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V. Jayanthi S. Malathi S. Jeevan Kumar N. Dinakaran B. Ramathilakam N. Madanagopalan 《Indian Journal of Thoracic and Cardiovascular Surgery》1993,9(1):26-30
Ten patients with progressive systemic sclerosis underwent clinical, radiological and manometric evaluation for oesophageal
dysfunction. Seven had typical dermatological features of this disease. Eight had symptoms of gastroesophageal reflux. Barium
oesophagogram showed sluggish or absent peristalsis with delayed emptying of barium in six. Motility disturbances noted on
barium oesophagogram were confirmed by oesophageal manometry which proved to be the most sensitive test in diagnosis of progessive
systemic sclerosis. 相似文献
94.
Basal thumb arthritis is a common condition seen in hand clinics across the United Kingdom and is often associated with other pathological conditions such as carpal tunnel syndrome and scaphotrapezial arthritis. Typically, patients complain of pain localised to the base of the thumb. This pain is often activity related, particularly after excessive use involving forceful pinch. A detailed history and examination is normally all that is needed to make the diagnosis. Provocative manoeuvres may be helpful in localising symptoms to the basal joint with degenerative changes or synovitis. Radiographs are useful for confirming the diagnosis and staging the disease in order to plan for surgery. The mainstay of initial treatment of basal thumb arthritis of any stage is activity modifications, rest, nonsteroidal anti-inflammatory drugs, exercises and splinting. A variety of surgical procedures are available to treat the condition when conservative measures have failed, in order to control symptoms and improve function. We review the current literature and discuss the clinical aspects of this condition, staging, and treatment options available, and the difficulties treating this group of patients. 相似文献
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Frölich MA Arabshahi A Katholi C Prasain J Barnes S 《Journal of clinical anesthesia》2011,23(3):218-223
Study Objective
To study the effect of intravenous (IV) sedation on blood pressure (BP), heart rate (HR), and respiratory rates (RR) to determine if IV sedatives differ with respect to their effect on BP, HR, and RR.Design
Prospective, randomized, single-blinded, placebo-controlled study.Setting
Monitored patient care room at a clinical research center.Subjects
60 healthy ASA physical status 1 volunteers.Interventions
Subjects were randomized to receive, in increasing doses, one of three IV sedatives: propofol, midazolam, or dexmedetomidine; or saline control.Measurements
Blood pressure (systolic, diastolic), HR, and RR were recorded.Main Results
A significant dose-dependent BP reduction occurred with dexmedetomidine and, to a lesser degree, with propofol; and there was good agreement of predicted versus measured drug concentrations for all sedatives. Blood pressure and HR of participants who received midazolam did not change.Conclusions
When administered in sedative doses, dexmedetomidine and, to a lesser extent, midazolam, reduces BP in a dose-dependent fashion. Dexmedetomidine also reduces HR. Midazolam does not affect BP or HR. 相似文献98.
Sarangapani A Kini R Chitra S Pugazhendhi T Jeevan Kumar S 《The Indian journal of surgery》2011,73(4):307-308
Intramural metastasis to the stomach (IMMS) from carcinoma esophagus, excluding direct invasion and spread to the stomach,
is relatively uncommon. Diagnosis of IMMS is based on histological criteria, and it is associated with poor prognosis (Takubo
et al. Cancer 65:1816–1819, 1990]. We report two patients of SCC oesophagus in whom intramural metastasis to stomach has occurred. 相似文献
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Baker JB Dutta D Watson D Maddala T Munneke BM Shak S Rowinsky EK Xu LA Harbison CT Clark EA Mauro DJ Khambata-Ford S 《British journal of cancer》2011,104(3):488-495