱼精蛋白后C3、C4、CH50均下降,与用药前相比差异显著(P<0.01)。提示鱼精蛋白中和肝素可引起补体激活、组胺释放,H1、H2受体阻滞药能够减轻鱼精蛋白引起的血压下降。 相似文献
65.
Structural vertebral changes in the horizontal plane in idiopathic scoliosis and the long-term corrective effect of spine instrumentation 总被引:1,自引:0,他引:1
Summary The rotation and structural changes of the apex vertebra in the horizontal plane as well as of the thoracic cage deformity were quantified by measurements on computed tomography (CT) scans from patients with right convex thoracic idiopathic scoliosis (IS). The CT scans were obtained from 12 patients with moderate scoliosis (mean Cobb angle 25.8°, r 13°–30°) and from 33 with severe scoliosis (mean Cobb angle 46.2°, r 35°–71°). In addition, CT scans of thoracic vertebrae from 15 patients without scoliosis were used as reference material. Ten of the scoliotic cases had had Cotrel-Dubousset instrumentation (CDI) and posterior fusion and had entered a longitudinal study on the effect of operative correction on the re-modelling of the apical vertebra. An increasingly asymmetrical vertebral body, transverse process angle, pedicle width and canal width were found in the groups with scoliosis as compared with the reference material. Vertebral rotation and rib hump index were significantly larger in patients with early and advanced scoliosis than in normal subjects. The modelling angle of the vertebral body, the transverse process angle index and the vertebral rotation in relation to the middle axis of the thoracic cage were significantly greater in patients with severe than with moderate scoliosis. The results of this longitudinal study suggest that the structural changes of the apical vertebra regress 2 years or more after CD instrumentation. 相似文献
66.
解磷注射液救治急性有机磷农药中毒34例临床报告 总被引:1,自引:0,他引:1
将急性有机磷农药中毒患者69例随机分为2组,一组主要应用解磷注射液治疗(新疗法34例),另一组(35例)主要应用阿托品治疗。两组治愈率分别为97.1%及77.1%,疗效比较差异显著(P<0.05)。新疗法的优点是起效快,作用持久,疗程短(两组比较P<0.001),副反应轻,值得推广应用。并就应用方法及注意事项等作了探讨,也强调了早期足量用药的重要性。 相似文献
67.
安吉复口服液的耐缺氧,耐低温和抗疲劳作用 总被引:2,自引:0,他引:2
采用缺氧、寒冷和负重游泳等方法,观察了安吉复口服液(0.025、0.1和0.4mg·kg~(-1),ig,qd×14d)对小鼠的耐缺氧、耐低温及抗疲劳作用.结果表明,安吉复口服液0.1、0.4mg·kg~(-1)可延长KCN中毒小鼠的存活时间及延长小鼠在寒冷环境中存活时间,而0.4mg·kg~(-1)可延长常压缺氧条件下小鼠存活时间及延长小鼠负重游泳时间. 相似文献
68.
核素显像对小儿消化道出血的病因诊断 总被引:5,自引:0,他引:5
目的探讨核素显像对小儿消化道出血,特别是对Meckel憩室、肠重复畸形的病因诊断的价值。方法对26例腹痛、便血为主要症状的患儿行99m锝酸盐(99mTcO-4)显像,其中12例显像阴性者于检查后24小时有活动性出血者,再行99m锝标记红细胞显像。所有病例的诊断均经手术、病理及内窥镜等检查所证实。结果99mTcO-4显像诊断Meckel憩室和肠重复畸形的敏感性、特异性、准确性分别为85.7%(12/14)、91.7%(11/12)及88.5%(23/26)。结论核素显像具有无创、方法简单易行等特点,特别是对异位胃粘膜诊断具有较好的灵敏性和特异性。核素显像可作为下消化道出血病因诊断的有效方法。 相似文献
69.
急性脑梗塞患者血清肿瘤坏死因子水平变化的观察 总被引:7,自引:0,他引:7
采用双抗体夹心ELISA法对30例正常对照和36例急性脑梗塞患者血清肿瘤坏死因子(TNF)水平进行了检测。结果显示:急性脑梗塞组血清TNF水平显著高于正常对照组,血清TNF水平变化与脑梗塞容积大小密切相关,恢复期血清TNF水平显著降低。结果提示,TNF参与了脑梗塞发生后病理变化过程,检测血清TNF对判定脑梗塞容积大小有一定的临床意义。 相似文献
70.
J A Temlett A Ming M Saling V U Fritz A Blumenfeld T R Bilchik A L Becker P B Fourie H E Reef 《Suid-Afrikaanse tydskrif vir geneeskunde》1990,78(11):680-685
Patients with moderately severe Parkinson's disease complicated by the adverse effects of chronic levodopa use benefited from the addition of bromocriptine (Parlodel; Sandoz) in doses up to 26 mg daily, which allowed an approximate 30% reduction of levodopa dose. This resulted in a significant decrease in the amount of levodopa side-effects while maintaining or improving the original parkinsonian clinical stage. Increased effectiveness in these patients was not associated with increased dosage beyond 25-30 mg daily. When the doses of bromocriptine were increased slowly, the adverse reactions were minor and usually transient. 相似文献