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There are several reports of beneficial effects of ACE inhibitors in both primary and secondary pulmonary hypertension. However the effect of ACE inhibitors in mitral stenosis is not documented. The authors report three patients with severe mitral stenosis in whom surgery was delayed. They had initial symptomatic improvement with diuretics and sodium restriction, but had recurrence of their symptoms while on treatment. Enalapril not only relieved their symptoms in particular exertional dyspnoea and haemoptysis but prevented recurrence and improved their effort tolerance without causing excessive fall of blood pressure or impairment of renal function. 相似文献
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A cluster randomized trial on improving nurses’ detection and management of elder abuse and neglect (I‐NEED): study protocol
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Debbie Ann Loh MMedSci Wan Yuen Choo MMedSc MAppStats PhD Noran Naqiah Hairi MBBS MPH PhD Sajaratulnisah Othman MBBS MFamMed PhD Farizah Mohd Hairi MBBS MPH DSc Fadzilah Hanum Mohd Mydin MBBS MFamMed Siti Nur Illiani Jaafar MNSc RN Maw Pin Tan MD MBBS MRCP Zainudin Mohd Ali MD MPH MPH Suriyati Abdul Aziz MD MPH Rohaya Ramli MD MPH Rosmala Mohamad MD Zaiton Lal Mohammad MBBS MPH Norlela Hassan RN Patricia Brownell MSW PhD Awang Bulgiba MBBS MMed PhD 《Journal of advanced nursing》2015,71(11):2661-2672
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Jennifer G.M. Chantler Roy B. Judge Joseph E.A. Palamara Jaafar Abduo 《Dental materials》2021,37(6):e382-e390
ObjectiveThe purpose of this laboratory study is to evaluate the application of a pre-sintered surface augmentation to zirconia (Zir) and lithium disilicate (LDS) ceramics on the delamination strength of adhesive resin cement. The applied surface augmentation was the ruling of lines to the pre-sintered surface of the ceramics.MethodsNinety milled Zir and sixty pressed LDS specimens (3 mm × 0.5 mm × 25 mm) were created and divided into five groups (n = 30). Group 1: Zir no surface treatment (control Zir-NT); Group 2: Zir airborne particle abraded (Zir-APA) with 30 μm CoJet; Group 3: Zir pre-sintered surface augmentation (Zir-SA); Group 4: LDS etched (control LDS-etched) and; Group 5: LDS with pre-sintered surface augmentation and etching (LDS-SA). A resin adhesive cement (3 mm × 1 mm × 8 mm) was then applied and cured to the ceramic specimens. The delamination strength values of the resin cement from the ceramic were recorded. The delamination strength data were analysed statistically using one-way ANOVA and Turkey post hoc analysis.ResultsThe mean delamination strength and standard deviation, when comparing only the Zir-SA to the resin cement were statistically different (p < 0.001); Zir-SA 63.42 ± 11.85, Zir-NT 26.82 ± 12.07, and Zir-APA 48.11 ± 17.85 MPa. Comparison between LDS groups were not significantly different (p = 0.193); LDS-etched 33.49 ± 16.07 and LDS-SA 28.83 ± 10.15 MPa. The delaminated Weibull modulus was highest for surface augmentation Zir specimens (m = 13.56) but decreasing to less than half for Zir-APA (m = 6.27) and Zir-NT (m = 5.68). The Weibull values for the LDS-SA and LDS-etched specimens was 5.63 and 3.38 respectively.SignificanceIncorporating the pre-sintered surface augmentation to zirconia improved the delamination strength and reliability of Zir to the resin cement but not for LDS. 相似文献
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Mostapha Boussouga Jalal Boukhriss Abdeloihab Jaafar Khalid H. Lazrak 《The Journal of foot and ankle surgery》2010,49(3):298.e17-298.e20
The authors report a case of a dorsal dislocation of the fifth metatarsophalangeal joint that could not be reduced by closed manipulation, and instead required open reduction with Kirschner-wire fixation to maintain alignment. Although metatarsophalangeal joint dislocation is not unheard of, it is not common for the deformity to resist efforts at closed reduction and immobilization or percutaneous pin fixation. One year after surgery, the patient described in this article had returned to his baseline activity level, and was ambulating without pain while demonstrating full range of motion in the fifth metatarsophalangeal joint. 相似文献
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Nicolas Mayeur Lionel Rostaing Marie B Nogier Acil Jaafar Olivier Cointault Nassim Kamar Jean M Conil Olivier Fourcade Laurence Lavayssiere 《Critical care (London, England)》2010,14(3):R115
Introduction
Cystatin C could be a relevant residual glomerular filtration rate marker during hemodialysis (HD), and a high cytokine plasma (p) rate is associated with an increase in mortality during sepsis. To the best of our knowledge, cytokines and cystatin C kinetics during and after HD during sepsis have never been studied. In this study, we described p cytokines and cystatin C variations during and after hemodialysis in septic-shock patients with acute kidney injury (AKI). 相似文献89.
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Sommet A Delpierre C Cuzin L Jaafar A Marchou B Massip P 《La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne》2003,24(6):350-357
INTRODUCTION: This retrospective study analyses causes as well as clinical, immunological and virological consequences of antiretroviral treatment interruptions (Ti) of more than 30 days in HIV-1 infected adults. METHODS: This causes were classified as related to drug toxicity, therapeutic or adherence failure. We studied therapeutic regimens before Ti and after treatment reinitiation (TR), clinical events related to Ti, CD4 cells and viral loads before Ti and at months 3, 6, 9, and 12 after TR. RESULTS: Out of 188 Ti analysed, 42.6% were related to therapeutic failure, 33.5% to drug toxicity, and 23.9% to adherence failure. Eight Aids defining clinical events were reported during Ti, in patients with low CD4 cells and high viral load (P < 0.05). Viral loads evolution after TR was better if Ti was related to treatment failure (P < 0.05), was prolonged (P < 0.05), and if CD4 cells were high before Ti and at TR (P < 0.05). Median CD4 cells was of 296/mm(3) at month 12 after TR vs 382 before Ti. CONCLUSIONS: Ti consequences are strongly related to CD4 cells, which decrease sharply during Ti, increasing Aids defining events probability. Prospective randomised clinical studies are needed to define usefulness of Ti. 相似文献