Development of pre and post-operative models to predict early recurrence of hepatocellular carcinoma after surgical resection

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老年特发性便秘直肠肛门压力测试59例分析

目的　探讨老年慢性特发性便秘 (CIC)患者直肠肛门运动功能变化 ,　 方法 　采用瑞典Medtronic公司生产的 8通道水灌注式消化道压力检测系统对 5 9例老年CIC患者及 36例老年对照者进行直肠肛门压力测定。　 结果 　老年CIC患者最大缩榨压、模拟排便时肛管压力变化低于老年对照组 (P <0 0 5 ) ,直肠初始感觉阈值、排便阈值和最大耐受容量均高于老年对照组 (P <0 0 5 ) ,2 8例 (47 5 % )老年CIC患者模拟排便时出现肛管压力异常升高。　 结论 　老年CIC与直肠低敏感、高耐受及排便时直肠肛管运动不协调有关     

干细胞治疗缺血性心力衰竭研究进展

干细胞移植已经被用于治疗如急性心肌梗死、心力衰竭等心脏疾病,其可以提高心功能、促进新生血管的形成和对心脏生理间接影响。被研究的干细胞包括胚胎干细胞、胎儿心肌细胞、骨骼肌肌原细胞、骨髓干细胞、外周血CD34 细胞、内皮祖细胞、心肌祖细胞和成纤维细胞。虽然干细胞治疗心力衰竭是一项革命性进展,但还有许多问题期待解决,比如说何种人群适合做干细胞治疗、移植细胞种类、移植方式、移植细胞数目和疗效的评估等都还没有明确。现从干细胞类型,移植后的效果及移植的方法等方面做一综述。     

综合护理在老年髋关节置换术患者中的应用

目的：探讨综合护理在老年髋关节置换术中的应用效果。方法将68例老年髋关节置换术患者按住院号随机分为对照组和观察组各34例,对照组采用常规手术及护理,观察组在对照组的基础上实施综合护理干预。对两组患者干预后髋关节Harris评分、感染、便秘、电解质紊乱等并发症的发生率及患者满意度进行比较。结果观察组患者关节活动度、功能、疼痛、畸形评分分别为(4.35±0.44),(40.91±2.30),(40.58±1.18),(3.60±0.23)分,均高于对照组评分[(3.88±0.18),(39.32±2.48),(39.00±1.37),(3.41±0.36)分],观察组关节功能恢复情况优于对照组,差异有统计学意义(t值分别为5.689,2.379,5.114,2.512;P<0.05)。观察组患者感染、电解质紊乱、便秘及其他并发症的发生率分别为2.9%,2.9%,5.9%,5.9%,低于对照组的17.6%,17.6%,23.5%,23.5%,差异有统计学意义(χ2值分别为3.981,3.981,4.221,4.221;P<0.05)。干预后观察组患者基础护理、专科护理、服务态度、健康教育、总体满意度分别为(28.88±0.91),(29.06±0.81),(18.50±1.19),(18.65±1.04),(95.18±2.89)分,高于对照组,差异有统计学意义(P<0.01)。结论对老年髋关节置换术患者实施综合护理,能够提高患者的术后康复质量,减少并发症的发生,提高患者满意度。     

Evaluating the impact of rehabilitation nursing intervention on quality of life in patients with burn injuries: A protocol for systematic review and meta-analysis

Background:Despite the availability of pharmacological intervention, patients with burn injuries experience pain during the treatment of wounds. Supplementary rehabilitation nursing intervention are required to enhance the wellbeing of patients sustaining injuries from burns. The present study aims to conduct a systematic exploration of the impact of rehabilitation nursing intervention on the wellbeing in patients sustaining burn injuries.Methods:The electronic databases listed below will be searched systematically: PubMed, EMBASE, CINAHL, Cochrane Library, Web of Science, Scopus, China National Knowledge Infrastructure, and WanFang database. All the databases will be searched from their inauguration to November 2020. There will be no language constraints. Independent undertaking by 2 authors will select studies, extract data from selected studies, and assess the quality of the included studies. All disagreements will be resolved through discussion, or by consulting a third independent author. This study will make use of RevMan 5.3 software to perform statistical analysis.Results:The present protocol summarizes high-quality evidence to assess the impact of rehabilitation nursing intervention on the wellbeing of patients sustaining burn injuries.Conclusion:The results of the present protocol has the potential to present evidence to assess whether rehabilitation nursing intervention can enhance the wellbeing of patients sustaining burn injuries.Registration number:November 17, 2020.osf.io/t6b8c/. (https://osf.io/t6b8c/).     

应变率成像评价自体外周血干细胞移植术后心肌梗死患者左室局部心肌功能的临床研究

目的探讨应变（SI）及应变率成像（SRI）在急性心肌梗死（AMI）患者自体外周血干细胞移植治疗前、后左室局部心肌功能定量评价中的应用价值。方法共有65例AMI患者入选本项前瞻性、非随机、开放试验（其中35例患者为细胞移植组，30例为常规治疗组）。应用SRI、SI和多普勒速度成像（TVI）测定细胞移植组、常规治疗组治疗前、后及30名健康人的左室壁各节段的SI、SRI及TVI的参数变化。结果①65例AMI患者的589个缺血节段的心肌收缩期峰值应变率（PSSR）、舒张早期峰值应变率（PESR）、收缩期峰值应变（PSS）、心肌收缩期峰值速度（VS）和舒张早期峰值速度（Ve）显著降低，舒张晚期峰值应变率（PASR）和舒张晚期峰值速度（Va）变化差异无统计学意义。SRI和SI检出缺血心肌的敏感性、特异性及准确性明显高于TVI[（90％、91％、92％）比（71％、69％、71％），P〈0．01]。②细胞移植组随访期305个经治疗缺血心肌节段中，244个节段的PSSR、PESR、PSS、Vs及ve较术前显著增高或恢复正常，常规治疗组随访期284个经治疗缺血节段中，169个节段的PSSR、PESR、PSS、Vs及Ve较术前显著增高或恢复正常，但两组治疗后改善的缺血心肌节段数比例及SRI、TVI参数比较差异有统计学意义（P〈0．01）。结论SRI和SI能够无创定量评价冠心病缺血心肌节段的运动异常，为临床客观评价冠脉内自体干细胞移植术疗效提供了一种早期无创、敏感、有效的定量分析手段。     

The reliability of evaluation of hip muscle strength in rehabilitation robot walking training

[Purpose] The primary purpose of this study was to evaluate the intraclass correlation coefficient in obtaining the torque of the hip muscle strength during a robot-assisted rehabilitation treatment. [Subjects] Twenty-four patients (15 males, 9 females) with spinal cord injury participated in the study. [Methods] The subjects were asked to walk during robot-assisted rehabilitation, and the torque of the muscle strength which was measured at hip joint flexion angles of −15, −10, −5, 0, 5, 10, 15, 20, 25, and 30 degrees. [Results] The intraclass correlation coefficient of the torque of the hip muscle strength measured by the rehabilitation training robot was excellent. [Conclusion] Our results show that measurement of torque can be used as an objective assessment of treatment with RAT.Key words: Hip muscle strength, Robot-assisted rehabilitation