全文获取类型
收费全文 | 1645篇 |
免费 | 87篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 45篇 |
妇产科学 | 47篇 |
基础医学 | 240篇 |
口腔科学 | 69篇 |
临床医学 | 145篇 |
内科学 | 316篇 |
皮肤病学 | 11篇 |
神经病学 | 107篇 |
特种医学 | 37篇 |
外科学 | 103篇 |
综合类 | 15篇 |
一般理论 | 4篇 |
预防医学 | 180篇 |
眼科学 | 212篇 |
药学 | 75篇 |
中国医学 | 6篇 |
肿瘤学 | 114篇 |
出版年
2023年 | 17篇 |
2022年 | 23篇 |
2021年 | 50篇 |
2020年 | 31篇 |
2019年 | 37篇 |
2018年 | 40篇 |
2017年 | 26篇 |
2016年 | 41篇 |
2015年 | 48篇 |
2014年 | 54篇 |
2013年 | 59篇 |
2012年 | 94篇 |
2011年 | 91篇 |
2010年 | 44篇 |
2009年 | 48篇 |
2008年 | 87篇 |
2007年 | 86篇 |
2006年 | 93篇 |
2005年 | 69篇 |
2004年 | 54篇 |
2003年 | 55篇 |
2002年 | 37篇 |
2001年 | 28篇 |
2000年 | 34篇 |
1999年 | 30篇 |
1998年 | 8篇 |
1997年 | 10篇 |
1996年 | 6篇 |
1995年 | 9篇 |
1993年 | 14篇 |
1992年 | 32篇 |
1991年 | 36篇 |
1990年 | 26篇 |
1989年 | 28篇 |
1988年 | 31篇 |
1987年 | 23篇 |
1986年 | 32篇 |
1985年 | 26篇 |
1984年 | 32篇 |
1983年 | 22篇 |
1982年 | 13篇 |
1981年 | 8篇 |
1980年 | 10篇 |
1979年 | 13篇 |
1978年 | 11篇 |
1977年 | 12篇 |
1976年 | 8篇 |
1974年 | 5篇 |
1973年 | 7篇 |
1970年 | 5篇 |
排序方式: 共有1732条查询结果,搜索用时 15 毫秒
31.
32.
Michels R Hoffmann H Windeler J Barth H Hopkins G 《Journal of thrombosis and thrombolysis》1995,2(2):117-124
Background: Urokinase or two-chain urokinasetype plasminogen activator has been shown to be effective in the treatment of acute myocardial infarction. Its parent molecule, single-chain urokinase-type plasminogen activator (scu-PA), unlike urokinase, can selectively activate fibrinbound plasminogen. The induced clot lysis is amplified by plasmin-triggered conversion of scu-PA to urokinase and by further plasmin generation. The aim of our study was to compare the efficacy and safety of recombinant unglycosylated scu-PA, or saruplase, and urokinase at doses considered optimal in patients with acute myocardial infarction within 6 hours of onset of pain. Methods and results: In a double-blind trial 543 patients were randomized to saruplase (20 mg bolus + 60 mg/hr) or urokinase (1.5 million unit bolus + 1.5 million units/hr). Primary endpoint: The patency rates at 24–72 hours were 75.4% (95% CI 70.3–80.5%) for saruplase and 74.2% (95% CI 69.0–79.4%;P=0.77) for urokinase. Secondary endpoint: The incidence of bleeding events in both groups was 10.7%. There were three hemorrhagic strokes in the saruplase group (ns). Other efficacy and safety evaluations: Apart from the generation of more fibrinogen degradation products under saruplase, the changes in hemostatic parameters did not differ. Hospital mortality was 4.4% for saruplase and 8.1% for urokinase. This nonsignificant difference was maintained for 1 year. Conclusion: The efficacy and safety of saruplase and urokinase in the regimens used are very similar. 相似文献
33.
Dr. R.M. Waeschle MaHM P. Michels M. Jipp S. Riech T. Schulze C.E. Schmidt M. Bauer 《Der Anaesthesist》2014,63(2):154-162
Background
The current situation in hospitals is characterized by financial limitations and simultaneously by increasing demands on quality and safety. The operative interface between anesthesia and transfusion medicine affects both factors.Aim
A detailed analysis was performed to evaluate the process quality at this operative interface at the University Hospital of Göttingen. The aim of the project was to revise und develop the structures and responsibilities at this interface, to dispose of weak points and to realize the optimization potential in the supply of blood products.Material and methods
A databank-based electronic data processing solution was established with the clear definition of responsibilities for the various workflow procedures and the written documentation of these definitions in standard operating protocols. In order to guarantee the necessary transparency a routine reporting system to the department of surgery was established. In addition, a continuous further development of the blood supply standard based on electronic report data was implemented.Results
By implementing the above named measures the rate of supplied to transfused blood products could be increased from 43.1?% to 55.7?%. The compliance with the blood supply standard improved continually over the first 18 months from 60.3?% to 92.3?%. The rate of supplied blood product deliveries without subsequent operation could be reduced from 9.0?% to 4.6??%. As a result of this optimization the supply costs in the internal cost allocation were reduced from 9,406 € to 3,544 €.Conclusion
The measures described are appropriate to cost-effectively improve quality and patient safety. The optimization measures presented in this article can be implemented in other hospitals to increase quality and safety after individual adjustment to the local circumstances. 相似文献34.
35.
36.
37.
Mariane G. Delaunay Carl Larsen Huw Lloyd Matthew Sullivan Robyn A. Grant 《Journal of anatomy》2020,237(2):355-366
Avian rictal bristles are present in many species of birds, especially in nocturnal species. Rictal bristles occur along the upper beak and are morphologically similar to mammalian whiskers. Mammalian whiskers are important tactile sensors, guiding locomotion, foraging and social interactions, and have a well-characterised anatomy. However, it is not yet known whether avian rictal bristles have a sensory function, and their morphology, anatomy and function have also not been described in many species. Our study compares bristle morphology, follicle anatomy and their association with foraging traits, across 12 Caprimulgiform species. Rictal bristle morphology and follicle anatomy were diverse across the 12 species. Nine of the 12 species had mechanoreceptors around their bristle follicles; however, there was large variation in their musculature, mechanoreceptor numbers and bristle morphology. Overall, species with short, thin, branching bristles that lacked mechanoreceptors tended to forage pre-dusk in open habitats, whereas species with mechanoreceptors around their bristle follicle tended to forage at night and in more closed habitats. We suggest that rictal bristles are likely to be tactile in many species and may aid in navigation, foraging and collision avoidance; however, identifying rictal bristle function is challenging and demands further investigation in many species. 相似文献
38.
39.
Noralane M. Lindor William A. Smithson Carlos A. Ahumada Virginia V. Michels John M. Opitz 《American journal of medical genetics. Part A》1995,56(1):10-11
We report on two father-son pairs with isolated nonsyndromal asplenia. This may represent autosomal dominant inheritance of a mutation in a gene involved with spleen development and determination of laterality. The incidence of hereditary isolated asplenia is unknown; therefore, screening for asplenia in first degree relatives of individuals with (poly)asplenia should be considered. © 1995 Wiley-Liss, Inc. 相似文献
40.
da Cunha Jaeger Mariane Ghisleni Eduarda Chiesa Cardoso Paula Schoproni Siniglaglia Marialva Falcon Tiago Brunetto André T. Brunetto Algemir L. de Farias Caroline Brunetto Taylor Michael D. Nör Carolina Ramaswamy Vijay Roesler Rafael 《Journal of molecular neuroscience : MN》2020,70(6):981-992
Journal of Molecular Neuroscience - Medulloblastoma (MB), which originates from embryonic neural stem cells (NSCs) or neural precursors in the developing cerebellum, is the most common malignant... 相似文献