首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   33568篇
  免费   2306篇
  国内免费   167篇
耳鼻咽喉   427篇
儿科学   579篇
妇产科学   638篇
基础医学   3472篇
口腔科学   7544篇
临床医学   2061篇
内科学   7319篇
皮肤病学   764篇
神经病学   2090篇
特种医学   517篇
外科学   4822篇
综合类   174篇
一般理论   3篇
预防医学   2003篇
眼科学   450篇
药学   1470篇
中国医学   122篇
肿瘤学   1586篇
  2024年   119篇
  2023年   566篇
  2022年   450篇
  2021年   988篇
  2020年   555篇
  2019年   913篇
  2018年   1242篇
  2017年   889篇
  2016年   941篇
  2015年   1182篇
  2014年   1539篇
  2013年   1802篇
  2012年   2397篇
  2011年   2455篇
  2010年   1652篇
  2009年   1670篇
  2008年   2023篇
  2007年   2041篇
  2006年   1885篇
  2005年   1663篇
  2004年   1540篇
  2003年   1526篇
  2002年   1375篇
  2001年   341篇
  2000年   287篇
  1999年   338篇
  1998年   421篇
  1997年   349篇
  1996年   342篇
  1995年   299篇
  1994年   270篇
  1993年   209篇
  1992年   222篇
  1991年   140篇
  1990年   144篇
  1989年   93篇
  1988年   131篇
  1987年   112篇
  1986年   57篇
  1985年   103篇
  1984年   96篇
  1983年   99篇
  1982年   99篇
  1981年   78篇
  1980年   57篇
  1978年   35篇
  1977年   36篇
  1976年   28篇
  1975年   37篇
  1974年   33篇
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
51.
52.
Prospective evaluation of implants connected to teeth   总被引:1,自引:0,他引:1  
PURPOSE: This prospective clinical trial examined the effect on teeth and implants when rigidly or non-rigidly connected in a cross-arch model. MATERIALS AND METHODS: Thirty patients received 2 implants, 1 on each side of the mandible, and were restored with 3-unit fixed partial dentures connected either rigidly or non-rigidly to an abutment tooth. Patients were followed for at least 5 years post-restoration. RESULTS: Repeated-measures analysis revealed no significant difference in crestal bone loss at implants (rigid versus non-rigid methods). An overall significant difference (P < .001) was found comparing methods for teeth. Paired t tests revealed no significant differences in crestal bone levels for implants or teeth at the 5-year recall. Kaplan-Meier methods and the Cox proportional hazards model showed no differences between attachment methods with regard to success based on survival and bone loss criteria. During the 5-year recall period, 1 implant (rigid side) was removed. Four implants developed bone loss greater than 2 mm during the course of this trial. One tooth on the rigid side and 2 teeth on the non-rigid side had greater than 2 mm of crestal bone loss and were removed secondary to fractures. In all, 5 abutment teeth were removed, all of which had been treated with root canal therapy and fractured at the interface of the post within the tooth. There was no clear relationship of tooth fracture to attachment. Repeated-measures analysis of mobility values revealed no significant changes over the time course of this study, and paired t tests revealed no statistically significant differences between implants for mobility. Repeated-measures analysis and paired t tests for probing depth revealed no significant changes over the time course of this study. There were no significant differences in soft tissue indices for either attachment method. The percentage of patients who had measurable intrusion was 66% for the non-rigid group, and 44% for the rigid group; 25% of the non-rigid teeth had greater than 0.5 mm intrusion, compared with 12.5% for the rigid group. For the 2 time periods evaluated, there was no significant increase in intrusion over time. The non-rigid-side implant required more nonscheduled visits to treat problems than the rigid implant and the teeth. Discussion: Most patients were treated successfully with rigid or non-rigid attachment of implants to teeth. CONCLUSION: The high incidence of intrusion and non-scheduled patient visits suggest that alternative treatments without connecting implants to teeth may be indicated.  相似文献   
53.
The present investigation was designed to study the protective effect given by thyroid hormone (TH) on root resorption: (1) whether intra-peritoneal versus oral TH administration had the same efficiency; and (2) whether this effect involved local or systemic mechanisms. For this purpose, circulating T3 levels, systemic alkaline phosphatase (APase) activity, and 5'deiodinase (5'D) activity were evaluated in the periodontal area of 80 Sprague-Dawley rats, 8 weeks of age, in which orthodontic appliances had been inserted. The results showed that TH-treated animals (intra-peritoneal or oral) had significantly less force-induced root resorptive lesions compared with a control group, without apparent changes in T3 or APase levels, and that periodontal remodelling was accompanied by a significant increase in local T3 generation as a result of T4 deiodination. This 5'D activity was higher in those animals that received exogenous TH. These results suggest that this protective TH mechanism may be achieved at a local level and that administration of low doses of TH may play a protective role on the root surface either during orthodontic treatment or in those patients that present spontaneous root resorptive lesions.  相似文献   
54.
55.
The purpose of this study was to evaluate the effects of a change in the lateral anterior guidance pathway on the lateral border movement pathway of mandible. The results showed that altered occlusal guidance reproducibly and reversibly changed (increased) the lateral border movement area in two subjects who had unilaterally restricted lateral border movements.  相似文献   
56.
Implant-supported rehabilitation in the posterior maxillary region presents a series of challenges because of the possibility of increased pneumatization of the maxillary sinus after dental loss. In cases where significant maxillary bone resorption has occurred, efforts center on maximizing the use of the remaining bone to afford primary stability to the implants. This clinical report describes a patient with extreme maxillary atrophy for whom fixed rehabilitation supported on 8 implants was accomplished. A zygomatic implant, a pterygomaxillary implant, and 2 implants mesial and distal to both canine eminences were placed. This rehabilitation was accomplished with a less invasive technique and in a much shorter time period compared to a sinus lift procedure. One year after prosthetic loading, the clinical and radiological results remain satisfactory.  相似文献   
57.
Growth and development is the net result of environmental modulation of genetic inheritance. Mesenchymal cells differentiate into chondrogenic, osteogenic, and fibrogenic cells: the first 2 are chiefly responsible for endochondral ossification, and the last 2 for sutural growth. Cells are influenced by genes and environmental cues to migrate, proliferate, differentiate, and synthesize extracellular matrix in specific directions and magnitudes, ultimately resulting in macroscopic shapes such as the nose and the chin. Mechanical forces, the most studied environmental cues, readily modulate bone and cartilage growth. Recent experimental evidence demonstrates that cyclic forces evoke greater anabolic responses of not only craniofacial sutures, but also cranial base cartilage. Mechanical forces are transmitted as tissue-borne and cell-borne mechanical strain that in turn regulates gene expression, cell proliferation, differentiation, maturation, and matrix synthesis, the totality of which is growth and development. Thus, hereditary and mechanical modulations of growth and development share a common pathway via genes. Combined approaches using genetics, bioengineering, and quantitative biology are expected to bring new insight into growth and development, and might lead to innovative therapies for craniofacial skeletal dysplasia including malocclusion, dentofacial deformities, and craniofacial anomalies such as cleft palate and craniosynostosis, as well as disorders associated with the temporomandibular joint.  相似文献   
58.
59.
60.
In 1977, a survey of American and Canadian dental schools was conducted by Weintraub to determine the delegation of laboratory procedures in preclinical and clinical complete and removable partial denture programs. This was performed in light of challenges raised to the value of requiring dental students, rather than laboratory technicians, to perform the various laboratory procedures involved in the fabrication of complete and removable partial dentures. Since 1977, the rate of edentulism has declined in the United States, and fewer edentulous patients have sought regular dental care. In addition, approximately 20% fewer curriculum hours have been spent in dental schools in removable prosthodontic instruction; a declining number of graduating dental students have felt comfortable with their level of knowledge of removable prosthodontics, especially complete dentures, and have performed fewer removable prosthodontic procedures in practice because of a perceived lack of treatment cost-effectiveness. The present study, an 18-year follow-up to the 1977 survey, was designed to determine if such trends toward a deemphasis on removable prosthodontic treatment have affected the mechanisms of instruction in and the extent to which dental schools instruct students about removable-prosthodontics laboratory procedures. The 1995 survey was mailed to 53 American dental schools. Forty-six schools returned the completed survey, for a response rate of 87%. Results showed that the relative amount of material presented to students in clinical removable prosthodontics programs increased, primarily through the enhancement of laboratory technician support, both in-house and commercial, of student clinical removable prosthodontic laboratory procedures. The increase was greater than in preclinical removable prosthodontic programs, which were described in a companion article. The conflict between these outcomes and the call by the dental community, as well as that of the 1995 Institute of Medicine Study, for a reduced emphasis on teaching students about the technical details involved in removable prosthesis fabrication is recognized and explored.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号