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81.
Carlos Morales-Uribe Ana Ramírez Tatiana Suarez-Poveda Margarita Ortiz Alvaro Sanabria 《Emergency radiology》2016,23(5):421-431
This study was conducted in order to define the diagnostic performance of CT angiography for vascular injuries compared with angiography in patients with neck trauma. CT angiography is the cornerstone of diagnosis for hemodynamically stable patients with wounds suspicious of vascular trauma in the limbs, chest, or abdomen. Available evidence for the use of CT angiography in neck vascular trauma comes from small case series and few randomized controlled trials, and high-quality information does not exist regarding its performance. A protocol using the recommendations of the Cochrane Collaboration was designed. A systematic search of diagnostic studies without limits on language or time was carried out to December 2014. Studies including patients with neck trauma with retrospective or prospective data collection that assessed CT angiography compared with other methods were selected. Methodological quality was assessed using the QUADAS-2 tool. A hierarchical model ROC curve and a bivariate random effects model were used for the pooled analysis. Sixteen studies were selected and reviewed, and nine studies with 693 patients were included in this review. The overall sensitivity was 97 % (95 % CI 0.77–1.00; I 2?=?65.7 % (41.4–90.0)), while the overall specificity was 99 % (95 % CI 0.93–1.00; I 2?=?0). The hierarchic ROC curve showed an area under the curve of 0.99. Publication bias was not identified in this study. CT angiography can be stated as the gold standard for diagnosing vascular injuries in hemodynamically stable patients with neck trauma. 相似文献
82.
Margarita L. Martinez-Fierro Edwin A. Reyes-Oliva Griselda A. Cabral-Pacheco Idalia Garza-Veloz Maria C. Aceves-Medina Martha Luevano 《Hypertension in pregnancy》2016,35(2):189-201
Background: Inadequate trophoblast invasion and the subsequent inflammatory response have been implicated in preeclampsia (PE) pathogenesis. Because MYC-induced nuclear antigen (MINA) gene expression is involved in cell proliferation and differentiation, inflammatory response modulation, and the unpaired regulation of which is associated with human diseases, we sought to investigate the connection between MINA and PE.Objective: The aim of this study was to evaluate the possible relationship between the MINA rs4857304 variant and susceptibility to PE development as well as to estimate placental MINA gene expression and its association with PE.Methods: About 242 pregnant women (126 PE cases and 116 controls) were included. MINA genotyping and gene expression were evaluated by quantitative real-time polymerase chain reaction using TaqMan probes.Results: The G/G genotype of the MINA rs4857304 variant was associated with severe PE (p = 0.027, OR = 1.8, 95% CI = 1.8–3.2). Carriers of one G allele of the MINA rs4857304 variant exhibited a 1.7-fold increased risk of severe PE (p = 0.029, 95% CI = 1.1–3.0). MINA was underexpressed in preeclamptic placentas and MINA expression differed between the mild and severe PE groups. Differences in the expression levels of MINA were found among women with the T/T genotype of the rs4857304 polymorphism and carriers of at least one G allele (p = 0.024).Conclusion: PE and its severity are associated with the underexpression of placental MINA, and the G/G genotype of the MINA rs4857304 variant may modify the risk of severe PE among the PE cases evaluated. 相似文献
83.
Retrospective cohort study of prognostic factors in patients with oral cavity and oropharyngeal squamous cell carcinoma 下载免费PDF全文
84.
Effectiveness of honey on radiation‐induced oral mucositis,time to mucositis,weight loss,and treatment interruptions among patients with head and neck malignancies: A meta‐analysis and systematic review of literature 下载免费PDF全文
85.
Lorena S. Pacheco David A. Hernández-Ontiveros Esmeralda Iniguez-Stevens Stephanie Brodine Richard S. Garfein Margarita Santibañez Miguel A. Fraga 《BMC public health》2018,18(1):1397
Background
Diabetes is a leading cause of morbidity and mortality in Mexico and understudied among indigenous populations. This study aimed to determine the prevalence and identify correlates of Type 2 diabetes mellitus (Type 2 DM) and metabolic syndrome (MetS) in a rural, indigenous community in Northwestern Mexico.Methods
A cross-sectional study was conducted in the community of San Quintin, Baja California, Mexico, among a sample of households. A total of 275 participants (≥18?years old) underwent a questionnaire, physical examination, and serologic test. Prevalence and adjusted odds ratio (AOR), using logistic regression modeling, were estimated with 95% confidence intervals (95% CI).Results
The prevalence of Type 2 DM and MetS was 21.8 and 53.1%, respectively. Mean?±?standard deviation (SD) age and body mass index of study participants was 35.8?±?13.0?years and 28.7?±?5.6?kg/m2, respectively. Participants were 75% female and 60.7% self-identified as indigenous. Thirty-seven percent of adults had high blood pressure. After controlling for age, higher educational attainment had a protective effect on Type 2 DM (AOR?=?0.39; 95% CI 0.20, 0.77). Additionally, the presence of MetS was associated with being female (AOR?=?2.27; 95% CI 1.23, 4.14) and having lower educational attainment (AOR?=?0.62; 95% CI 0.37, 0.94).Conclusions
The prevalence of Type 2 DM and MetS was high in this rural and indigenous population, and education was shown to play a critical role. These findings support the need for community-inclusive health-promoting interventions in rural communities.86.
Short‐term effects of heat and cold on respiratory drug use. A time‐series epidemiological study in A Coruña,Spain 下载免费PDF全文
Dominic Royé Adolfo Figueiras Margarita Taracido 《Pharmacoepidemiology and drug safety》2018,27(6):638-644
The consumption of medication, especially over‐the‐counter drugs, can reflect environmental exposure with a lesser degree of severity in terms of morbidity. The non‐linear effects of maximum and minimum apparent temperature on respiratory drug sales in A Coruña from 2006 to 2010 were examined using a distributed lag nonlinear model. In particular, low apparent temperatures proved to be associated with increased sales of respiratory drugs. The strongest consistent risk estimates were found for minimum apparent temperatures in respiratory drug sales with an increase of 33.4% (95% CI, 12.5%‐58.0%) when the temperature changed from 2.8°C to ?1.4 °C. These findings may serve to guide the planning of public health interventions to predict and manage the health effects of exposure to the thermal environment for lower degrees of morbidity. More precisely, significant increases in the use of measured over‐the‐counter medication could be used to identify and anticipate influenza outbreaks due to a more sensitive degree of the data source. 相似文献
87.
On the use of the not‐at‐random fully conditional specification (NARFCS) procedure in practice 下载免费PDF全文
Daniel Mark Tompsett Finbarr Leacy Margarita Moreno‐Betancur Jon Heron Ian R. White 《Statistics in medicine》2018,37(15):2338-2353
The not‐at‐random fully conditional specification (NARFCS) procedure provides a flexible means for the imputation of multivariable missing data under missing‐not‐at‐random conditions. Recent work has outlined difficulties with eliciting the sensitivity parameters of the procedure from expert opinion due to their conditional nature. Failure to adequately account for this conditioning will generate imputations that are inconsistent with the assumptions of the user. In this paper, we clarify the importance of correct conditioning of NARFCS sensitivity parameters and develop procedures to calibrate these sensitivity parameters by relating them to more easily elicited quantities, in particular, the sensitivity parameters from simpler pattern mixture models. Additionally, we consider how to include the missingness indicators as part of the imputation models of NARFCS, recommending including all of them in each model as default practice. Algorithms are developed to perform the calibration procedure and demonstrated on data from the Avon Longitudinal Study of Parents and Children, as well as with simulation studies. 相似文献
88.
Vianna CB Gonzalez MM Dallan LA Shiozaki AA Medeiros FM Britto PC Cesar LA 《Resuscitation》2007,74(1):183-186
A previously asymptomatic 15-year-old boy was treated at our institution after an episode of chest pain, palpitation, and syncope while playing in a high school soccer game. The patient's resting electrocardiogram was normal. A transthoracic echocardiogram showed an anomalous left main coronary artery originating from the right sinus of Valsalva. Contrast-enhanced multidetector computed tomography demonstrated clearly that the anomalous vessel coursed between the aorta and the pulmonary trunk (interarterial subtype). Treadmill testing registered several nonsustained polymorphic ventricular tachycardias and transmural myocardial ischaemia in the early recovery phase (ST-elevation up to 5mm in CM5 and V2 leads). The patient underwent bypass grafting. One year later, he remains asymptomatic, and new treadmill tests have been normal. In this patient, severe transmural myocardial ischaemia was detected, possibly due to collapse or vasospasm of the anomalous vessel, triggering life-threatening ventricular arrhythmias. 相似文献
89.
Puriene A Janulyte V Musteikyte M Bendinskaite R 《Stomatologija / issued by public institution "Odontologijos studija" ... [et al.]》2007,9(1):10-20
The studies show a dental practitioner as a subject of a wide variety of physical and psychological ailments. It is induced or aggravated by the work specificity and greatly affects the health of dental professionals. Therefore, general health of dentists, especially effect of dental activity on it, is present-day, important and as a matter of fact not well documented subject. The aim of our review is to summarize and ascertain dental practice-related disorders influencing the physical and psychological health of practitioner. Also we would like to highlight the most vulnerable systems of the dental professional and to survey the best methods to overcome these ailments. RESULTS: There is growing body of evidence that suggests surprisingly high vulnerability within the dental profession to certain disorders and afflictions that can be categorized as practice-related. CONCLUSIONS: In different countries dentists reported having poor general health and suffer from various health-related problems. To enjoy and be satisfied with their professional and personal lives, dentists must be aware of the importance to maintain good physical and mental health. 相似文献
90.
We describe a patient with Hashimoto's encephalopathy presenting as long-standing episodes of aphasia associated with migraine-like headache. Repeated thyroid hormone levels were within normal values, but high titers of antithyroid antibodies in serum, and diffuse EEG slowing and CSF abnormalities during one episode led to the diagnosis. 相似文献