Edgwise矫治器在固定外伤松动牙中的应用

目的 寻求一种固定外伤松动乳牙或年轻恒牙的新方法。方法 43例4～14岁的66颗外伤松动牙，常规粘结托槽、方丝及结扎丝“8”字结扎固定，3个月后拆除。治疗前、治疗后1个月、2个月、3个月、半年拍摄根尖片，观察愈合情况。结果 75．7％正常愈合，15．2％根吸收，3．0％牙冠变色，3．0％牙冠变色。结论 Edgwise托槽应用于外伤松动牙的固定安全、简便、损伤小、易清洁，效果满意。     

Oral lichen planus: a preliminary clinical study on treatment with tazarotene

OBJECTIVE: The rationale for using tazarotene in oral lichen planus (OLP) is its regulatory action on the growth and differentiation of keratinocytes and on inflammation. This randomized, placebo-controlled study addresses evaluation of the effects of topic tazarotene in the treatment of OLP. DESIGN: The degree of lesions before and after treatment scored by a 6-score scale in six cases treated with tazarotene was statistically compared with those of six controls treated with placebo. SUBJECTS: Twelve patients with hyperkeratosic OLP were randomly allocated to treatment with tazarotene gel 0.1% b.i.d. or with placebo for eight consecutive weeks. METHODS: The statistical comparison was executed by means of Wilcoxon analysis for paired data. RESULTS: Patients treated with tazarotene presented a significant reduction of their lesions as compared with the control group. Among transitory side-effects, burning sensation and taste abnormalities were observed. CONCLUSION: Topical tazarotene may be a valuable therapeutic tool in the treatment of hyperkeratotic OLP.     

上颌前磨牙颈部宽、厚、曲度的测量分析

目的：手工测量并获取自然上颌前磨牙颈部数据，为上颌前磨牙区种植美学基台研究设计提供基础数据，并为种植修复临床提供参考。方法：采用高精度游标卡尺测量608个离体上颌前磨牙（其中上颌第一前磨牙296个，上颌第二前磨牙312个）颈部宽度和厚度，牙颈曲度，釉牙骨质界（CEJ）下1．5mm颈宽、颈厚；运用SPSS 13．0软件对所测数据作统计学处理。结果：测量并分析得出各指标的均值、标准差、上下四分位间距值。结论：所测数据是对西安地区人前磨牙颈部数据的进一步补充完善，为西安地区上颌前磨牙区牙颈部修复美学、种植体牙龈美学成型基台的设计研发提供数据支持。     

唇腭裂患者牙槽嵴数字化模型建立及分析的初步探讨

目的 通过三维激光扫描建立唇腭裂患者牙槽嵴的数字化模型，为唇腭裂患者的模型分析建立科学方法。方法 唇裂修复术前于全麻状态下对1例右侧完全性唇腭裂患者的上颌无牙颌制取模型，用激光扫描仪扫描，通过计算机逆向工程软件进行模型重建。结果 此法可在重建模型上设定测量参考点9个，并可测出各标志点间的距离；模型可切割后测量和计算。结论 激光扫描三维分析方法是分析唇腭裂患者牙槽嵴形态及方向改变的一种理想方法，应用此模型可量化分析唇腭裂患者随生长发育而变化的上颌牙槽嵴形态。     

Rosiglitazone reduces the evolution of experimental periodontitis in the rat

The peroxisome proliferator-activated receptor-gamma (PPAR-gamma) receptor appears to play a pivotal role in the regulation of cellular proliferation and inflammation. Recent evidence also suggests that rosiglitazone, a PPAR-gamma agonist, reduces acute and chronic inflammation. We hypothesized that rosiglitazone would attenuate periodontal inflammation. In the present study, we investigated the effects of rosiglitazone in a rat model of ligature-induced periodontitis. At day 8, ligation significantly induced an increase in neutrophil infiltration, as well as of gingivomucosal tissue expression of iNOS, nitrotyrosine formation, and poly (ADP-ribose) polymerase activation. Ligation significantly increased Evans blue extravasation in gingivomucosal tissue and alveolar bone destruction. Intraperitoneal injection of rosiglitazone (10 mg/kg 10% DMSO daily for 8 days) significantly decreased all of the parameters of inflammation, as described above. Analysis of these data demonstrated that rosiglitazone exerted an anti-inflammatory role during experimental periodontitis, and was able to ameliorate the tissue damage associated with ligature-induced periodontitis.     

Computer-aided direct ceramic restorations: a 10-year prospective clinical study of Cerec CAD/CAM inlays and onlays

PURPOSE: The objective of this follow-up study was to examine the performance of Cerec inlays and onlays in terms of clinical quality over a functional period of 10 years. MATERIALS AND METHODS: Of 200 Cerec inlays and onlays placed in a private practice between 1989 and early 1991, 187 restorations were observed over a period of 10 years. The restorations were fabricated chairside using the Cerec-1 computer-aided design/manufacturing (CAD/CAM) method and Vita MK I feldspathic ceramic. An adhesive technique and luting composite resin were used for seating the restorations. After 10 years, the clinical performance of the restorations was evaluated using modified USPHS criteria. The results were used to classify success and failure. RESULTS: According to Kaplan-Meier analysis, the success rate of Cerec inlays and onlays dropped to 90.4% after 10 years. A total of 15 (8%) failures were found in 11 patients. Of these failures, 73% were caused by either ceramic fractures (53%) or tooth fractures (20%). The reasons for the remaining failures were caries (20%) and endodontic problems (7%). The three-surface Cerec reconstructions were found to have the most failures. CONCLUSION: The failure rate of 8% and the drop of the survival probability rate to 90.4% after 10 years of clinical service of Cerec-1 CAD/CAM restorations made of Vita MK I feldspathic ceramic appear to be acceptable in private practice. This is particularly true in light of the very high patient satisfaction.