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961.
Ferro HH González EB 《Kidney international》2012,81(12):1273; author reply 1273-1273; author reply 1274
962.
Hemodialysis catheterization through the right internal jugular vein (IJV) is widely used for mid- to long-term hemodialysis for patients with renal failure. The purpose of this report is to address a serious complication in conjunction with this procedure. This is a case report of an iatrogenic jugular-carotid fistula (JCF) and a method for rectifying such a vascular conundrum, using endovascular techniques. We describe the technique used to achieve closure of the fistula as well a review of the literature. An 82-year-old woman with history of congestive heart failure, chronic renal failure, and diabetes mellitus developed an iatrogenic arteriovenous fistula, following an attempt of canalizing the right IJV. The patient was treated using three different stents, which achieved closure of the fistula. Venous catheter misplacement into an artery is a serious complication. Early endovascular treatment should be considered for a JCF. 相似文献
963.
Alexis Sánchez Omaira Rodríguez Elias Nakhal Hugo Davila Rair Valero Renata Sánchez Romina Pena Maria F. Visconti 《Journal of robotic surgery》2012,6(3):213-216
Minimally invasive surgery has become the gold standard for the treatment of achalasia. The incorporation of robotic technology can improve many limitations of laparoscopic surgery, through, for example, the availability of three-dimensional vision, increasing the degrees of movement, avoiding the fulcrum effect and optimizing ergonomics. The aim of this study was to compare robotic-assisted laparoscopic Heller myotomy (RAHM) with laparoscopic Heller myotomy (LHM) in terms of efficacy and safety. Thirty-one patients with diagnosis of achalasia confirmed by esophagogram and manometry were included. Dysphagia and weight loss were the main complaints in both groups. 18 patients were treated with LHM and 13 patients with RAHM. There was no difference in mean operative time (76?±?13 vs. 79?±?20?min; P?=?0.73). Intraoperative complications were less frequent in the robotic-assisted procedures (5.5% vs. 0%); however, this was a non-significant difference. 94.5?C100% of patients had relief of their symptoms. We conclude that RAHM is a safe and effective procedure. The operative time is no longer than in LHM, but it is necessary to evaluate the technique in randomized clinical trials to determine its advantages in terms of intraoperative complications. 相似文献
964.
Dionis de Castro Dutra Machado Glenda Crispim Lima Rodrigo Souza dos Santos Amanda Júlia Bezerra Ramos Cáio César Menezes de Sousa Rayele Pricila Moreira dos Santos Karyna Kelly Oliveira Coelho Mauricio Cagy Marco Orsini Victor Hugo Bastos 《Journal of Physical Therapy Science》2014,26(6):801-804
[Purpose] The study analyzed the electroencephalographic (EEG) data of the central
cortical areas, during execution of the motor gestures of feeding, activation of the
system of mirror neurons, and imagery between a right hemiparetic volunteer (RHV) and a
healthy volunteer (HV). [Subjects and Methods] The volunteers’ EEG data were recorded with
their eyes open for 4 minutes while they performed five experimental tasks. [Results] The
alpha band, absolute power value of HV was lower than that of RHV. In the beta band,
during the practice condition, there was an increase in the magnitude of the absolute
power value of HV at T3, possibly because T3 is representative of secondary motor areas
that work with cortical neurons related to planning and organizing sequence of movements
performed by the hands. The gamma band is related to the state of preparation for movement
and memory. The results of this study indicate that there was increased activation of the
gamma frequency band of HV. [Conclusion] The findings of this study have revealed the
changes in pattern characteristics of each band which may be associated with the brain
injury of the hemiparetic patient.Key words: Electroencephalography, Hemiparetic, Rehabilitation 相似文献
965.
966.
Hugo Georges Arthur Dupuis Ala Chebbi Louis Surlemont Olivier Rigal Frdric Di Fiore Christian Pfister Franois-Xavier Nouhaud 《Translational andrology and urology》2021,10(6):2418
Backgroundimmunotherapy became the first line treatment of metastatic renal cell carcinoma (mRCC). Nevertheless, a better understanding of the specificities of targeted therapies (TT) in the elderly population could be helpful in order to improve the management of mRCC in this population. The aim of this retrospective study was to assess efficacy and safety of sunitinib and sorafenib used as first-line TT in 70 years older patients compared to younger patients.MethodsData were retrospectively collected for all consecutive mRCC patients receiving first line TT treatment by sunitinib or sorafenib for mRCC from January 2006 to November 2017. Patients were divided into two groups according to the age using a cut-off at 70 years old. Median progression-free survival (PFS) and overall survival (OS) were estimated by Kaplan-Meier method and compared using log-rank test.ResultsIn total, 147 patients were included; 94 (63.9%) were <70 and 53 (36.1%) were 70 years old or more. First line TT used was sunitinib in 123 (83.7%) patients or sorafenib in 24 (16.3%) patients. Median PFS was 8 months for elderly patients vs. 6 in younger group (P=0.68). Median OS were 26 vs. 36 months (P=0.08). Severe induced toxicity was more frequent among elderly patients: 34 (64.2%) vs. 46 patients (48.9%) (P=0.07). Rate of treatment discontinuation due to toxicity was 22 patients (23.4%) in younger group vs. 28 patients (52.8%) in the elderly group (P=0.0005). Results were similar in the 2 groups regarding the type of toxicities.ConclusionsOur results suggest similar efficacy of anti-vascular endothelial growth factor (VEGF) agents as first-line treatment for mRCC among younger and older patients with an age cut-off of 70 years. Safety results suggest that these drugs can be safely used for older patients with a need of caution regarding toxicity prevention. 相似文献
967.
968.
969.
Hugo You-Hsien Lin Su-Chu Lee Sheng-Fung Lin Hui-Hua Hsiao Yi-Chang Liu Wen-Chi Yang Daw-Yang Hwang Chi-Chih Hung Hung-Chun Chen Jinn-Yuh Guh 《The Kaohsiung journal of medical sciences》2013,29(6):304-311
Cisplatin-induced acute kidney injury (AKI) is a major concern among clinicians in prescribing cisplatin-based chemotherapy. This study evaluated and compared the ability of urinary biomarkers, including urinary neutrophil gelatinase-associated lipocalin (NGAL), cystatin C, and the urinary albumin to creatinine ratio (ACR) to predict cisplatin-induced AKI. Thirty-three cancer patients receiving cisplatin-based chemotherapy were prospectively studied, including 10 (30%) who developed AKI (the study group). Changes of urinary biomarkers were compared at 4 hours, 8 hours, and 12 hours, and 1 day, 2 days, 3 days, and 4 days after cisplatin intravenous infusions (75 mg/m2) versus the baseline. There was a significant increase in urinary NGAL levels from 12 hours to 4 days (p < 0.05) compared to baseline after cisplatin infusion in the AKI group. The magnitude of these changes over time differed significantly by group (p < 0.001). The area under the receiver operating curve describing the relationship between urinary NGAL levels and AKI within 12 hours was 0.865 (95% confidence interval = 0.691–1.000). Urinary NGAL levels independently predicted AKI 12 hours after cisplatin (p = 0.045) after adjustments for age, gender, body mass index, baseline serum creatinine, and urinary total protein. Urinary NGAL levels may be an early biomarker of AKI in patients receiving cisplatin-based treatment. 相似文献
970.
Tea Reljic Rachel Pyngolil Rami S. Komrokji Jeffrey E. Lancet Hugo F. Fernandez Benjamin Djulbegovic Ambuj Kumar 《British journal of haematology》2013,163(3):315-325
Evidence regarding the efficacy of gemtuzumab ozogamicin (GO) addition to standard induction chemotherapy in newly diagnosed acute myeloid leukaemia (AML) is conflicting. This systematic review aimed to identify and summarize all evidence regarding the benefits and harms of adding GO to conventional chemotherapy for induction treatment of AML. A comprehensive literature search of two databases (PUBMED and Cochrane) from inception up to November 22, 2012, and 4 years of proceedings from four major haematology/oncology conferences was undertaken. Endpoints included benefits (complete remission, relapse‐free, event‐free, and overall survival), and harms (early mortality and incidence of hepatic veno‐occlusive disease/sinusoidal obstructive syndrome). Seven trials (3942 patients) met all inclusion criteria. Addition of GO showed improved relapse‐free [Hazard Ratio (HR) = 0·84 (95% confidence interval (CI) 0·71–0·99)] and event‐free survival [HR = 0·59 (95%CI 0·48–0·74)] but not overall survival [HR = 0·95 (95%CI 0·83–1·08)]. Addition of GO resulted in higher rate of early mortality [Risk Ratio = 1·60 (95%CI 1·07–2·39)]. Improved overall survival was observed in studies using a lower cumulative GO dose (<6 mg/m2) [HR = 0·89 (95%CI 0·81–0·99)]. Addition of GO to conventional chemotherapy as induction therapy may improve relapse‐free and event‐free survival, but does not impact overall survival and significantly increases early mortality in AML. 相似文献