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81.
Rodrigues Renata Prata Cunha Bernardes de Andrade Vieira Walbert Siqueira Walter Luiz Blumenberg Cauane de Macedo Bernardino talo Cardoso Srgio Vitorino Flores-Mir Carlos Paranhos Luiz Renato 《Clinical oral investigations》2020,24(7):2203-2217
Clinical Oral Investigations - To assess whether salivary urea and creatinine levels accurately reflect their serum levels in blood samples of adults to detect chronic kidney disease. A systematic... 相似文献
82.
Machado Felipe Paiva Khoury Rayana Duarte Toia Cassia Cestari Flores Orozco Esteban Isai de Oliveira Felipe Eduardo de Oliveira Luciane Dias da Rosa Cardoso Flávia Goulart Valera Marcia Carneiro 《Clinical oral investigations》2020,24(9):3169-3179
Clinical Oral Investigations - To compare the microbial load and composition and to determine the lipopolysaccharides (LPS) and lipoteichoic acid (LTA) concentrations found in primary apical... 相似文献
83.
Douglas Mesadri Gewehr Gabriela Rodrigues Salgueiro Lucia de Noronha Fernando Bermudez Kubrusly Luiz Fernando Kubrusly Gabriel Antonio Coltro Paola Cardoso Preto Andressa de Souza Bertoldi Heloisa Iacomo Vieira 《Arquivos brasileiros de cardiologia》2020,115(3):480
Background The monocrotaline (MCT)-induced pulmonary arterial hypertension model is one of the most reproduced today, presenting as a limitation the absence of plexiform lesions, typical manifestations of the severe disease in humans.Objective To evaluate the severity of MCT-induced pulmonary arteriopathy by pathological findings of lung and heart tissue samples, clinical course and 37-day survival.Methods Fifty male Wistar rats were divided into one of the four groups – control (CG) (n = 10) and three intervention (MCT) groups. The MCT groups received intraperitoneal injection (60 mg/kg) of MCT and remained exposed to the substance for 15 days (G15, n = 10), 30 days (G30, n = 10) and 37 days (G37, n = 20). At the end of each period, the animals were sacrificed, and pulmonary and cardiac tissues were collected for anatomopathological and morphometric analysis. The Kruskal-Wallis test was used, considering a level of significance of 5%.Results In the lungs of MCT animals, lesions related to pulmonary arteriopathy were found, including muscularization of the arterioles, hypertrophy of the middle layer and concentric neointimal lesions. Complex lesions were observed in MCT groups, described as plexiform and plexiform-like lesions. Right ventricular hypertrophy was evidenced by increased thickness and diameter of the cardiomyocytes and a significant increase in the right ventricular wall thickness (p <0.0000).Conclusion The MCT model was able to generate moderate-severe pulmonary arteriopathy associated with secondary right ventricular hypertrophy. The 37-day survival rate was 50%. To our knowledge, this study was the first to note the presence of complex vascular lesions, similar to those observed in patients with severe pulmonary arterial hypertension, in an isolated MCT model. (Arq Bras Cardiol. 2020; 115(3):480-490) 相似文献
84.
Paulo Sérgio da Silva Márcio Portugal Trindade Cartacho Casimiro Cardoso de Castro Marcello Fonseca Salgado Filho Ant?nio Carlos Aguiar Brand?o 《Brazilian Journal Of Cardiovascular Surgery》2015,30(4):449-458
Objective
To evaluate the influence of pulmonary hypertension in the ultra-fast-track anesthesia technique in adult cardiac surgery.Methods
A retrospective study. They were included 40 patients divided into two groups: GI (without pulmonary hypertension) and GII (with pulmonary hypertension). Based on data obtained by transthoracic echocardiography. We considered as the absence of pulmonary hypertension: a pulmonary artery systolic pressure (sPAP) <36 mmHg, with tricuspid regurgitation velocity <2.8 m/s and no additional echocardiographic signs of PH, and PH as presence: a sPAP >40 mmHg associated with additional echocardiographic signs of PH. It was established as influence of pulmonary hypertension: the impossibility of extubation in the operating room, the increase in the time interval for extubation and reintubation the first 24 hours postoperatively. Univariate and multivariate analyzes were performed when necessary. Considered significant a P value <0.05.Results
The GI was composed of 21 patients and GII for 19. All patients (100%) were extubated in the operating room in a medium time interval of 17.58±8.06 min with a median of 18 min in GII and 17 min in GI. PH did not increase the time interval for extubation (P=0.397). It required reintubation of 2 patients in GII (5% of the total), without statistically significant as compared to GI (P=0.488).Conclusion
In this study, pulmonary hypertension did not influence on ultra-fast-track anesthesia in adult cardiac surgery. 相似文献85.
86.
Generation of non MHC restricted killing in non-cytotoxic T-lymphocytes from leukaemia patients 总被引:1,自引:0,他引:1
Lina Matera Estela Cardoso Luisella Caudana Michael Moore 《British journal of haematology》1987,65(2):151-157
Experiments were undertaken to determine whether the depression of natural killer (NK) activity previously observed in the peripheral blood lymphocytes (PBL) of leukaemia patients in remission extended to NK-like precursors in the blood. T-lymphocytes (E+) from leukaemia patients and normal subjects were depleted of IgG Fc-receptor-bearing (gamma FcR) fresh NK cells by passage over immune complex-coated monolayers. gamma FcR - E + PBL were cultured alone or with DAUDI cells. On day 5 of culture, cytotoxicity toward the NK-sensitive cell lines K562 and MOLT-4 was evaluated in the responder lymphocytes of leukaemia patients and controls. Negligible NK-like cytotoxicity was found in both FcR - E + PBL responder populations cultured alone. By contrast, stimulation with DAUDI induced high levels of K562 and MOLT-4 cytotoxicity in leukaemia as well as in normal responder cells. Complement-mediated cytotoxicity experiments using various McAb demonstrated that in both normal and leukaemia cultures NK-like effectors react with the pan-T OKT3 McAb and with the OKT11 McAB directed to the SRBC receptor, but not with Leu 1 1b and OKM1 McAbs, directed against antigens expressed on peripheral blood NK cells. Fractionation of the responder cells on discontinuous Percoll gradients showed that most of this activity was present in the highly dividing blast cell fraction. 相似文献
87.
Randomized Clinical Trial of Four Adhesion Strategies in Posterior Restorations—18‐Month Results 下载免费PDF全文
Flávia B. Delbons DDS MS PhD Jorge Perdigão DMD MS PhD Edson Araujo DDS MS PhD Charles A. Melo Freire DDS Danilo D. Caldas DDS MS PhD Jorge L. Cardoso DDS Margarida Pagani DDS Gilberto A. Borges DDS MS PhD Rodrigo B. Lima DDS 《Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]》2015,27(2):107-117
88.
Early withdrawal of calcineurin inhibitor from a sirolimus‐based immunosuppression stabilizes fibrosis and the transforming growth factor‐β signalling pathway in kidney transplant 下载免费PDF全文
89.