全文获取类型
收费全文 | 63390篇 |
免费 | 4580篇 |
国内免费 | 333篇 |
专业分类
耳鼻咽喉 | 635篇 |
儿科学 | 1603篇 |
妇产科学 | 1544篇 |
基础医学 | 7856篇 |
口腔科学 | 1538篇 |
临床医学 | 6364篇 |
内科学 | 14395篇 |
皮肤病学 | 810篇 |
神经病学 | 5001篇 |
特种医学 | 1919篇 |
外国民族医学 | 2篇 |
外科学 | 9745篇 |
综合类 | 1019篇 |
现状与发展 | 1篇 |
一般理论 | 103篇 |
预防医学 | 5255篇 |
眼科学 | 1859篇 |
药学 | 4432篇 |
中国医学 | 146篇 |
肿瘤学 | 4076篇 |
出版年
2023年 | 292篇 |
2022年 | 465篇 |
2021年 | 1157篇 |
2020年 | 725篇 |
2019年 | 1010篇 |
2018年 | 1246篇 |
2017年 | 849篇 |
2016年 | 969篇 |
2015年 | 1138篇 |
2014年 | 1775篇 |
2013年 | 2813篇 |
2012年 | 3782篇 |
2011年 | 4122篇 |
2010年 | 2348篇 |
2009年 | 2193篇 |
2008年 | 4017篇 |
2007年 | 4201篇 |
2006年 | 4023篇 |
2005年 | 4114篇 |
2004年 | 3842篇 |
2003年 | 3454篇 |
2002年 | 3415篇 |
2001年 | 730篇 |
2000年 | 623篇 |
1999年 | 722篇 |
1998年 | 741篇 |
1997年 | 609篇 |
1996年 | 492篇 |
1995年 | 491篇 |
1994年 | 466篇 |
1993年 | 440篇 |
1992年 | 531篇 |
1991年 | 510篇 |
1990年 | 417篇 |
1989年 | 438篇 |
1988年 | 396篇 |
1987年 | 373篇 |
1986年 | 357篇 |
1985年 | 420篇 |
1984年 | 433篇 |
1983年 | 396篇 |
1982年 | 529篇 |
1981年 | 443篇 |
1980年 | 485篇 |
1979年 | 303篇 |
1978年 | 322篇 |
1977年 | 321篇 |
1976年 | 261篇 |
1975年 | 287篇 |
1974年 | 247篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
101.
R Jeyamani N K Shyamkumar Kumar Narayanan H S Subhash Biju George George Kurian 《Indian journal of gastroenterology》2003,22(4):147-148
We report a 40-year-old man with rheumatic heart disease who presented with abdominal pain for three weeks and hematemesis for 24 hours. CT scan showed a large splenic artery aneurysm without evidence of pancreatitis. Mycotic aneurysm due to infective endocarditis was considered and confirmed by echocardiogram, which showed aortic and mitral valve regurgitation and vegetations. He was managed successfully with coil embolization of the aneurysm and antibiotics. 相似文献
102.
103.
Barry W McColl Ailsa L McGregor Andrew Wong Julian D Harris Andrea Amalfitano Sandra Magnoni Andrew H Baker George Dickson Karen Horsburgh 《Journal of cerebral blood flow and metabolism》2007,27(3):477-487
Apolipoprotein E (apoE, protein; APOE, gene) is the major lipid-transport protein in the brain and plays an important role in modulating the outcome and regenerative processes after acute brain injury. The aim of the present study was to determine if gene transfer of the epsilon3 form of APOE improves outcome in a murine model of transient focal cerebral ischaemia. Mice received an intrastriatal injection of vehicle, a second-generation adenoviral vector containing the green fluorescent protein gene (Ad-GFP) or a vector containing the APOE epsilon3 gene (Ad-APOE) 3 days before 60 mins focal ischaemia. Green fluorescent protein expression was observed in cells throughout the striatum and subcortical white matter indicating successful gene transfer and expression. ApoE levels in the brain were significantly increased after Ad-APOE compared with Ad-GFP or vehicle treatment. Ad-APOE treatment reduced the volume of ischaemic damage by 50% compared with Ad-GFP or vehicle treatment (13+/-3 versus 29+/-4 versus 27+/-5 mm(3)). The extent of postischaemic apoE immunoreactivity was enhanced in Ad-APOE compared with Ad-GFP or vehicle treated mice. These results show the ability of APOE gene transfer to markedly improve outcome after cerebral ischaemia and suggest that modulating apoE levels may be a potential strategy in human stroke therapy. 相似文献
104.
105.
106.
107.
Dr. George Soh 《Australian and New Zealand journal of public health》1992,16(1):103-106
Abstract: This study examined physical and financial arrangements for medical care of institutionalised elderly people in Singapore. Chief administrators of all long-term care facilities were interviewed on the existing arrangements for medical care of their residents. Results showed that 66 out of a total of 68 (97%) homes arranged medical care for residents. Of those, 29 homes offered on-site medical care with alternative arrangements when the in-house facilities were not operating. While government-owned homes would pay for all medical costs incurred by their residents, over 48% of voluntary homes and 87% of commercial homes required residents to be financially responsible for their care. The availability of financial support given to residents for payment of medical care was found to be associated with the type of sponsorship of the homes. While there was adequate physical access to medical care, the lack of financial support would pose a potential barrier to use of medical care for institutionalised elderly people. 相似文献
108.
109.
Irfan Soykan Irene Sarosiek Jeannie Shifflett George F. Wooten Dr. Richard W. McCallum 《Movement disorders》1997,12(6):952-957
This study investigated whether domperidone could improve gastrointestinal symptoms in patients with Parkinson's disease who were receiving levodopa therapy. A total of 11 patients were studied. Following a baseline gastric emptying test, patients were treated with a starting dose of domperidone 20 mg p.o. q.i.d. A follow-up gastric emptying test was repeated at least 4 months after starting domperidone therapy. At the beginning and at each 3-month follow-up visit, symptoms of nausea, vomiting, anorexia, abdominal bloating, heartburn, regurgitation, dysphagia, and constipation were evaluated and scored on a scale of 0–3. The overall mean follow-up period was 3 years. Compared with their baseline evaluation, patients experienced a significant improvement in all symptoms (p < 0.05) except dysphagia and constipation. Gastric emptying of an isotope-labeled solid meal was significantly faster, with a baseline result of 60.2 ± 6.4% retention of isotope 2 h after the meal compared with 37.0 ± 2.2% retention during domperidone therapy (p < 0.05). Patients' global assessment of Parkinson's disease remained stable or improved. Serum prolactin was elevated in all patients after domperidone therapy (p < 0.05). Domperidone therapy significantly reduces upper gastrointestinal symptoms and accelerates gastric emptying of a solid meal, but does not interfere with response to antiparkinsonism treatment. 相似文献
110.
Five-Year Outcome After Epilepsy Surgery in Nonmonitored and Monitored Surgical Candidates 总被引:9,自引:9,他引:0
Mark D. Holmes† Carl B. Dodrill†‡ Linda M. Ojemann †‡ George A. Ojemann†‡ 《Epilepsia》1996,37(8):748-752
Summary: Purpose : We wished to compare outcome 5 years after temporal lobectomy in 28 patients selected for surgery on the basis of interictal EEG patterns with that in 46 patients who underwent EEG-video monitoring studies as part of their preoperative evaluation during the same era.
Methods : The 28 nonmonitored patients had interictal EEG patterns that demonstrated a consistent, unilateral, anterior-midtemporal epileptiform focus, without discordant findings from other studies. Outcomes were assessed for years 4 and 5 after operation.
Results : Twenty-six of 28 (92.9%) nonmonitored patients were seizure-free or had at least 75% reduction in seizures. Twenty-nine of 46 (63.0%) monitored patients were seizure-free or had at least 75% reduction in seizures. Preoperative interictal EEGs of 29 of these patients showed independently localized bitemporal, ex-tratemporal, midposterior temporal, or diffuse epileptiform patterns. The remaining 17 monitored patients had preoperative strictly unilateral anterior-midtemporal interictal discharges, and their outcome was comparable to the nonmonitored group, with 15 (88.8%) seizure-free or with at least 75% reduction in seizures.
Conclusions : A proportion of candidates for epilepsy surgery can be selected without ictal recordings provided that interictal EEGs demonstrate consistent unilateral anterior-midtemporal epileptiform discharges and that other data are not discordant. 相似文献
Methods : The 28 nonmonitored patients had interictal EEG patterns that demonstrated a consistent, unilateral, anterior-midtemporal epileptiform focus, without discordant findings from other studies. Outcomes were assessed for years 4 and 5 after operation.
Results : Twenty-six of 28 (92.9%) nonmonitored patients were seizure-free or had at least 75% reduction in seizures. Twenty-nine of 46 (63.0%) monitored patients were seizure-free or had at least 75% reduction in seizures. Preoperative interictal EEGs of 29 of these patients showed independently localized bitemporal, ex-tratemporal, midposterior temporal, or diffuse epileptiform patterns. The remaining 17 monitored patients had preoperative strictly unilateral anterior-midtemporal interictal discharges, and their outcome was comparable to the nonmonitored group, with 15 (88.8%) seizure-free or with at least 75% reduction in seizures.
Conclusions : A proportion of candidates for epilepsy surgery can be selected without ictal recordings provided that interictal EEGs demonstrate consistent unilateral anterior-midtemporal epileptiform discharges and that other data are not discordant. 相似文献