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S Suri MB BS MD MRCPCH MRCP S Salfield FRCPCH FRCP DCH DObstRCOG P Baxter MA MD FRCP 《Developmental medicine and child neurology》1999,41(4):273-274
Congenital paraplegia, with partial improvement over the first months of life, occurred in a female neonate born at 35 weeks' gestation, whose mother had suffered hypotension and hypoxaemia due to anaphylaxis 12 weeks earlier. Our patient subsequently had an acute encephalopathy during a respiratory illness with later developmental delay. We speculate that the baby's paraplegia resulted from spinal-cord ischaemia in utero. The aim of this report is to describe the spinal presentation. 相似文献
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Weight‐correction of carbon dioxide diffusion coefficient (DCO2) reduces its inter‐individual variability and improves its correlation with blood carbon dioxide levels in neonates receiving high‐frequency oscillatory ventilation
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Gusztav Belteki MD PhD FRCPCH Benjamin Lin BA Colin J. Morley MD FRCPCH 《Pediatric pulmonology》2017,52(10):1316-1322
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Filamin A (FLNA) mutation—A newcomer to the childhood interstitial lung disease (ChILD) classification
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Ashley Rajappan BSc Anna Pearce PhD Hazel M. Inskip PhD Janis Baird PhD Sarah R. Crozier PhD Cyrus Cooper FMedSci Keith M. Godfrey FRCP Graham Roberts MRCPCH DM Jane S.A. Lucas FRCPCH PhD Katharine C. Pike FRCPCH PhD The Southampton Women's Survey Study Group 《Pediatric pulmonology》2017,52(10):1291-1299
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Vinay Bhole MD MRCPCH John G.C. Wright FRCP Joseph V. De Giovanni MD FRCP FRCPCH Rami Dhillon MRCP Paul A. Miller MRCP Tarak Desai MD MRCP Ashish Chikermane MD MRCP Timothy Jones FRCS David J. Barron FRCS William J. Brawn FRCS Oliver Stumper MD PhD 《Catheterization and cardiovascular interventions》2011,77(1):92-98
Objective : To analyze the safety and clinical impact of interventional cardiac catheter procedures in the management of early postoperative problems after completion of an extracardiac Fontan procedure. Background : The mortality after Fontan procedure has consistently decreased over the last decade. The role of interventional catheterization to address early postoperative problems in this setting has not been studied systematically. Methods : Over a 9.7‐year period, 289 patients underwent an extracardiac fenestrated Fontan procedure with two early deaths (0.7%) and takedown in four (1.4%). Twenty‐seven patients (9.3%) underwent 32 interventional cardiac catheter procedures at a median interval of 12.2 (1–30) days. The median weight was 14.5 (13.5–25) kg. The case notes and procedure records were reviewed retrospectively. Results : Fontan pathway obstructions were treated in 11 patients with stent implantation with good results and no complications. Stent fenestration of the Fontan circulation was performed in 16 patients with one episode of transient hemiparesis and one episode of pericardial effusion. Three patients underwent initial balloon dilatation of branch pulmonary arteries or fenestration with little effect and underwent stent treatment 6 (5–9) days later. One patient had device closure of a large atrial fenestration. In one patient, residual anterograde pulmonary blood flow was occluded using a device. There were no deaths and in‐hospital course was improved in all. Conclusion : Interventional cardiac catheter procedures can be performed safely and effectively in the early postoperative period after Fontan completion to address hemodynamic problems. These techniques contribute significantly to achieve a very low mortality and address morbidity after Fontan completion. © 2010 Wiley‐Liss, Inc. 相似文献
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Helen McPherson MBChB Mark Rosenthal MD FRCP FRCPCH Andrew Bush MD FRCP FRCPCH 《Pediatric pulmonology》2010,45(6):566-568
Pseudomonas aeruginosa (PsA) is the most common pathogen to cause chronic lung infection in children with cystic fibrosis (CF), and is associated with an increase in both morbidity and mortality. Whilst the non‐mucoid strain can be eradicated, it is believed that mucoid PsA is difficult, if not impossible, to eradicate. We hypothesized that with modern and aggressive antibiotic regimes, mucoid PsA can be eradicated in children with CF. We investigated this hypothesis through a retrospective review of respiratory tract cultures of children with CF at The Royal Brompton Hospital, London. Children aged under 16 with a confirmed diagnosis of CF and mucoid PsA on respiratory tract culture during a defined 9‐year period were eligible for inclusion. Respiratory tract culture results were followed up for each patient to establish whether children remained infected with mucoid PsA and specifically to identify clearance of infection. Factors which may have been associated with persistence or clearance were also sought. One hundred sixteen children had the minimum dataset, and of these patients 67 (58%) cleared mucoid PsA for more than 1 year. Of the 67 patients who cleared mucoid PsA for more than 1 year, 38 (57%) patients remained clear of mucoid PsA at the last available culture (median 30, range 2–106 clear cultures, and median 55, 12–103 months clear). We conclude that isolation of mucoid PsA does not necessarily equate to lifelong infection. We suggest that trials of eradication of mucoid PsA at first isolation are required. Pediatr Pulmonol. 2010; 45:566–568. © 2010 Wiley‐Liss, Inc. 相似文献