全文获取类型
收费全文 | 53435篇 |
免费 | 3373篇 |
国内免费 | 268篇 |
专业分类
耳鼻咽喉 | 596篇 |
儿科学 | 1338篇 |
妇产科学 | 1175篇 |
基础医学 | 7544篇 |
口腔科学 | 4485篇 |
临床医学 | 4141篇 |
内科学 | 11254篇 |
皮肤病学 | 1173篇 |
神经病学 | 4266篇 |
特种医学 | 1334篇 |
外国民族医学 | 2篇 |
外科学 | 6546篇 |
综合类 | 510篇 |
一般理论 | 11篇 |
预防医学 | 5557篇 |
眼科学 | 698篇 |
药学 | 3560篇 |
中国医学 | 428篇 |
肿瘤学 | 2458篇 |
出版年
2023年 | 422篇 |
2022年 | 1103篇 |
2021年 | 1917篇 |
2020年 | 1287篇 |
2019年 | 1657篇 |
2018年 | 1943篇 |
2017年 | 1412篇 |
2016年 | 1487篇 |
2015年 | 1799篇 |
2014年 | 2431篇 |
2013年 | 2848篇 |
2012年 | 4263篇 |
2011年 | 4579篇 |
2010年 | 2402篇 |
2009年 | 1920篇 |
2008年 | 3194篇 |
2007年 | 3154篇 |
2006年 | 2767篇 |
2005年 | 2436篇 |
2004年 | 2214篇 |
2003年 | 1937篇 |
2002年 | 1685篇 |
2001年 | 932篇 |
2000年 | 939篇 |
1999年 | 781篇 |
1998年 | 343篇 |
1997年 | 248篇 |
1996年 | 223篇 |
1995年 | 206篇 |
1994年 | 200篇 |
1993年 | 170篇 |
1992年 | 361篇 |
1991年 | 335篇 |
1990年 | 321篇 |
1989年 | 302篇 |
1988年 | 272篇 |
1987年 | 215篇 |
1986年 | 205篇 |
1985年 | 192篇 |
1984年 | 164篇 |
1983年 | 124篇 |
1979年 | 130篇 |
1978年 | 106篇 |
1975年 | 93篇 |
1974年 | 99篇 |
1973年 | 113篇 |
1970年 | 102篇 |
1969年 | 101篇 |
1968年 | 86篇 |
1967年 | 95篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
41.
Amanda Leal Rocha Alessandra Figueiredo De Souza Laiz Fernandes Mendes Nunes Nayara Dias de Souza Cunha Clia Regina Moreira Lanza Denise Vieira Travassos Tarcília Aparecida da Silva 《Pediatric dermatology》2019,36(1):e27-e30
Drug‐induced reactions are complications associated with high mortality and significant morbidity. Stevens–Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are examples of these conditions, which are characterized by skin and mucous lesions. Here, we report a case of a 9‐year‐old girl who presented with blisters associated with an extensive vesicular rash and multiple ulcerations on the lips and oral cavity. A drug‐induced hypersensitivity reaction to antibiotics was suspected, and a diagnosis of TEN was made. The patient was managed with withdrawal of the suspected causative agent, and the oral lesions were treated with low‐level laser therapy (LLLT) and oral hygiene. This case highlights that TEN requires interdisciplinary intervention with dental assistance and follow‐up to improve symptoms, nutrition, systemic condition, and quality of life. 相似文献
42.
43.
John P. Sundberg Kathleen A. Silva Victoria E. Kennedy John J. Wilson Nicholas E. Gott Beth A. Sundberg Derry C. Roopenian 《Experimental dermatology》2019,28(9):1091-1093
2‐deoxy D‐glucose (2DG) was tested for efficacy in treating alopecia areata using the C3H/HeJ skin graft model. 2DG has proven to be efficacious in treatment of various mouse models of autoimmunity with minimal serious side effects noted. This agent has been shown to normalize abnormally activated T‐cell populations while also preventing cell surface expression of NKG2D; key factors defining alopecia areata disease progression. Daily oral ingestion of 2DG via drinking water to mice with patchy or diffuse alopecia areata for 16 weeks failed to prevent expansion of alopecia or cause regrowth of hair in treated mice. Histologically, there were no differences between treated and control groups. These results indicate that, while 2DG is effective for some autoimmune diseases, it was not efficacious for the cell‐mediated autoimmune mouse disease, alopecia areata. 相似文献
44.
Objective
To explore from a gender perspective the association with subjective health of the interaction between education and household arrangements within the framework of social determinants of health placed at the micro and mezzo levels.Methods
The data comes from the Spanish sample of the European Union Statistics on Income and Living Conditions for 2014. Independent logistic regression models for men and women were run to analyze the association with subjective health of the interaction between education and household arrangements. An additive model was run to assess possible advantages over the interaction approach.Results
The interaction models show a lower or even no significant effect on health of household arrangements usually negatively associated with health among individuals with high education, displaying specific patterns according to sex.Conclusions
Health profiles of women and men are more precisely drawn if both social determinants of health are combined. Among the women, the important role was confirmed of both social determinants of health in understanding their health inequalities. Among the men, mainly those with low educational achievement, the interaction revealed that the household was a more meaningful social determinant of health. This could enable the definition of more efficient public policies to reduce health and gender inequalities. 相似文献45.
Luana Lopes Padilha Elcio Oliveira Vianna Andressa Talícia Machado Vale Joelma Ximenes Prado Teixeira Nascimento Antônio Augusto Moura da Silva Cecilia Claudia Costa Ribeiro 《Pediatric allergy and immunology》2020,31(5):480-488
Studies on the exposure of children to sugar-sweetened beverages (SSBs) at an early age may contribute to better understand the common causes and the temporal order of the relationships between obesity and asthma in early childhood. The objective of this study was to estimate the association between SSB and child asthma traits in the 2nd year of life, modeling direct and indirect pathways mediated by the highest BMI-z of the child and allergic inflammation. Data from the BRISA cohort, São Luís-MA, Brazil (n = 1140), were obtained from the baseline and from the follow-up performed at the 2nd year of life. The main explanatory variable was the calories from added sugars in SSBs as a percentage of the total daily energy intake. The outcome child asthma traits was a latent variable deduced from four indicators: medical diagnosis of asthma, wheezing, emergency visit due to intense wheezing, and medical diagnosis of rhinitis. A high percentage of daily calories from sugars added to SSBs was directly associated with higher values of child asthma traits (standardized coefficient (SC = 0.073; P = .030)). High levels of eosinophils were also directly associated with child asthma traits (SC = 0.118; P = .049). No mediation pathways were observed via greater BMI-z or eosinophil counts. Therefore, early exposure of children to SSB may contribute to increased risk of childhood asthma, preceding the link between sugar consumption and overweight/obesity, not yet evident in children in the first 2 years of life. 相似文献
46.
47.
48.
Eduardo Rodrigues‐Pinto Joel Ferreira‐Silva Guilherme Macedo Douglas K. Rex 《Digestive endoscopy》2019,31(5):583-587
Cecal intubation is a critical aspect of effective, complete colonoscopy. Difficult colonoscopy is most often considered as one in which it is challenging or impossible to reach the cecum. It may be a common occurrence due to patient and/or endoscopist factors. Incomplete colonoscopies should be avoided, since patients in this context present an important prevalence of lesions that escape examination. The approach to successful cecal intubation should depend on characterization of the problem as redundant colon or difficult sigmoid colon. Most patients with a prior incomplete colonoscopy can be colonoscoped successfully, if careful attention is paid to technique, using a variety of scopes, colonoscopy methods and additional equipment. Sufficient time should be allotted to make the attempt. 相似文献
49.
50.
Rubens Souza de OLIVEIRA Lanna Jamile Corrêa da COSTA Fernanda Atanaena Gon?alves de ANDRADE Wilson UIEDA Luzia Fátima Alves MARTORELLI Ana Paula de Arruda Geraldes KATAOKA Elizabeth Salbé Travassos da ROSA Pedro Fernando da Costa VASCONCELOS Armando de Souza PEREIRA Ant?nio Ismael Barros do CARMO Marcus Emanuel Barroncas FERNANDES 《Revista do Instituto de Medicina Tropical de S?o Paulo》2015,57(6):497-503
The outbreaks of rabies in humans transmitted by Desmodus rotundus in 2004 and 2005,
in the northeast of the Brazilian State of Para, eastern Amazon basin, made this a
priority area for studies on this zoonosis. Given this, the present study provides
data on this phenomenon in an urban context, in order to assess the possible
circulation of the classic rabies virus (RABV) among bat species in Capanema, a town
in the Amazon basin. Bats were collected, in 2011, with mist nets during the wet and
dry seasons. Samples of brain tissue and blood were collected for virological and
serological survey, respectively. None of the 153 brain tissue samples analyzed
tested positive for RABV infection, but 50.34% (95% CI: 45.67-55.01%) of the serum
samples analyzed were seropositive. Artibeus planirostris was the most common
species, with a high percentage of seropositive individuals (52.46%, 95% CI: 52.31
52.60%). Statistically, equal proportions of seropositive results were obtained in
the rainy and dry seasons (c2 = 0.057, d.f. = 1, p = 0.88). Significantly
higher proportions of males (55.96%, 95% CI: 48.96-62.96%) and adults (52.37%, 95%
CI: 47.35-57.39%) were seropositive. While none of the brain tissue samples tested
positive for infection, the high proportion of seropositive specimens indicates that
RABV may be widespread in this urban area. 相似文献