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991.
Francesco Giannini MD Matteo Pagnesi MD Gianluca Campo MD PhD Michael Donahue MD Luca A. Ferri MD Carlo Briguori MD PhD Giulio G. Stefanini MD PhD Raffaele Scardala MD Gennaro Sardella MD Salvatore De Rosa MD PhD Filippo Figini MD Alberto Monello MD Luigi E. Pastormerlo MD Luca Testa MD PhD Annamaria Nicolino MD Alfonso Ielasi MD Alessandro Durante MD Angelo Leone MD Giorgios Tzanis MD Antonio Mangieri MD Giovanni Ciccarelli MD Martina Briani MD Bernhard Reimers MD Andrea Ceccacci MD Ciro Indolfi MD Imad Sheiban MD Cataldo Palmieri MD Francesco Bedogni MD Maurizio Tespili MD Azeem Latib MD Francesco Gallo Antonio Colombo MD 《Catheterization and cardiovascular interventions》2021,97(3):411-420
992.
Federico Simonetto MD Paola A. M. Purita MD Massimiliano Malerba MD Marco Barbierato MD Andrea Pascotto MD Domenico Mangino MD Chiara Zanchettin MD Giuseppe Tarantini MD Gino Gerosa MD Augusto D'Onofrio MD Carlo Cernetti MD Luca Favero MD Alessandro Daniotti MD Giuseppe Minniti MD Francesco Caprioglio MD Giovanna Erente MD Tommaso Hinna Danesi MD Anna Chiara Frigo MD Federico Ronco MD 《Catheterization and cardiovascular interventions》2021,97(4):714-722
993.
Arif A. Khokhar BMBCh Alessandra Laricchia MD Francesco Ponticelli MD Won-Keun Kim MD Francesco Gallo Damiano Regazzoli MD Marco Toselli MD Alessandro Sticchi MD Rossella Ruggiero MD Alberto Cereda MD Adriana Zlahoda-Huzior MD Andrea Fisicaro MD Ilja Gardi MD Antonio Mangieri MD Bernhard Reimers MD Dariusz Dudek MD Antonio Colombo MD Francesco Giannini MD 《Catheterization and cardiovascular interventions》2021,98(3):595-604
994.
Ambulatory blood pressure and risk of new‐onset atrial fibrillation in treated hypertensive patients
Francesca Coccina Anna M. Pierdomenico Umberto Ianni Matteo De Rosa Andrea De Luca Davide Pirro Jacopo Pizzicannella Oriana Trubiani Francesco Cipollone Giulia Renda Sante D. Pierdomenico 《Journal of clinical hypertension (Greenwich, Conn.)》2021,23(1):147-152
The aim of this study was to evaluate the influence of clinic and ambulatory blood pressure (BP) on the occurrence of new‐onset atrial fibrillation (AF) in treated hypertensive patients. We studied 2135 sequential treated hypertensive patients aged >40 years. During the follow‐up (mean 9.7 years, range 0.4–20 years), 116 events (new‐onset AF) occurred. In univariate analysis, clinic, daytime, nighttime, and 24‐h systolic BP were all significantly associated with increased risk of new‐onset AF, that is, hazard ratio (95% confidence interval) per 10 mm Hg increment 1.22 (1.11–1.35), 1.36 (1.21–1.53), 1.42 (1.29–1.57), and 1.42 (1.26–1.60), respectively. After adjustment for various covariates in multivariate analysis, clinic systolic BP was no longer associated with increased risk of new‐onset AF, whereas daytime, nighttime, and 24‐h systolic BP remained significantly associated with outcome, that is, hazard ratio (95% confidence interval) per 10 mm Hg increment 1.09 (0.97–1.23), 1.23 (1.10–1.39), 1.16 (1.03–1.31), and 1.22 (1.06–1.40), respectively. Daytime, nighttime, and 24‐h systolic BP are superior to clinic systolic BP in predicting new‐onset AF in treated hypertensive patients. Future studies are needed to evaluate whether a better control of ambulatory BP might be helpful in reducing the occurrence of new‐onset AF. 相似文献
995.
Francesco Maisano MD Giulio Russo MD PhD Ana Paula Tagliari MD MSc Mara Gavazzoni MD Maurizio Taramasso MD PhD 《Catheterization and cardiovascular interventions》2021,98(6):E971-E976
Optimal transseptal puncture (TSP) position on the interatrial septum as well as proper catheter direction and maneuverability in the left atrium (LA) are key elements for successful mitral valve (MV) interventions. TSP is usually performed from the right femoral vein being more comfortable for the operator and easier to reach the fossa ovalis. In the cases reported, TSP was performed from left femoral vein (LFV) to improve delivery system maneuverability and trajectory inside the LA in the context of MV repair with MitraClip. According to this early experience, LFV approach might be considered as first choice or as an alternative solution in patients in whom a higher position of the delivery system relative to the mitral annulus is needed. 相似文献
996.
Giovanni Maconi Cristina Bosetti Alberta De Monti Ray Kiran Boyapati Edward Shelton Nicole Piazza Anna Maria Carvalhas Gabrielli Marco Vincenzo Lenti Cristina Bezzio Chiara Ricci Salvatore Greco Samanta Romeo Francesco Giangregorio Daniele Gridavilla Fabio Tagliani Alessandro Massari Luca Pastorelli Antonio Di Sabatino Sandro Ardizzone 《Digestive and liver disease》2021,53(3):263-270
BackgroundIt is unclear whether patients with inflammatory bowel disease (IBD) are at increased risk of COVID-19.ObjectivesThis observational study compared the prevalence of COVID-19 symptoms, diagnosis and hospitalization in IBD patients with a control population with non-inflammatory bowel disorders.MethodsThis multicentre study, included 2733 outpatients (1397 IBD patients and 1336 controls), from eight major gastrointestinal centres in Lombardy, Italy. Patients were invited to complete a web-based questionnaire regarding demographic, historical and clinical features over the previous 6 weeks. The prevalence of COVID-19 symptoms, diagnosis and hospitalization for COVID-19 was assessed.Results1810 patients (64%) responded to the questionnaire (941 IBD patients and 869 controls). IBD patients were significantly younger and of male sex than controls. NSAID use and smoking were more frequent in controls. IBD patients were more likely treated with vitamin-D and vaccinated for influenza. Highly probable COVID-19 on the basis of symptoms and signs was less frequent in the IBD group (3.8% vs 6.3%; OR:0.45, 95%CI:0.28–0.75). IBD patients had a lower rate of nasopharyngeal swab-PCR confirmed diagnosis (0.2% vs 1.2%; OR:0.14, 95%CI:0.03–0.67). There was no difference in hospitalization between the groups (0.1% vs 0.6%; OR:0.14, 95%CI:0.02–1.17).ConclusionIBD patients do not have an increased risk of COVID-19 specific symptoms or more severe disease compared with a control group of gastroenterology patients. 相似文献
997.
998.
Gabriele DAmato Maria F. Faienza Valentina Palladino Francesco P. Bianchi Maria P. Natale Robert D. Christensen Paola Giordano Antonio Del Vecchio 《Trasfusione del sangue》2021,19(2):113
BackgroundPreterm neonates are likely to require red blood cell (RBC) transfusion, and extremely low birth weight infants almost invariably receive multiple transfusions. Transfusion-reduction strategies can reduce transfusion rates, and might diminish certain adverse outcomes associated with transfusions.Materials and methodsIn a single centre, we retrospectively evaluated RBC transfusion rates among preterm infants ≤32 weeks’ gestational age (GA), over a 6-year period before and after adopting national transfusion-reduction strategies. We compared demographic data, adverse events, and outcomes between transfused vs not-transfused neonates. Univariate logistic regression was used to evaluate associations between dichotomous outcomes and number of transfusions, and day of first transfusion. Multivariate logistic regression evaluated the correlation between dichotomous outcomes and transfusion as an independent risk factor.ResultsDuring the 6 years studied, 181 infants born at ≤32 weeks’ GA were admitted to our Neonatal Intensive Care Unit of whom 80 (44%) received at least one RBC transfusion. The transfusion rate tended downwards after adopting transfusion-reduction strategies, reaching 31% in 2018. The reduction was largely due to a marked fall in transfusions of neonates born at 29–32 weeks’ GA (p<0.001). The number of transfusions received correlated with odds of having intraventricular haemorrhage (IVH) (OR=1.9; 95% CI: 1.3–2.7; p=0.0001) and the duration of oxygen supplementation (rho=0.51; 95% CI: 0.33–0.66; p≤0.0001). In multivariate logistic regression analysis, transfusion was an independent risk factor for IVH (adjusted OR=7.38; 95% CI: 2.24–24.30; p=0.0001).DiscussionThe application of national, standardised transfusion-reduction strategies was associated with a lower transfusion rate in neonates born at 29–32 weeks’ GA, but was less effective among neonates ≤28 weeks, in whom transfusions appeared to be an independent risk factor for severe IVH. 相似文献
999.
1000.
Nowadays, the growing energy costs and pressing worldwide demand for petroleum-based products create a strong need to develop alternative binders deriving from green and renewable sources. Bio-binders (or bitumen added to bio-based materials) can potentially be a viable alternative for the production of bituminous mixture, promoting the circular economy as well as environmental sustainability principles without reducing the overall performance of the mixture. In this context, the current study focuses on evaluation of the effects of a bio-binder on the mechanical response of asphalt concrete (AC) produced with it. In particular, a 10% bio-oil deriving from a by-product of the paper industry has been blended with a conventional 50/70 penetration grade bitumen to obtain the bio-binder. Moreover, plain bitumen having the same consistency was chosen to produce a reference AC. Two dense-graded AC wearing courses were prepared in the laboratory according to Italian technical specifications. A mechanical characterization in terms of indirect tensile strength, indirect tensile stiffness modulus, fatigue response and permanent deformation resistance was performed on gyratory compacted specimens using both conventional and performance tests. In addition, aging and water sensitivity of the AC specimens were evaluated. Overall results highlight that the AC produced with the bio-binder did not show reduced mechanical properties and it was comparable to the reference AC regardless of aging and water conditioning. This highly encourages the use of bio-binder as a viable alternative in asphalt technology. 相似文献